STAT

OCTOBER 7, 2024

LONDON — A pair of scientists who discovered a type of RNA molecule that helps control the activity of genes — allowing our cells to perform all their myriad of functions in different tissues throughout the body — won the 2024 Nobel Prize in medicine or physiology on Monday. The award went to Victor Ambros and Gary Ruvkun for their research into microRNA, which the Nobel committee described as a “groundbreaking discovery [that] revealed a completely new principle of g

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PharmaVoice

OCTOBER 7, 2024

Through real-world data, an AI company found that popular weight loss drugs could be a preventive measure for patients at risk of heart attack and stroke.

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STAT

OCTOBER 7, 2024

From the earliest days of the H5N1 bird flu outbreak in dairy cattle, experts watching the evolving situation have worried about California.  The Golden State has the country’s largest concentration of dairy farms, roughly 1,100 herds. The concern has been if the virus got into California, the prospects for spread would be huge and containment a challenge.

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ALiEM - Pharm Pearls

OCTOBER 7, 2024

A 52-year-old female with a past medical history of hypertension and prediabetes presented to the emergency department with double vision that started one day prior to arrival. She stated that her double vision improved when she closed one eye. She denied trauma, headache, neck pain, dizziness, dysphagia, numbness, tingling, weakness, or gait instability.

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STAT

OCTOBER 7, 2024

Over the past 150 years, humanity has unleashed unimaginable energy by splitting atoms and developed machines that allow us to soar through the skies. But arguably, our species’ most profound change has been far more basic: People generally live a lot longer than they used to. This trend has now substantially slowed in wealthier nations, which appear to be nearing a limit in life expectancy improvements from modern medicine, according to a new study.

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BioPharma Dive

OCTOBER 7, 2024

The Cambridge, Massachusetts-based biotech is using what it calls ligand-siRNA conjugates to reach drug targets in the kidney, which historically have been difficult to reach with RNA therapies.

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pharmaphorum

OCTOBER 7, 2024

UK Health Secretary Wes Streeting has announced plans to allow NHS England to share primary care data with scientific researchers, taking on some of the responsibility held by GPs. The minister told the Royal College of General Practitioners (RCGP) annual conference that, while many UK patients have given their consent for their data to be shared with studies run by the likes of the UK Biobank, Genomics England, and Our Future Health, they "still see, far too often, that this data is not shared

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STAT

OCTOBER 7, 2024

An organization scouring thousands of existing drugs to see if any can cure hard-to-treat diseases has a powerful new ally: Janet Woodcock, who for decades was one of the most influential figures at the Food and Drug Administration. The group, Every Cure, is led by physician David Fajgenbaum, who has told his own story again and again: When he was a young medical student, he came down with a rare disease that turned his athletic, football-honed body bloated and weak and nearly killed him not onc

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European Pharmaceutical Review

OCTOBER 7, 2024

New results from a first-of-its-kind study reports that a CAR-T cell therapy provided similar efficacy and safety to relapsed or refractory multiple myeloma patients administered with the treatment in clinical trials. For example, of the 236 patients who received infusions of ciltacabtagene autoleucel (cilta-cel), data shows that 89 percent responded to the treatment.

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STAT

OCTOBER 7, 2024

Gary Ruvkun is used to getting awards — but for him, the Nobel Prize is in a class of its own. “I’ve won 10 to 20 awards in the last 20 years, but never had a press conference with cameras and nothing like this,” Ruvkun, who along with Victor Ambros received the 2024 award in medicine or physiology on Monday, said at a press conference at Massachusetts General Hospital.

Medical Schools 338

Medical Schools Diabetes Hospitals 338

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

Express Pharma

OCTOBER 7, 2024

Alembic Pharmaceuticals (Alembic) has announced its early participation in the Prime Minister’s Internship Scheme. This initiative aims to provide internship opportunities to one crore young Indians in the country’s top 500 companies over the next five years. Alembic is among the first companies in India to partake in this scheme, having already listed 125 internship positions across key technical areas within the company.

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STAT

OCTOBER 7, 2024

From antibody-drug conjugates to immuno-oncology checkpoint inhibitors, China is the world’s most closely watched rising biotechnology power. The growth of China’s industry can be attributed to a number of factors, including beneficial state policies and fresh injections of funding. There has also been bold regulatory reform. Since 2015, the country’s National Medical Products Administration has issued one milestone regulation after another, greatly accelerating the process

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Vaccines 332

pharmaphorum

OCTOBER 7, 2024

Learn how Oliver Stohlmann nurtures the mentor in you, emphasising values like integrity. Discover how you can become a mentor and make a difference in someone's life.

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STAT

OCTOBER 7, 2024

The biotech company Scholar Rock reported Monday that its experimental medicine improved motor function in patients with a muscle-wasting disease called spinal muscular atrophy, paving the way for the likely approval of the drug. In a year-long Phase 3 trial, the company tested the drug, called apitegromab, on top of existing treatments for the disease.

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Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

Express Pharma

OCTOBER 7, 2024

In September 2024, the pharmaceutical industry reported 112 deals with a total value of $4.2 billion. This represents a 45.4 per cent decline compared to the same period in 2023. Despite the drop in deal value, the number of deals surpassed the last 12-month average, which stood at 92 deals, although the average deal value during the same timeframe, from September 2023 to August 2024, was much higher at $17.7 billion.

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STAT

OCTOBER 7, 2024

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning. Today, we talk about the legacy that scientist and advocate Sammy Basso leaves behind after dying of complications from progeria at age 28. Also, we highlight a dozen people in the Chinese biopharma sector worth following, and more.

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Drug Pricing Drug Development 260

Pharmaceutical Technology

OCTOBER 7, 2024

The CD7 CAR)-T cell therapy has demonstrated potential in treating patients with relapsed or refractory T-cell leukaemia.

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STAT

OCTOBER 7, 2024

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Why do bad menstrual cramps happen to good people? A study answering that question would get the Gaffney Prize (from me). Until that happens, we’ve got the Nobels. STAT’s Drew Joseph has more below on the first announcement of the week, in physiology or medicine.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

Drug Channels

OCTOBER 7, 2024

Informa Connect’s PBM Contracting Summit December 10-11, 2024 | Chicago, IL Drug Channels readers save 10% with code 24DRCH10 * Experts from across the US come together each year at the PBM Contracting Summit to gain innovative and practical contracting strategies, master PBM innovation and design, improve patient care management and rising costs, understand the current legislative issues impacting contract negotiations and more.

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Drug Pricing Biosimilars 97

The Pharmacist

OCTOBER 7, 2024

Around 8% of community pharmacists in England were qualified as independent prescribers (IPs) in 2023, an NHS England workforce survey has suggested. In 2023, around 2,217 community pharmacists were IP qualified, or around 8% of the total community pharmacist workforce - an estimated 27,485, according to the latest data from the Community Pharmacy Workforce survey. […] The post Fewer than one in ten community pharmacists can prescribe, NHSE suggests appeared first on The Pharmacist.

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Community Pharmacies 96

pharmaphorum

OCTOBER 7, 2024

The recent Mpox outbreak highlights the urgent need for new approaches to therapeutic antibody research. Discover how the World Health Organization (WHO) and CDC are responding to this public health crisis.

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Pharmaceutical Technology

OCTOBER 7, 2024

The safety review was requested by the French medicines agency, citing new safety reports that alter the risk profile of finasteride.

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Pharmacy Management

pharmaphorum

OCTOBER 7, 2024

Stay updated on the latest advancements in early detection and innovative therapies targeting tau pathology in Alzheimer’s disease. Learn more about the cutting-edge research and treatments available.

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Drug Patent Watch

OCTOBER 7, 2024

Pharmacokinetics (PK) plays a crucial role in the development and approval of generic drugs. PK studies help ensure that generic drugs are bioequivalent to their brand-name counterparts, meaning they have similar absorption, distribution, metabolism, and excretion (ADME) profiles.

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pharmaphorum

OCTOBER 7, 2024

Victor Ambros and Gary Ruvkun have shared this year's Nobel Prize in Physiology or Medicine for their discovery of microRNA

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BioPharma Dive

OCTOBER 7, 2024

The study, of Intellia’s treatment for hereditary angioedema, is the second Phase 3 trial the biotech has begun testing its “in vivo” gene editing medicines.

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pharmaphorum

OCTOBER 7, 2024

AstraZeneca pays $100m upfront for rights to an oral lipoprotein(a) drug developed by Chinese biotech CSPC Pharmaceutical.

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Drug Development 103

Pharma Times

OCTOBER 7, 2024

Biotech company moves forward with phase 2 trial for precision cancer surgery

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pharmaphorum

OCTOBER 7, 2024

A trial of AstraZeneca and Avillion's first-in-class asthma rescue inhaler Airsupra has been halted early after the drug outperformed a standard therapy.The phase 3b BATURA study showed Airsupra (albuterol/budesonide) achieved a statistically significant reduction in the risk of severe asthma exacerbations when used as needed for rescue therapy compared to albuterol on its own.

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World Pharma News

OCTOBER 7, 2024

Imagine a world where your own immune cells are transformed into cancer-fighting superheroes. This is the promise of CAR-T cell therapy, a groundbreaking treatment that’s already saving lives. In this therapy, patients' own immune cells are collected, genetically engineered so that they specifically target cancer cells, then returned to the body. The result is a potent new option for battling blood cancers.

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Immunity Immunization 79

pharmaphorum

OCTOBER 7, 2024

Learn how accessible technology support can help in managing the UK's ADHD medication supply crisis within the NHS, and improve outcomes for patients.

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BioPharma Dive

OCTOBER 7, 2024

Phase 3 findings could position the biotech’s therapy to become part of a “new standard” for SMA, its CEO said, while boosting research into whether it can preserve muscle in people with obesity.

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