Thu.May 30, 2024

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A third U.S. farm worker infected with bird flu is the first to experience respiratory symptoms

STAT

A third human case of H5 bird flu tied to the ongoing U.S. outbreak in cattle has been detected in a farm worker in Michigan, state health authorities confirmed on Thursday. The unnamed individual worked on a dairy farm and was in close contact with infected cows, the state health department said in a statement. The farm involved is different from the one where an earlier human case was detected last week.

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As Senate’s gaze lands on patents, a former US PTO chief calls the effort a ‘broad misunderstanding’

PharmaVoice

To lower drug prices, lawmakers are turning to the drug patent system to outlaw some common practices — but a former patent agency director says it’s the wrong way to go.

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STAT+: Many docs who tweeted product endorsements also took money from manufacturers, analysis shows

STAT

Most physicians who endorsed a prescription drug or medical device on X — formerly known as Twitter — also received payments from the manufacturers of these products, according to a new analysis that highlights ongoing concerns about financial ties between doctors and industry. The study found 26 of 28 physicians, or 93%, received at least one payment, and the average was more than $27,400 for such things as food and beverages, speaking, consulting, or travel.

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Mythic Therapeutics aims overcome one of ADC’s long-standing challenges

PharmaVoice

By developing ADCs that bind more directly to the target, Mythic Therapeutics believes its technology could deliver a step change for efficacy and safety.

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From Payroll Pains to Growth Gains: Streamlining Payroll & HR for Success

Speaker: Joe Sharpe and James Carlson

In the world of small business management, the challenge of managing payroll & HR efficiently while scaling operations can be overwhelming. Yet, with the right strategies in place, these challenges can become opportunities for growth and innovation. In this session, Joe Sharpe, Senior Director of Managed Payroll Services at IRIS, will reveal practical methods and expert insights for outsourcing and streamlining payroll processes, resulting in substantial time and resource savings.

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STAT+: Did Sarepta Therapeutics earn $4 billion from exon-skipping drugs that don’t work?

STAT

This is the online edition of Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up here  to get it delivered every Thursday to their inbox. There is now a drug on the U.S. market, approved this week, called Bkemv. I’m not kidding. I wish I were. I’m flying to Chicago today for the ASCO meeting.

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Pharmacy funding falls amid increases for GP practices and hospitals, says think tank

The Pharmacist

NHS spending on community pharmacy and ophthalmic services has been reduced by 19.9% since 2016/17, when real-terms funding is adjusted for need, according to new analysis from the Nuffield Trust. But in the same time period, GP primary care services saw a 10.3% increase in real-terms needs-adjusted NHS funding, while funding for acute care in […] The post Pharmacy funding falls amid increases for GP practices and hospitals, says think tank appeared first on The Pharmacist.

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Interview: Has Cybin hit the biggest breakthrough in 40 years to treat psychiatric disorders?

Outsourcing Pharma

In an intriguing interview with Cybinâs CEO, Doug Drysdale, OSP senior editor, Liza Laws found out how second-generation psychedelics could be the biggest breakthrough in psychiatry in 40 years.

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STAT+: Ultragenyx gene therapy for rare liver ailment succeeds in late-stage trial

STAT

Ultragenyx said Thursday afternoon that its gene therapy for a rare liver ailment, glycogen disease type 1A, succeeded in a Phase 3 trial, setting up a potential approval. Patients with GSD1a, as the condition is often known, have a genetic mutation that prevents them from adequately maintaining blood sugar levels. Once considered fatal, GSD1a can now be controlled with regular doses of cornstarch.

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COVID-19 vaccinations now ‘alarmingly low’ in Europe

pharmaphorum

COVID-19 vaccination rates have fallen precipitously in Europe and should be ramped up this autumn so they are at least in line with influenza vaccine uptake.

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STAT+: Novartis sues Maryland over the role of contract pharmacies in a U.S. drug discount program

STAT

Novartis has filed a lawsuit seeking to block a Maryland law that requires the company to ship its medicines to any pharmacy working with hospitals participating in a controversial U.S. government drug discount program. The drugmaker maintained that the state law , which goes into effect on July 1, improperly forces pharmaceutical companies to supply so-called contract pharmacies as part of the discount program known as 340B, according to the lawsuit filed in federal court.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Short reads, big impact: How genomics is revolutionising cancer research

pharmaphorum

Discover how genomics is transforming cancer research through the study of DNA, RNA, and ctDNA. Learn about the latest breakthroughs in the field in this insightful short read.

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Biohaven’s autoimmune drug disappoints, and other biotech news updates from the week

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. A big welcome to everyone coming to Chicago for ASCO this weekend. Say hi if you’re attending our  STAT event  on Friday night!

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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

Polypharmacy, or the concurrent use of at least five medications, can be essential for individuals with multiple chronic conditions. When medications are prescribed with clear therapeutic objectives, optimized to minimize adverse drug reactions (ADRs), and the patient adheres to the regimen, polypharmacy can be appropriate and beneficial. However, it often becomes excessive and hazardous when medications are unnecessary, fail to meet therapeutic goals, pose a high risk of ADRs, or when the patie

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STAT+: Pharmalittle: We’re reading about a deal for a Moderna bird flu shot, NIH trial shortcomings, and more

STAT

Rise and shine, everyone, another busy day is on the way. We can tell because countless birds are chirping outside our window, the pace of motor vehicles passing by is picking up, and the official mascots are busy foraging for snacks on the campus. As for us, we are engaged in the usual ritual of brewing cups of stimulation. Our choice today is orange cream.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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GP referrals 'key' to Pharmacy First success, analysis suggests

The Pharmacist

Referrals from GP practices and NHS services are ‘key’ to the success of Pharmacy First, the Company Chemists' Association (CCA) has suggested, following its analysis of Pharmacy First consultations around the country. Latest analysis of the number of Pharmacy First consultations in CCA pharmacies across England has suggested disparity between the success of the service […] The post GP referrals 'key' to Pharmacy First success, analysis suggests appeared first on The Pharmacist.

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Listen: An ASCO preview & another Duchenne trial failure

STAT

Which presentations are worth catching at ASCO this weekend? What is exon-skipping? And how do you pronounce bronchiectasis? This week on “The Readout LOUD,” we preview some of the research that will be presented at the American Society of Clinical Oncology conference in Chicago. We also discuss the latest news in the health and life sciences, including a milestone in lung disease R&D and a Duchenne muscular dystrophy confirmatory trial failure.

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US Congress passes bill to end Parkinson’s disease

pharmaphorum

The US Congress has passed the first-ever federal bill dedicated to ending Parkinson’s disease, modelled on similar legislation for Alzheimer’s enacted in 2011

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Neurology remains key therapeutic area for Japan pharma majors: GlobalData

Express Pharma

In the dynamic landscape of healthcare, key neurological disorders like Alzheimer’s disease, epilepsy, Parkinson’s disease, and depression pose significant challenges, particularly in the Asia-Pacific (APAC) region, where prevalence is high. The World Health Organization stated in March 2024 that “over 80 per cent of neurological deaths and health losses occur in low- and middle-income countries, and access to treatment varies widely.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacies told to plan for October start for autumn Covid jabs

The Pharmacist

NHS England has told community pharmacies providing Covid vaccinations to plan for an ‘early October’ start to the autumn vaccination programme, in a letter published today. It said that it will agree a precise start date for both the flu and Covid jab campaigns ‘in due course’. And with advice from the Joint Committee on […] The post Pharmacies told to plan for October start for autumn Covid jabs appeared first on The Pharmacist.

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Innovative nanocage promises sustainable cancer drug delivery

European Pharmaceutical Review

A novel drug delivery method combining proline and metal such as palladium, could enable chemotherapy drugs to be transported in the body via nano-sized cages. Practically, this could enable delivering the structure “more directly” to a tumour, while “shielding healthy cells”. Chemotherapy drugs, antibiotics, as well as antivirals could be transported using this delivery system , the authors theorised.

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OTC medicines should be free for people on low incomes through Pharmacy First, say MPs

The Pharmacist

Over the counter (OTC) medications should be made available for free for people on low incomes as part of the Pharmacy First service in England, an influential group of MPs has suggested. The recommendation came as part of the Health and Social Care (HSCC)’s report, published this week following its pharmacy inquiry. The committee said […] The post OTC medicines should be free for people on low incomes through Pharmacy First, say MPs appeared first on The Pharmacist.

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Ophthalmology acquisition to advance tri-specific antibody

European Pharmaceutical Review

Merck (known as MSD outside of the US and Canada) plans to acquire Eyebiotech Limited, with the aim to advance development of novel treatments for vision disorders. The deal has a potential value of $3 billion. Under the terms of the acquisition, Merck, through a subsidiary, will acquire all outstanding shares of EyeBio. The total sum comprises of a $1.3 billion upfront payment and up to $1.7 billion in future milestone payments. the acquisition significantly expands Merck/MSD’s presence in oph

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First patient gets bowel cancer jab in NHS 'matchmaker' push

pharmaphorum

The first patient has received a BioNTech colorectal cancer vaccine as part of the NHS Cancer Vaccine Launch Pad (CVLP) 'matchmaker' service

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Researchers identify genetic changes responsible for rare childhood immune disorders

Pharma Times

Affecting the immune system, various forms of SCID are estimated to affect one in 75,000 to 100,000 newborns

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New patent for Corcept Therap drug KORLYM

Drug Patent Watch

Annual Drug Patent Expirations for KORLYM Korlym is a drug marketed by Corcept Therap and is included in one NDA. It is available from one supplier.

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NHS England funds new PCN community pharmacy engagement roles

The Pharmacist

Funding has been announced for new community pharmacy PCN engagement lead roles to support the implementation of the access recovery plan. The role will be the point of contact between community pharmacies and general practices within PCNs. It will be expected to support the implementation of the Pharmacy First service, expanded blood pressure checks service and the […] The post NHS England funds new PCN community pharmacy engagement roles appeared first on The Pharmacist.

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FDA approves Teva Pharmaceuticals’ AUSTEDO XR for TD and HD chorea

Pharmaceutical Technology

The US FDA approved Teva Pharmaceuticals’ AUSTEDO XR as a once-daily treatment option for tardive dyskinesia and Huntington’s disease chorea.

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The Impact of Serialization Technology: Ensuring Product Integrity and Regulatory Compliance

Pharmaceutical Commerce

These advancements continue to act as a key driver in helping to boost the security, efficiency, and innovation of global industries, include pharma.

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NHS announces hospitals will roll out ‘Martha’s Rule’ as part of patient safety initiative

Pharma Times

The first phase of the programme will be in place in hospitals across the UK by March 2025

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Alembic announces USFDA approval for Sacubitril and Valsartan tablets

Express Pharma

Alembic Pharmaceuticals announced that it has received final approval from the US Food & Drug Administration (USFDA) for its Abbreviated New Drug Application (ANDA) for Sacubitril and Valsartan Tablets, 24 mg/26 mg, 49 mg/51 mg, and 97 mg/103 mg. The approved ANDA is therapeutically equivalent to the reference listed drug product (RLD), Entresto Tablets, 24 mg/26 mg, 49 mg/51 mg, and 97 mg/103 mg, of Novartis Pharmaceuticals.

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J&J shares data on would-be blockbuster antidepressant

pharmaphorum

Johnson & Johnson's seltorexant hits the mark in a phase 3 trial involving patients with depression and sleep disturbances

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Asahi Kasei's $1.1 billion power move - acquiring Calliditas to dominate global healthcare

Outsourcing Pharma

In a bold move set to reshape the global healthcare landscape, Asahi Kasei Corp. announced its intent to acquire Swedish drug maker Calliditas Therapeutics AB through a voluntary tender offer.

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BlueRock Therapeutics receives FDA Regenerative Medicine Advanced Therapy designation for Parkinson’s disease cell therapy candidate bemdaneprocel

World Pharma News

Bayer AG and BlueRock Therapeutics LP, a clinical stage cell therapy company and wholly owned independently operated subsidiary of Bayer AG, announced today that BlueRock's investigational cell therapy bemdaneprocel for the treatment of Parkinson's disease has been granted Regenerative Medicine Advanced Therapy (RMAT) designation from the U.S. Food and Drug Administration (FDA).

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