Thu.May 23, 2024

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New data show the HPV vaccine prevents cancer in men, too. Why don’t more people get it?

STAT

You’d think if there were a vaccine that would prevent tens of thousands of cases of cancer a year, people would want it for themselves and for their kids. But new data being released Thursday ahead of the annual meeting of the American Society of Clinical Oncology show that just isn’t the case.

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Researchers combine herpes virus with cancer vaccine to treat brain cancer in children

Pharma Times

High-grade gliomas are rare, malignant tumours which account for up to 12% of all childhood brain tumours

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Trending Sources

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Opinion: Addressing health care workers’ trauma can help fight burnout

STAT

Burnout is a growing crisis in health care: More than 50% of health care professionals report symptoms of it. Addressing the trauma they face at work can help. Halting burnout straddles the tension between addressing the individual factors versus the organizational factors behind it. It was once believed that burnout was related to health workers’ inability to cope with the natural stresses of their job.

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UK MRC and AstraZeneca partner for translational clinical research

Pharma Times

The partnership will provide six MRC clinical fellows with industry placement opportunities

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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STAT+: FDA advisers endorse Guardant Health’s colon cancer screening test

STAT

An independent panel of advisers to the Food and Drug Administration recommended the agency approve Guardant Health’s blood-based colon cancer detection test. If the agency follows the recommendation, it will clear an early hurdle for the test’s broader adoption. The expert panel spent hours listening to presentations from Guardant, the FDA, and members of the public before voting on the screening test, called Shield.

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Opinion: Making the case for fair compensation in clinical trials

STAT

I’ve been on three sides of the health care equation: I’ve beaten stage 4 colorectal cancer, I’m the mother of a son with an ultra-rare genetic abnormality, and I now work as the chief patient officer for Parexel, one of the world’s largest clinical research organizations. Having seen what people go through as they navigate the health care system and try to participate in clinical trials, I know that the road to participation must be smoother and easier — and n

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ASCO24: An early look at cancer drug study results

BioPharma Dive

Clinical trial abstracts posted by ASCO Thursday give a peek at anticipated datasets from Immunocore, Merck & Co., J&J and Arcus Biosciences.

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Reversing progress, stroke rates are rising, especially in working-age adults

STAT

Stroke prevalence has been climbing over the past decade, reversing a steady decline among all Americans while rising the most among adults under 65, a new CDC analysis reports. Strokes still strike more adults older than 65, but the increase at younger ages mirrors another recent turnaround: rates of heart failure deaths, which had been dipping, are rising the most in adults under 45.

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NHSE urged to provide full list of available DPPs

The Pharmacist

NHS England must provide a full list of organisations with available designated prescribing practitioners (DPPs) before placement information is released to students, the Company Chemists’ Association (CCA) has urged. The association warned that without such a list outlining where to source DPPs, community pharmacy businesses could be ‘forced to offer fewer foundation placements than they […] The post NHSE urged to provide full list of available DPPs appeared first on The Pharmacist.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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In light of H5N1 outbreak, U.S. in talks with mRNA vaccine makers on bird flu

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. Wall Street had a big reaction to H5N1 bird flu news yesterday. Was it warranted? We’ll discuss that today.

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Orna, a circular RNA specialist, acquires a buzzy startup

BioPharma Dive

After laying off staff late last year, Orna is expanding through the purchase of ReNAgade Therapeutics, which was built around technology designed to more effectively deliver RNA-based medicines.

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STAT+: Cytokinetics CEO Robert Blum is on my Worst CEO shortlist again, and other thoughts

STAT

Thoughts about Cytokinetics after Wednesday night’s financing announcement : 1. Management is raising $500 million at $51 per share, when the stock was at $45 per share before the aficamtem study readout in December. That’s shocking. Somehow, management has not only removed all the M&A premium from the stock, but much or most of aficamtem’s value, too. 2.

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Merck builds in cell, gene therapies with Mirus Bio deal

pharmaphorum

Merck KGaA has agreed to a $600m deal to buy Mirus Bio, a specialist in transfection reagents used in the production of cell and gene therapies.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: Ahead of ASCO, J&J reports mixed data on next-generation radiopharmaceutical

STAT

An early-stage clinical trial of a radiopharmaceutical drug developed by Johnson & Johnson showed some signs of efficacy in prostate cancer patients, newly released data show, but four participants in the trial died. The drug, JNJ-6420, is designed to treat metastatic castration-resistant prostate cancer by delivering radioactive isotopes directly to cancer cells.

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AstraZeneca and Nona Biosciences sign agreement for monoclonal antibody

Pharmaceutical Technology

AstraZeneca has entered into a worldwide licence and option agreement with Nona Biosciences for a preclinical monoclonal antibody.

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STAT+: Biotechs turn to gene silencing for obesity drugs that can last longer than Wegovy

STAT

Enticed by the immense market opened by GLP-1 weight loss drugs Wegovy and Zepbound, a handful of biotech companies are trying to develop next-generation, longer-lasting therapies based on a very different approach: RNA interference. This Nobel Prize-winning science works by degrading the biological blueprints that RNA use to make proteins — without the genetic instructions, the troublesome proteins are never made and the gene is essentially muted.

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Certain menopausal hormone therapy could raise ovarian cancer risk, study finds

BioPharma Dive

The findings, from two trials involving tens of thousands of women, could influence guidelines around the use of hormonal treatment for menopausal symptoms.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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STAT+: Pharmalittle: We’re watching a Cytokinetics deal with Royalty Pharma, Cue Health shutting down, and more

STAT

Top of the morning to you. I’m filling in for Ed Silverman this morning, which means you’re getting Brooklyn instead of the Pharmalot compound, Barry’s tea instead of flavored coffee, and most shockingly, adorable cats. I know. But I can still line up some listening material for the morning news. I know, we are all eagerly awaiting the return of our beloved Pharmalot, but let’s get to it.

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Second fire at Novo Nordisk in a week now under control

pharmaphorum

Novo Nordisk’s second facility fire in a week is under control, although the office in Bagsvaerd affected by the latest blaze isn’t expected to be salvageable.

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STAT+: Setting the table: What to expect at this year’s ASCO meeting

STAT

This is the online edition of Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up here  to get it delivered every Thursday to their inbox. I have one more, admittedly braggy thing to say about last week’s STAT Breakthrough Summit West in San Francisco. Of course we curated an incredible roster of influential industry leaders to speak on stage.

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Chinese firm throws lifeline to Pfizer UK plant workers

pharmaphorum

China’s Asymchem Laboratories has agreed to take over the operation of a Pfizer manufacturing facility in Sandwich, UK, saving dozens of jobs.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Listen: More tumult at BIO & coercive care for sickle cell patients

STAT

How does a drug industry lobbying group move forward after years of upheaval, including having four CEOs in four years? This week on “The Readout LOUD,” STAT’s Chief Washington Correspondent Rachel Cohrs Zhang joins us to discuss the layoffs at trade group BIO and how things may be changing at the trade group. We also invite STAT reporter Eric Boodman on to talk about his new investigative series of stories exploring how Black women with sickle cell disease were coerced into

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Cytokinetics eyes go-it-alone strategy for aficamten

pharmaphorum

Cytokinetics has been a top biotech takeover candidate for some time, thanks to blockbuster speculation about its lead drug aficamten, but a $1 billion-plus set of financing deals shows it is prepared to go to market on its own.

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Pharma companies urged to act on antimicrobials to combat drug resistance

Express Pharma

A new report from the Access to Medicine Foundation calls for urgent changes in research and development (R&D) to ensure new antibiotics and antifungals reach patients facing drug-resistant infections. The report examines five late-stage antimicrobial projects targeting severe drug-resistant pathogens, revealing that structured advance planning for access and stewardship is not yet standard among companies.

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Progressing personalised cell therapies in oncology

European Pharmaceutical Review

Last month, CARVYKTI ® (ciltacabtagene autoleucel; cilta-cel) was the first BCMA-targeted CAR-T cell therapy to be approved for second-line treatment of multiple myeloma by the US Food and Drug Administration (FDA). In this Q&A, Dr Imran Khan, PhD, Vice President Medical Affairs, Hematology at Johnson & Johnson Innovative Medicine, highlights the current landscape of CAR T therapies such as CARVYKTI and touches on the future direction of the sector.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.