Tue.Aug 20, 2024

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Opinion: Mask bans disenfranchise millions of Americans with disabilities

STAT

Last week, a mask ban in Nassau County, New York was signed into law. If I lived just 60 miles east of my New Jersey town, I would be under threat of a fine or jail time every time I left the house. I’ve been masking consistently in public since 2020, when the Covid-19 pandemic began, because I have a kidney transplant and will take immunosuppressant medication for the rest of my life.

Hospitals 364
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23andMe inches closes to cancer immunotherapy, guided by its genetic database

PharmaVoice

Dr. Jennifer Low, head of 23andMe’s therapeutics division, is taking the company into new territory with a potential cancer treatment that targets a unique pathway.

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STAT+: Lilly’s Zepbound slashed risk of developing diabetes

STAT

Eli Lilly’s obesity drug Zepbound significantly cut the risk of developing type 2 diabetes, showing the benefits of long-term use of the blockbuster therapy. In a Phase 3 trial that lasted over three years, people with pre-diabetes taking Zepbound had a 93% lower risk of progressing to diabetes compared with people on placebo, Lilly said Tuesday.

Diabetes 363
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Top 20 biopharmas’ market cap up 4.3% in Q2 2024 as GLP-1 drug innovators hold top spots

Pharmaceutical Technology

The top 20 biopharmaceutical companies demonstrated resilience during the second quarter (Q2) of 2024 as global markets and investor optimism improved with anticipation of a potential interest rate cut from the US Federal Reserve.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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STAT+: Congressional probe questions clinical trials run in China, citing Army involvement

STAT

A House committee is investigating whether brand drug companies are collaborating with the Chinese military when they run clinical trials in that country.  “For over a decade, it appears that U.S. biopharmaceutical companies conducted clinical trials with China’s military organizations, and specifically with medical centers and hospitals affiliated with the People’s Liberation Army’s,” according to an Aug. 19 letter that the House China committee sent to t

Hospitals 347
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Isolation room and PPE required for suspected mpox

The Pharmacist

The UK Health Security Agency (UKHSA) has released guidance for primary care settings including using personal protective equipment (PPE) and isolating patients with suspected mpox in a closed room. But the Pharmacists' Defence Association (PDA) has called for additional, specific support and guidance on how community pharmacies should deal with suspected mpox cases.

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Granules India receives ANDA approval for Glycopyrrolate Oral Solution

Express Pharma

Granules India announced that the US Food and Drug Administration (FDA) has approved its Abbreviated New Drug Application (ANDA) for Glycopyrrolate Oral Solution 1mg/5mL filed by Granules Pharmaceuticals, a wholly owned foreign subsidiary of the Company. It is bioequivalent and therapeutically equivalent to the reference listed drug, Cuvposa Oral Solution, 1 mg/5 mL of Merz Pharmaceuticals Glycopyrrolate Oral Solution is an anticholinergic medication indicated for pediatric patients aged three t

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STAT+: What to know about Alnylam’s upcoming readout on its heart drug 

STAT

Next week, the biopharma world will see eagerly awaited results from a trial that could shape care for patients with an increasingly common heart condition — and determine which companies stand to reap billions.  The trial of vutrisiran, from Alnylam Pharmaceuticals, was already announced as positive , with the drug successfully cutting the risk of death and cardiovascular complications in patients with the disease, called transthyretin amyloid cardiomyopathy, or ATTR-CM.

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Lilly’s tirzepatide cuts diabetes risk, study data show

BioPharma Dive

Treatment with the GLP-1 drug, which Lilly sells as Mounjaro and Zepbound, lowered the risk of Type 2 diabetes progression by 94% versus placebo.

Diabetes 113
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Teamwork is good for science — but maybe not for young researchers’ careers

STAT

Science is a team sport, and those teams are getting larger. While that expansion might help researchers answer complex biomedical questions by working together, a recent study suggests that this trend has hampered the career prospects of Ph.D. graduates. The authors analyzed 40 years of data from a National Science Foundation survey that tracks Ph.D. graduates.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Pharma CMO M&A activity shifts focus to scaling in 2023: GlobalData

Express Pharma

Merger and acquisition (M&A) activity in the pharmaceutical contract manufacturing industry declined in 2023 compared to 2021-22. High inflation and interest rates along with an uncertain business environment disincentivised investment. Despite fewer deals, the focus shifted towards scaling operations rather than acquiring specialised capabilities, according to GlobalData.

Vaccines 104
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STAT+: Q&A: How the FDA could use AI for drug and device safety surveillance

STAT

The Food and Drug Administration’s responsibilities don’t end when a drug hits the market after it’s approved: the agency is also continuously assessing products after they’re widely available for any safety issues. And a group of researchers — including two from the FDA’s Center for Drug Evaluation and Research — think artificial intelligence could uncover more signs of these issues, including from electronic health records, social media posts, a

Labelling 350
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CDK9 inhibitors: Disrupting cancer cell growth and the treatment paradigm

pharmaphorum

Learn about the exciting potential of CDK9 inhibitors in disrupting cancer cell growth and changing the treatment landscape for cancer patients. Stay updated on the latest research and developments in this promising field.

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Abortion rights and drug pricing program take spotlight at first night of DNC

STAT

You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine.  Sign up here  to receive it in your inbox on Tuesdays and Thursdays. Hello and happy Tuesday! Our intrepid First Opinion editor Torie Bosch is back, and she has some big ideas for the section in the coming months.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Expert says supplies of mpox vaccine unlikely to suffice

pharmaphorum

Emergent BioSolutions has agreed to donate 50,000 doses of its mpox vaccine for use in the current outbreak, but an expert has warned supplies are unlikely to meet demand

Vaccines 107
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STAT+: Pharmalittle: We’re reading about Zepbound trial results, an Alnylam heart drug, and more

STAT

Rise and shine, everyone, another busy day is on the way. We can tell because the pace of motor vehicles passing by our window is picking up and the official mascots are busy foraging for their breakfast on the campus grounds. As for us, we are engaged in the usual ritual of brewing cups of stimulation. Our choice today is maple bourbon. Yes, this is real.

Diabetes 280
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Agilisium recognised as a leader in Everest Group life sciences digital services for mid-market enterprises PEAK matrix report

Express Pharma

Agilisium, a digital innovations partner for Life Sciences companies, announced that it has been chosen as a leader by the Everest Group in their Life Sciences Digital Services for Mid-Market Enterprises PEAK Matrix Assessment report, 2024. The assessment study involved the evaluation of the vision, capability (strategy, scope of services, innovation, delivery footprint), and market impact (market adoption, portfolio mix, and value delivered) of over 26 niche providers and their range of offerin

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Opinion: Improving the FDA-EMA parallel scientific advice program to advance complex generics

STAT

Off-patent medicines provide people with access to high-quality essential treatment options that can be significantly less expensive than branded on-patent medicines. Off-patent therapies — generics and biosimilars — represent a system-critical industry that delivers around 80% of medicines used worldwide at a fraction of the cost of branded medicines.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Drug delivery method can improve fungal infection treatment

Express Pharma

A unique method developed for drug delivery can prove useful to patients suffering from asthma, cystic fibrosis, previous lung disease, human immunodeficiency virus (HIV), cancer, or those exposed to corticosteroid medications for an extended duration. Nanoparticles are promising for the controlled and effective release of drugs. The use of polymeric nanoparticles is the most advanced method of drug delivery.

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Carbon Health founder steps back from top role, Kaiser hospitals roll out AI scribe

STAT

You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences.  Sign up to get it  delivered in your inbox every Tuesday and Thursday. Carbon Health founder steps back from top role Carbon Health ‘ s chief executive and co-founder  Eren Bali is taking a step back from the primary care tech company, returning instead to the education company Udemy  he co-founded as its chief technology office

Hospitals 267
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Lilly says tirzepatide staves off diabetes in phase 3 trial

pharmaphorum

Eli Lilly's latest clinical readout for dual GIP/GLP-1 agonist tirzepatide is a big one, with data suggesting the drug can reduce the risk of developing type 2 diabetes in overweight and obese adults with pre-diabetes.There's plenty of evidence to show that prediabetes – a higher-than-normal blood sugar level resulting from a level of insulin resistance that isn't high enough to be considered full-blown diabetes – can be reversed if patients commit to an intensive regimen of dietary restriction

Diabetes 106
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Ayvakit's explosive 185% revenue growth: A game-changer in rare disease treatment

Outsourcing Pharma

Ayvakit, a groundbreaking therapy developed by Blueprint Medicines, has witnessed a remarkable 185% year-over-year revenue growth in the second quarter of this year (2024).

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Adcendo licenses Multitude anti-TF ADC in $1bn+ deal

pharmaphorum

Danish biotech Adcendo has accelerated its progression to a clinical-stage biotech by licensing an antibody-drug conjugate (ADC) from China's Multitude Therapeutics with potential in various forms of cancer.Copenhagen-based Adcendo is paying what is rumours to be tens of millions of dollars in upfront fees for rights to Multitude's anti-tissue factor (TF) ADC AMT-754 – now renamed ADCE-T02 – outside mainland China, Hong Kong, Macau, and Taiwan.

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Bavarian Nordic readies 2 million vaccine doses to fight mpox outbreak

Outsourcing Pharma

The Danish company Bavarian Nordic plans to supply up to 2 million vaccine doses this year in response to the World Health Organizationâs declaration of mpox as a Public Health Emergency of International Concern (PHEIC) earlier this month.

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GSK bags breakthrough status for B7-H3 ADC for lung cancer

pharmaphorum

GSK gets FDA breakthrough status for its B7-H3 directed ADC, licensed from Hansah Pharma in a $1.

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Pfizer and BioNTech provide update on mRNA-based combination vaccine program against influenza and COVID-19 in individuals 18-64 years of age

World Pharma News

Pfizer Inc. (NYSE: PFE, "Pfizer") and BioNTech SE (Nasdaq: BNTX, "BioNTech") announced top-line results from their Phase 3 clinical trial to evaluate the companies' combined mRNA vaccine candidate against influenza and COVID-19 in healthy individuals 18-64 years of age. The combination candidate consists of Pfizer's mRNA-based influenza vaccine candidate with the companies' licensed COVID-19 vaccine.

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Buoyed by muscular dystrophy data, Avidity raises $345m

pharmaphorum

Avidity Bio raises $345m from its second big public offering of 2024, after reporting encouraging Duchenne muscular dystrophy data.

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Chronic Care Management: How Your Pharmacy Can Support Patients for the Long Haul

PioneerRx

Chronic conditions make up the bulk of your pharmacy work. Patients with chronic conditions need certain medications for the rest of their lives to achieve a.

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Emergent joins mpox fight with 50,000 vaccine dose donation to Africa

Pharmaceutical Technology

Supplies of Emergent’s smallpox vaccine ACAM2000 will accompany Bavarian Nordic’s vaccine to African countries.

Vaccines 105
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eXmoor pharma’s manufacturing facility receives licence from MHRA

Pharma Times

The company’s Cell & Gene Therapy Centre can now offer a full range of GMP services

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Gilead's Livdelzi granted accelerated FDA approval for primary biliary cholangitis

Outsourcing Pharma

Gilead Sciences, Inc. has announced that the US Food and Drug Administration (FDA) has granted accelerated approval for Livdelzi (seladelpar) for the treatment of primary biliary cholangitis (PBC), a rare and chronic autoimmune disease affecting the bile ducts.

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Changing Faces – Pharma and Biotech July 2024

pharmaphorum

Discover the latest news and updates on AbbVie, Sitryx, DiogenX, and more in the pharmaceutical and biotech industry in July 2024 with Changing Faces. Stay informed with the latest developments.

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