Mon.Nov 13, 2023

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Life expectancy for men in U.S. falls to 73 years — six years less than for women, per study

STAT

The life expectancy of men in the U.S. is nearly six years shorter than that of women, according to new research published on Monday in JAMA Internal Medicine. At least partially as a consequence of over 1 million Covid-19 deaths, life expectancy in the U.S. has declined significantly over the past few years, falling from 78.8 years in 2019 to 77 in 2020 and 76.1 in 2022 — undoing over two decades of progress.

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Humans can’t shake the mosquito threat. Here’s what pharma has in the pipeline.

PharmaVoice

The arsenal against the world’s deadliest creature is growing and a universal vaccine is in the works.

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Study suggests Covid rebound is far more common with Paxlovid than without

STAT

A small and preliminary study published Monday seems to indicate that patients receiving the drug Paxlovid are far more likely to experience Covid rebound than those who did not take it. That conclusion runs counter to previous statements by Pfizer, which makes Paxlovid, and by researchers at the Food and Drug Administration who have argued that while it is not uncommon for people with Covid to have symptoms reemerge after they seem to have recovered, it is not clear that Paxlovid increases the

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SAEM Clinical Images Series: More Than Skin Deep

ALiEM - Pharm Pearls

A 57-year-old female college counselor living in the northeastern United States with no PMH presented for evaluation of rash, joint pain, and dyspnea for the past three weeks. The patient first noticed the rash on her upper back, describing it as being itchy. The rash then spread to her face, scalp, and thighs. Two weeks ago, she noticed swelling in her hands and had a gradual onset of dyspnea on exertion.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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AMA urges coverage of obesity treatments as payers balk at costs

STAT

WASHINGTON – The American Medical Association called on insurance companies, employers, and government programs to cover obesity treatments even as many remain reluctant to pay for them, fearing the costs of covering the drugs at a mass scale. The large physicians’ lobbying group voted to pass a resolution at the association’s interim meeting Monday saying it will “urge all payers to ensure coverage parity for evidence-based treatment of obesity, including FDA- approv

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Where old pathways to innovative cancer care fall short, a new model emerges

pharmaphorum

Where old pathways to innovative cancer care fall short, a new model emerges Mike.

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Optimizing KOL engagement and technology utilization in 2024

PharmaVoice

What if your advisory solution was a skillful blend of innovative tech, medical communications specialists, high-touch client service, and a flexible contract?

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NYU radiologists tackle the challenge of making MRI machines less expensive

STAT

How many radiologists does it take to build a working MRI from scratch? New York University radiologists Leeor Alon and Tobias Block wanted to find out. The two hosted 50 researchers in New York City last month, and over the course of five days, managed to build a small, low-field MRI. Alon and Block are currently fine-tuning its imaging abilities. The overarching message of the gathering: MRIs don’t need to be as expensive as they currently are.

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Anthos blood thinner bests Xarelto on safety in mid-stage study

BioPharma Dive

Trial results add to evidence that so-called Factor XIa inhibitors could have less bleeding risk than currently available oral anticoagulants like Xarelto.

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STAT+: Eli Lilly’s chief scientist on new obesity drug data, gene editing, and a potential new heart drug

STAT

PHILADELPHIA — In a sense, the annual meeting of the American Heart Association wasn’t a huge one for Eli Lilly. Its biggest news was about a very early study of a drug to lower blood levels Lp(a), a protein related to cholesterol that is mainly being watched by lipidologists and drug company analysts. But in another way, the future of Lilly, now the biggest drug company by market capitalization, hung in the balance.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Victoria Atkins replaces Barclay as UK health secretary

pharmaphorum

Victoria Atkins replaces Barclay as UK health secretary Phil.

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STAT+: Novo Nordisk wants to be a cardiovascular company, too, with sights set on inflammation

STAT

PHILADELPHIA – Novo Nordisk, which has dominated the diabetes and obesity markets with its blockbuster drugs Ozempic and Wegovy, now also wants to be a major player in heart disease. The landmark Select trial presented over the weekend – which showed Wegovy significantly cut the risk of heart complications – is just one of many efforts by the Danish drugmaker to expand into the cardiovascular space.

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Ajinomoto spices up its biopharma business with gene therapy deal

BioPharma Dive

Forge Biologics operates a contract manufacturing business as well as develops its own gene therapies, which appears to have attracted the Japan-based food and biotechnology company.

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STAT+: Michigan bill that would pare back pharma liability shield law moves closer to enactment

STAT

A one-of-a-kind law in Michigan that prevents the state government and residents from suing pharmaceutical companies over injuries caused by their medicines is poised to be pared back. A bill designed to allow product liability lawsuits to be filed against drug companies passed the Michigan Senate last month and then passed the House last week. The legislation , which won overwhelming majorities in both chambers but was opposed by the Michigan Chamber of Commerce and a pharmaceutical industry tr

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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UCB on course for approval of gMG drug Rystiggo in EU

pharmaphorum

UCB on course for approval of gMG drug Rystiggo in EU Phil.

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STAT+: Patients loved Carbon Health’s diabetes program. That couldn’t save it

STAT

A diabetes diagnosis was not what Jason had in mind when he set out on a cross-country road trip with his family in the fall of 2021. He had been heavy since he was a kid, but he always had felt pretty healthy — until getting home to the San Francisco Bay Area, when he started to notice his body doing strange things. “It kind of came out of nowhere,” said Jason, who asked to keep his last name private.

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ADCs shine at ESMO ’23, as pharma makes case for early immunotherapy interventions

pharmaphorum

ADCs shine at ESMO ’23, as pharma makes case for early immunotherapy interventions Mike.

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Opinion: Congress must reauthorize the National Advisory Committee for Seniors and Disasters

STAT

With the election of Rep. Mike Johnson as speaker of the House, the urgent and important work of passing appropriations and vital national security legislation is now advancing. But it is also the time to address additional important issues affecting the well-being of Americans, such as one highlighted during the Covid-19 pandemic as well as recent wildfires and hurricanes: the care and support for America’s most vulnerable.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Equity for Women in Healthcare: 131 Years is Too Long to Wait

PharmExec

Closing the gender gap in pharma—and how we get there together.

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These are the need-to-know biotech stories from this weekend

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Lots of news on the cardiovascular front this morning: We discuss Novo Nordisk’s plans in heart disease, and Verve’s gene editing therapy for familial hypercholesterolemia. We also learn about a new initiative to try and prevent gonorrhea spread with a meningitis vaccine.

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Adaptive manufacturing transforms the medical device assembly

Express Pharma

In the ever-evolving landscape of medical device assembly, innovation knows no boundaries. Leaders in medical device assembly are pioneering solutions with unprecedented capabilities to produce multiple product types, facilitating small-batch flexibility without compromising on productivity. This represents a significant shift towards the utilisation of machines that can adapt, acknowledged as adaptive machines, and excel in performance with dynamic changes in manufacturing processes and consume

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Is there a bigger move being planned at Cigna?

STAT

You’re reading the web version of Health Care Inc.,  STAT’s weekly newsletter  following the flow of money in medicine.  Sign up  to get it in your inbox every Monday.  The crushing weight of ambulance bills Over the summer, Precious Mae Clark (in the photo above) emailed me with a desperate plea: She was staring down the barrel of a $7,370 (I repeat, $7,370!

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FDA grants orphan drug designation to MAIA’s glioblastoma agent  

Pharmaceutical Technology

As per the company, the candidate THIO, is the only direct telomere-targeting agent currently in clinical development.

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STAT+: Pharmalittle: Wegovy cuts heart attack risk in milestone trial; AstraZeneca prioritizes U.S. for RSV drug amid surge

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so familiar routine of online calls, meetings, and deadlines has predictably returned. But what can you do? The world, such as it is, continues to spin. To nudge it in a better direction, we are firing up the coffee kettle to brew another cup of stimulation.

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Novel siRNA therapeutic could lower cardiovascular disease risk

European Pharmaceutical Review

A single dose of lepodisiran, a small interfering RNA ( siRNA ) therapeutic, produced over 94 percent reductions in blood levels of lipoprotein(a), also known as Lp(a), with the results lasting for nearly a year, findings from a Phase I trial show. Lepodisiran Lepodisiran is a siRNA therapeutic that blocks the messenger RNA needed to manufacture a key component of lipoprotein(a) in the liver.

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STAT+: Former MIT biologist, who lost positions after engaging in a prohibited sexual relationship, accepts new science position in Prague

STAT

Former MIT and Whitehead Institute star biologist David Sabatini, who lost his positions after he was accused of violating sexual harassment policies in 2021, is resuming his science career, taking a post at a Czech research institute in Prague. Sabatini, of Cambridge, confirmed in a phone call from Prague that he has accepted a position as a “senior group leader” at the Institute of Organic Chemistry and Biochemistry, known as IOCB Prague.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Akili says OTC switch for ADHD DTx leads to sales rise

pharmaphorum

Akili says OTC switch for ADHD DTx leads to sales rise Phil.

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Real-world evidence in pharmaceutical drug development – faster, safer and more relevant?

BioPharma Dive

Regulatory agencies have set the framework and use cases for RWE. How can these increase the probability of success or efficiency in a pre-clinical and clinical drug development program?

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Could GSK myelofibrosis treatment gain EU-first approval?

European Pharmaceutical Review

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion for GSK’s momelotinib, recommending marketing approval. The Committee deemed it beneficial as a treatment for disease-related splenomegaly (enlarged spleen) or symptoms in adults with moderate to severe anaemia who have primary myelofibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis and who are Janus kinase (JAK) inhibitor n

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8 Ways to Prepare for the ABIM Nephrology Certification Exam

Board Vitals - Pharmacist

The American Board of Internal Medicine (ABIM) Nephrology Certification Exam is a critical step for physicians looking to specialize in nephrology. This rigorous examination assesses a candidate’s knowledge and clinical skills in the field of nephrology, making adequate preparation essential. In this blog post, we will outline a comprehensive strategy to help you prepare effectively and increase your chances of passing the ABIM Nephrology Certification Exam.

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CHMP backs GSK’s momelotinib for myelofibrosis

pharmaphorum

CHMP backs GSK’s momelotinib for myelofibrosis Phil.

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