Mon.Oct 07, 2024

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2024 Nobel prize in medicine: Ruvkun, Ambros win for discovery of microRNA

STAT

LONDON — A pair of scientists who discovered a type of RNA molecule that helps control the activity of genes — allowing our cells to perform all their myriad of functions in different tissues throughout the body — won the 2024 Nobel Prize in medicine or physiology on Monday. The award went to Victor Ambros and Gary Ruvkun for their research into microRNA, which the Nobel committee described as a “groundbreaking discovery [that] revealed a completely new principle of g

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Novo’s GLP-1 Wegovy could improve heart health for millions more than previously thought, AI study finds

PharmaVoice

Through real-world data, an AI company found that popular weight loss drugs could be a preventive measure for patients at risk of heart attack and stroke.

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Wealthy nations might be reaching a life expectancy limit, study suggests — at least for now

STAT

Over the past 150 years, humanity has unleashed unimaginable energy by splitting atoms and developed machines that allow us to soar through the skies. But arguably, our species’ most profound change has been far more basic: People generally live a lot longer than they used to. This trend has now substantially slowed in wealthier nations, which appear to be nearing a limit in life expectancy improvements from modern medicine, according to a new study.

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SAEM Clinical Images Series: Doubly Double Vision

ALiEM - Pharm Pearls

A 52-year-old female with a past medical history of hypertension and prediabetes presented to the emergency department with double vision that started one day prior to arrival. She stated that her double vision improved when she closed one eye. She denied trauma, headache, neck pain, dizziness, dysphagia, numbness, tingling, weakness, or gait instability.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: A global revolution in funding mental health care is coming

STAT

The conversation about the mental health crisis is loud, but at a standstill. Stuck on repeat around the challenges of accessing existing treatments, the situation can appear increasingly hopeless.  I see another future — one far more positive and exciting. We are on the cusp of a revolution in mental health science. In five years’ time, the mental health treatment landscape will look radically different.

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Judo Bio debuts with $100M and a plan to take RNA drugs to the kidney

BioPharma Dive

The Cambridge, Massachusetts-based biotech is using what it calls ligand-siRNA conjugates to reach drug targets in the kidney, which historically have been difficult to reach with RNA therapies.

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More Trending

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Fewer than one in ten community pharmacists can prescribe, NHSE suggests

The Pharmacist

Around 8% of community pharmacists in England were qualified as independent prescribers (IPs) in 2023, an NHS England workforce survey has suggested. In 2023, around 2,217 community pharmacists were IP qualified, or around 8% of the total community pharmacist workforce - an estimated 27,485, according to the latest data from the Community Pharmacy Workforce survey. […] The post Fewer than one in ten community pharmacists can prescribe, NHSE suggests appeared first on The Pharmacist.

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Q&A: How California, now an epicenter for bird flu in dairy cattle, is monitoring the virus

STAT

From the earliest days of the H5N1 bird flu outbreak in dairy cattle, experts watching the evolving situation have worried about California.  The Golden State has the country’s largest concentration of dairy farms, roughly 1,100 herds. The concern has been if the virus got into California, the prospects for spread would be huge and containment a challenge.

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First real-world study reveals encouraging efficacy for cell therapy

European Pharmaceutical Review

New results from a first-of-its-kind study reports that a CAR-T cell therapy provided similar efficacy and safety to relapsed or refractory multiple myeloma patients administered with the treatment in clinical trials. For example, of the 236 patients who received infusions of ciltacabtagene autoleucel (cilta-cel), data shows that 89 percent responded to the treatment.

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2024 Nobel Prize winner Gary Ruvkun on sharing credit and the future of microRNA

STAT

Gary Ruvkun is used to getting awards — but for him, the Nobel Prize is in a class of its own. “I’ve won 10 to 20 awards in the last 20 years, but never had a press conference with cameras and nothing like this,” Ruvkun, who along with Victor Ambros received the 2024 award in medicine or physiology on Monday, said at a press conference at Massachusetts General Hospital.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Mpox shows need for new approaches to therapeutic antibody research

pharmaphorum

The recent Mpox outbreak highlights the urgent need for new approaches to therapeutic antibody research. Discover how the World Health Organization (WHO) and CDC are responding to this public health crisis.

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STAT+: 12 people changing the course of the Chinese biopharma industry

STAT

From antibody-drug conjugates to immuno-oncology checkpoint inhibitors, China is the world’s most closely watched rising biotechnology power. The growth of China’s industry can be attributed to a number of factors, including beneficial state policies and fresh injections of funding. There has also been bold regulatory reform. Since 2015, the country’s National Medical Products Administration has issued one milestone regulation after another, greatly accelerating the process

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NUHS’s CD7 CAR-T cell therapy shows promise for leukaemia

Pharmaceutical Technology

The CD7 CAR)-T cell therapy has demonstrated potential in treating patients with relapsed or refractory T-cell leukaemia.

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STAT+: Scholar Rock drug for spinal muscular atrophy succeeds in late-stage study

STAT

The biotech company Scholar Rock reported Monday that its experimental medicine improved motor function in patients with a muscle-wasting disease called spinal muscular atrophy, paving the way for the likely approval of the drug. In a year-long Phase 3 trial, the company tested the drug, called apitegromab, on top of existing treatments for the disease.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Managing the UK's ADHD medication supply crisis with accessible technology support

pharmaphorum

Learn how accessible technology support can help in managing the UK's ADHD medication supply crisis within the NHS, and improve outcomes for patients.

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The biotech news stories you need to read this morning

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning. Today, we talk about the legacy that scientist and advocate Sammy Basso leaves behind after dying of complications from progeria at age 28. Also, we highlight a dozen people in the Chinese biopharma sector worth following, and more.

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The Role of Pharmacokinetics in Generic Drugs

Drug Patent Watch

Pharmacokinetics (PK) plays a crucial role in the development and approval of generic drugs. PK studies help ensure that generic drugs are bioequivalent to their brand-name counterparts, meaning they have similar absorption, distribution, metabolism, and excretion (ADME) profiles.

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The 2024 Medicine Nobel, and remembering Sammy Basso

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Why do bad menstrual cramps happen to good people? A study answering that question would get the Gaffney Prize (from me). Until that happens, we’ve got the Nobels. STAT’s Drew Joseph has more below on the first announcement of the week, in physiology or medicine.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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NHS England to be given a bigger role in GP data sharing

pharmaphorum

UK Health Secretary Wes Streeting has announced plans to allow NHS England to share primary care data with scientific researchers, taking on some of the responsibility held by GPs. The minister told the Royal College of General Practitioners (RCGP) annual conference that, while many UK patients have given their consent for their data to be shared with studies run by the likes of the UK Biobank, Genomics England, and Our Future Health, they "still see, far too often, that this data is not shared

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Alembic Pharmaceuticals announces early participation in the PM’s internship scheme

Express Pharma

Alembic Pharmaceuticals (Alembic) has announced its early participation in the Prime Minister’s Internship Scheme. This initiative aims to provide internship opportunities to one crore young Indians in the country’s top 500 companies over the next five years. Alembic is among the first companies in India to partake in this scheme, having already listed 125 internship positions across key technical areas within the company.

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EMA starts review into hair loss drugs about potential link to suicidal thoughts 

Pharmaceutical Technology

The safety review was requested by the French medicines agency, citing new safety reports that alter the risk profile of finasteride.

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FOPE and PharmaState Academy address HVAC Systems in pharma manufacturing

Express Pharma

On October 6, 2024, the Federation of Pharma Entrepreneurs (FOPE) and PharmaState Academy conducted Session 6 of the PULSE (Pharma Upgradation & Learning Series for Excellence) initiative, focusing on HVAC Systems and Qualification in pharmaceutical manufacturing. The event attracted over 200 attendees and continued the PULSE series’ role in providing a platform for industry learning.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FluoGuide submits clinical trial application for head and neck cancer treatment

Pharma Times

Biotech company moves forward with phase 2 trial for precision cancer surgery

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MicroRNA pioneers win Nobel Prize for medicine

pharmaphorum

Victor Ambros and Gary Ruvkun have shared this year's Nobel Prize in Physiology or Medicine for their discovery of microRNA

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Informa Connect’s PBM Contracting Summit

Drug Channels

Informa Connect’s PBM Contracting Summit December 10-11, 2024 | Chicago, IL Drug Channels readers save 10% with code 24DRCH10 * Experts from across the US come together each year at the PBM Contracting Summit to gain innovative and practical contracting strategies, master PBM innovation and design, improve patient care management and rising costs, understand the current legislative issues impacting contract negotiations and more.

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Advancements in early detection and innovative therapies targeting tau pathology

pharmaphorum

Stay updated on the latest advancements in early detection and innovative therapies targeting tau pathology in Alzheimer’s disease. Learn more about the cutting-edge research and treatments available.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharma industry deal value falls 45.4% in september 2024 compared to previous year

Express Pharma

In September 2024, the pharmaceutical industry reported 112 deals with a total value of $4.2 billion. This represents a 45.4 per cent decline compared to the same period in 2023. Despite the drop in deal value, the number of deals surpassed the last 12-month average, which stood at 92 deals, although the average deal value during the same timeframe, from September 2023 to August 2024, was much higher at $17.7 billion.

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Discover the mentor in you!

pharmaphorum

Learn how Oliver Stohlmann nurtures the mentor in you, emphasising values like integrity. Discover how you can become a mentor and make a difference in someone's life.

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Intellia starts late-stage test of CRISPR therapy for rare swelling disease

BioPharma Dive

The study, of Intellia’s treatment for hereditary angioedema, is the second Phase 3 trial the biotech has begun testing its “in vivo” gene editing medicines.

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AZ extends cardiovascular pipeline with $2bn CSPC deal

pharmaphorum

AstraZeneca pays $100m upfront for rights to an oral lipoprotein(a) drug developed by Chinese biotech CSPC Pharmaceutical.

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Scottish patients first in UK to access new lung cancer treatment

Pharma Times

Scottish Medicines Consortium recommends pembrolizumab

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