Mon.Sep 09, 2024

article thumbnail

Medicine struggles to define chronic Lyme. Long Covid has only made it harder

STAT

Going to the doctor is already tricky enough for people with chronic symptoms of Lyme disease. Their concerns often dismissed by mainstream medicine, those patients now face an additional hurdle: ruling out long Covid.  The two illnesses — one seeping in over the course of decades and another suddenly springing to life on a massive scale — share many qualities, including being widely misunderstood.

363
363
article thumbnail

Lilly lays down $1B to be ‘first in biology’ with obesity gene therapies

PharmaVoice

The deal, which targets metabolic diseases, is one of a few by Big Pharma to develop lncRNA therapies.

261
261
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Biden administration finalizes rules to ensure insurers pay for mental health care 

STAT

The Biden administration on Monday announced it would finalize a highly anticipated proposal meant to force health insurers to cover mental health care on the same basis as physical health conditions.  It is the latest salvo in a long-running federal government effort to crack down on insurance plans skimping on treatment for conditions including anxiety, depression, and addiction.

362
362
article thumbnail

SAEM Clinical Images Series: An Unusual Foreign Body

ALiEM - Pharm Pearls

A 61-year-old female with a past medical history of hypertension, hyperlipidemia, type 2 diabetes, and normal pressure hydrocephalus s/p VP shunt (last revision nine months ago) presented to the Emergency Department (ED) for evaluation after noticing a “string” coming out of her anus today. Associated symptoms included nausea and a mild headache for one day, and one episode of vomiting prior to arrival.

Diabetes 152
article thumbnail

Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

article thumbnail

STAT+: With a win in lung cancer, biotech’s wealthiest outsider surfs to new heights

STAT

On Sunday, a small biotech company called Summit Therapeutics won a remarkable victory, saying its experimental drug outperformed Merck’s Keytruda , the world’s best-selling drug, in non-small cell lung cancer, the disease that represents Keytruda’s biggest market. By itself, Summit’s victory would be a dramatic story, although not an unheard of one in the unpredictable world of biotechnology.

More Trending

article thumbnail

Opinion: How Pfizer ended up passing on my GLP-1 work back in the early ’90s

STAT

One of the biopharma industry’s marvels of the 2020s has been the enormous medical and financial success of the GLP-1 class of drugs. But the path to commercialization of these therapies was far more complex than most understand, and some of the earliest history has never been presented. Beginning in 1988, I was part of what I believe was the earliest commercial effort to develop GLP-1 as a metabolic therapy.

article thumbnail

Community pharmacy could consider 'working to rule', say CPE and NPA

The Pharmacist

Community pharmacy could consider 'working to rule' under GP-style collective action, sector leaders have suggested. Speaking at the Avicenna Heathrow conference yesterday (8 September 2024), both Community Pharmacy England (CPE) and National Pharmacy Association (NPA) leaders said that 'working to rule' and legal action against the government remained a possibility for the sector.

article thumbnail

STAT+: House passes bill that targets China biotechs

STAT

WASHINGTON — The House Monday passed a bill by 306 to 81 votes to make drug companies stop doing business with some Chinese biotechs within eight years if they want to remain in good standing with the federal government. The BIOSECURE Act would prohibit the U.S. government from contracting with, or providing grants to, companies that do business with a “biotechnology company of concern.

Packaging 347
article thumbnail

WCLC: Summit trumpets data with Keytruda challenger

pharmaphorum

Summit Therapeutics and Akeso's ivonescimab tops Merck's Keytruda in head-to-head phase 3 trial in first-line NSCLC, reported at WCLC.

115
115
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

A race-free algorithm is merely the start for a safety net hospital confronting an onslaught of kidney disease

STAT

NEW YORK — One Brooklyn Health, a safety net hospital system that serves some of this city’s poorest and sickest patients, would seem to be exactly the place to benefit most from the effort to remove race from calculations that assess kidney disease. The patients — mostly Black and insured by Medicaid or Medicare — are a case study in the disparities that run through American kidney care: A large number have advanced disease and require dialysis, but just a handful ge

Hospitals 327
article thumbnail

Huntington’s disease R&D is regaining ground after several disappointments

PharmaVoice

Setbacks haven’t stopped advances by biotechs and pharmas working on new drugs for the inherited brain disorder.

113
113
article thumbnail

How Paralympic athletes are helping science learn more about neuropathic pain

STAT

Elite athletes train and compete under a watchful eye. Fans and coaches track and measure every step, roll, or throw. But for athletes with a spinal cord injury, a key facet of their experience is unknown: neuropathic pain. Unlike musculoskeletal pain — say, from breaking your leg — neuropathic pain resides in the nervous system. And treating it is tricky: you can’t just pop an Advil or Tylenol and wait for the pain to subside.

315
315
article thumbnail

Original pack dispensing allowed from January

The Pharmacist

Pharmacists in England will be allowed to dispense 10% more or less than the prescribed amount in order to dispense medications in the original packs from January 2025. This follows changes to the Human Medicines Regulations (HMRs) that have allowed original pack dispensing (OPD) for private prescriptions since October 2023. Community Pharmacy England (CPE) has […] The post Original pack dispensing allowed from January appeared first on The Pharmacist.

article thumbnail

Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

article thumbnail

Apple pushes into sleep apnea detection but health care integration remains unclear

STAT

CUPERTINO, Calif. — Apple on Monday announced a new Apple Watch feature that will warn users they may have sleep apnea. It’s the latest advance in the company’s decade-long effort to sell its wearable as a tool that can help people live healthier lives. Additionally, the company announced more hearing health features for its wireless earbuds.

311
311
article thumbnail

Government promises 'shift' towards community and prevention

The Pharmacist

The government has committed to three ‘strategic shifts’ for the NHS which includes moving care from ‘hospital to community’ and from ‘treatment to prevention'. The Labour Government also said it wants to shift the NHS from ‘analogue to digital’, in a statement last week (6 September 2024). The comments come as Lord Darzi's investigation into the […] The post Government promises 'shift' towards community and prevention appeared first on The Pharmacist.

Hospitals 111
article thumbnail

STAT+: Merck executive plays down impact of new lung cancer drug data on Keytruda

STAT

With strong data released over the weekend, an experimental Chinese drug showed it could one day become an important therapy for lung cancer patients. But that doesn’t necessarily threaten the market dominance of Keytruda, a top Merck executive said — and some analysts agree. “I see these results as important, but preliminary,” Merck Chief Medical Officer Eliav Barr told STAT, reacting to the presentation Sunday of a Phase 3 clinical trial involving ivonescimab, a dru

302
302
article thumbnail

Digital Solution Implementation

Pharmaceutical Commerce

In the second part of her interview with Pharma Commerce Editor Nicholas Saraceno, Meghan Mullooly, Archbow Consulting’s Vice President, offers advice to pharma manufacturers for successfully applying digital solutions to their patient support programs.

111
111
article thumbnail

Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

article thumbnail

With TV drug ads, what you see is not necessarily what you get

STAT

Triumphant music plays as cancer patients go camping, do some gardening, and watch fireworks in  ads for Opdivo+Yervoy , a combination of immunotherapies to treat metastatic melanoma and lung cancer.  Ads for Skyrizi , a medicine to treat plaque psoriasis and other illnesses, show patients snorkeling and riding bikes — flashing their rash-free elbows.

Diabetes 287
article thumbnail

How Chiesi is walking the walk on pharma sustainability

pharmaphorum

Discover how Chiesi is leading the way in pharmaceutical sustainability by partnering with EcoVadis and implementing innovative practices. Learn how they are making a positive impact on the environment and society.

111
111
article thumbnail

Opinion: Breakthrough therapies have given Duchenne muscular dystrophy families like mine hope — and new fears

STAT

Duchenne muscular dystrophy has seen more progress in the past 15 months (give or take) than in the last couple of decades combined. In that time, the Food and Drug Administration has approved three new therapies: Elevidys (delandistrogene moxeparvovec-rokl), the first micro-dystrophin gene therapy; Duvyzat (givinostat), a non-steroidal HDAC inhibitor; and Agamree (vamorolone), a new corticosteroid.

286
286
article thumbnail

Driving economic growth in UK with commercial clinical trials

European Pharmaceutical Review

A report from Frontier Economics has highlighted the major benefit industry clinical trials have had on UK’s economy. For instance, it has supported its growth and the job market, the research showed. Of the 65,000 jobs generated, 21,000 individuals were employed directly by the pharmaceutical industry to deliver trials, according to the data. While industry clinical trials in the UK have reduced , the Association of the British Pharmaceutical Industry (ABPI) stated that if the activity assumes

105
105
article thumbnail

Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

article thumbnail

STAT+: RayzeBio, Dice alums raise $370 million for new autoimmune startup

STAT

After leading his previous company through a back-to-back IPO and M&A deal, the former chief executive of RayzeBio has raised $370 million to develop autoimmune therapies he believes could be “mega-blockbusters.” Those drugs are being developed by San Diego startup Candid Therapeutics, which launched Monday with financing from more than 20 investors.

286
286
article thumbnail

Romaco India opens solids processing experience centre in Hyderabad

Express Pharma

Romaco India inaugurated its Solids Processing Experience Center on the evening of September 4, 2024, in Sultanpur, Hyderabad. Located in the Medical Device Park at the 4th Exit of Outer Ring Road, the facility is designed to provide hands-on experience with advanced solids processing technologies. The centre features a development laboratory and equipment showroom, offering support for key processes like granulation, fluid-bed granulation, drying, pellet coating, hot melt coating, tableting, an

Dosage 105
article thumbnail

STAT+: Relay discloses encouraging results for experimental breast cancer treatment

STAT

Relay Therapeutics disclosed encouraging results for its key breast cancer drug and plans to advance the experimental treatment, called RLY-2608, to a late-stage clinical trial, the biotech firm said on Monday. The new data come from an open label phase 1/2 trial on RLY-2608 combined with fulvestrant, an endocrine therapy for breast cancer, showing a third of patients with measurable disease responded to the treatment.

Labelling 280
article thumbnail

FOPE and PharmaState Academy continue to drive pharma quality with PULSE initiative

Express Pharma

On September 8, 2024, the Federation of Pharma Entrepreneurs (FOPE) and PharmaState Academy hosted Session 4 of the PULSE (Pharma Upgradation & Learning Series for Excellence) initiative. The session, which focused on Qualification and Validation, saw participation from over 200 attendees. It underscored the industry’s demand for learning about the Revised Schedule M and its impact on pharmaceutical manufacturing.

article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.