Sat.Dec 07, 2024

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Exploring Opportunities for LNP Delivery in mRNA

PharmaTech

LNPs have gained solid ground as a drug delivery system for mRNA due to their success in the vaccines arena.

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Blinatumomab Plus Chemotherapy Improves DFS in Pediatric Patients With SR B-ALL

Pharmacy Times

In newly diagnosed average and high standard risk B-cell acute lymphoblastic leukemia (B-ALL), blinatumomab improved disease-free survival (DFS) by approximately 97.5% and 94.1%, respectively.

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Trending Sources

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Sanofi advances a drug for a rare, platelet-destroying disease

STAT

(This roundup of news from the ASH 2024 conference first appeared in STAT’s “ASH in 30” newsletter. To get future editions, sign up here.) Greetings from the always-lovely San Diego. Adam Feuerstein, here, and as you can see from the sunrise photo above, I am still very much on East Coast time. (Nice view from my hotel room, however.

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GLP1 Agonists and Dietary Fiber May Reduce VTE Risk and Improve GVHD Outcomes

Pharmacy Times

Glucagon-like peptide 1 (GLP1) receptor agonists were shown to be associated with a reduced risk of venous thromboembolism (VTE), while high dietary fiber intake was shown to enhance microbiome health, lower graft-versus-host disease (GVHD) severity, and improve overall survival following allogeneic hematopoietic cell transplantation.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Opinion: STAT readers on the value of medical comedy, the pediatrician shortage, and more

STAT

First Opinion is STAT’s platform for interesting, illuminating, and provocative articles about the life sciences writ large, written by biotech insiders, health care workers, researchers, and others. To encourage robust, good-faith discussion about issues raised in First Opinion essays, STAT publishes selected Letters to the Editor received in response to them.

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How does weight loss drug Mounjaro work and why is it in such high demand?

The Guardian - Pharmaceutical Industry

The King Kong of weight loss drugs will be available on the NHS but only patients with most need will get it Mounjaro, known as the King Kong of weight loss drugs, will be available to patients on the NHS, but this week it was announced the medication will be prioritised to people with the highest needs with the rollout expected to extend over 12 years.

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ASH: Cilta-Cel Significantly Increases Minimum Residual Disease Negativity in Lenalidomide-Refractory Multiple Myeloma

Pharmacy Times

Rakesh Popat, MBBS, PhD explains the mechanisms of action behind the improvement in minimum residual disease in patients with lenalidomide-refractory multiple myeloma with cilta-cel compared with standard of care.

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Biocon Announces FDA Approval of Ustekinumab Biosimilar

Big Molecule Watch

On December 1, 2024, Biocon announced that the FDA has approved YESINTEK (ustekinumab-kfce), a biosimilar to J&Js STELARA. YESINTEK is approved for the treatment of Crohns disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis. According to the announcement, Biocon had entered into a settlement and licensing agreement with Janssen to commercialize YESINTEK in the United States no later than February 22, 2025, upon approval from the FDA.

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ASH 2024: Pharmacists Play Key Role in Incorporating Venetoclax, Blinatumomab for Treatment of Hematologic Malignancies

Pharmacy Times

Amir Ali, PharmD, BCOP highlights the success of shorter-treatment duration venetoclax in patients with acute myeloid leukemia and efficacy of pre-transplant blinatumomab in those with acute lymphocytic leukemia.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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ASH Expert: Axi-Cel Treatment Causes Decreased Incidence, Severity of Toxicities in Large B-Cell Lymphoma

Pharmacy Times

Jason Wang, MD highlights the reduction in incidence and severity of adverse events such as cytokine release syndrome and ICANS following axi-cel treatment in patients with R/R LBCL.

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