Mon.Jan 22, 2024

article thumbnail

Why many more people are lining up for a flu shot than a Covid vaccine

STAT

America is over the Covid vaccine. Frantic lineups for scarce doses when Covid vaccines first became available have long since given way to widespread indifference. Each new round of boosters has drawn fewer bared arms than the round before it. The Centers for Disease Control and Prevention estimates that, as of Jan. 6, a mere 21.5% of Americans aged 18 and older and 11% of children have been vaccinated with the latest Covid vaccine.

Vaccines 364
article thumbnail

SAEM Clinical Images Series: Fever with Rash

ALiEM - Pharm Pearls

A 40-year-old male, tailor by occupation, was brought to the Emergency Department with complaints of high-grade fever for the past 11 days. Fever was documented to be 102°F and was not associated with any chills or rigors. The patient also complained of shortness of breath for one week associated with a dry cough, as well as an altered sensorium for one day.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Dana-Farber expands studies to be retracted to 6, plus 31 to be corrected over mishandled data

STAT

A review of alleged data manipulation in studies involving four top scientists at Dana-Farber Cancer Institute has led to plans to retract six papers and correct 31 manuscripts, the institute confirmed on Monday. The news comes as the famed cancer research and treatment center is now reviewing scores of studies co-authored by some of its leading researchers, including CEO Laurie Glimcher, COO William Hahn, and prominent scientists Irene Ghobrial and Kenneth Anderson.

Hospitals 358
article thumbnail

Controversial challenge trials offer unparalleled innovation — with ethical bumps

PharmaVoice

Demand for infectious disease treatments is projected to grow and challenge trials, when done right, could speed drug development.

article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

STAT+: A Harvard course seeks to put food on the table in medical education

STAT

BOSTON — Doctors often don’t have a lot of time to chat with patients during medical appointments — which means that conversations about nutrition can wind up taking a backseat to other concerns. But during a recent weeklong course at Harvard T.H. Chan School of Public Health, preventive cardiologist Stephen Devries enlisted two dozen students in the mission to integrate nutrition into clinical medicine — changing the way medicine is taught and health care is delivere

Diabetes 333
article thumbnail

The hunt for an elusive universal coronavirus vaccine

PharmaVoice

A new study shows that a universal vaccine would lead to huge financial and mortality wins during a pandemic, but development has been slow going.

Vaccines 130

More Trending

article thumbnail

PulmCrit hot take: VAP prophylaxis (PROPHY-VAP trial)

EMCrit Project

background: ANTHARTIC trial Prophylaxis against VAP (ventilator associated pneumonia) has is already supported by a few studies in the literature, perhaps most notably the ANTHARTIC trial. That was a multi-center RCT evaluating 48 hours of therapy with ampicillin-sulbactam for patients intubated following cardiac arrest. Antibiotic therapy reduced early-onset VAP, with a trend towards more ventilator-free […] EMCrit Project by Josh Farkas.

123
123
article thumbnail

STAT+: Gilead’s Trodelvy fails in lung cancer and raises new questions on antibody drug conjugate drugs

STAT

Gilead Sciences said Monday that Trodelvy, its “smart-bomb” medicine that combines an antibody with chemotherapy, did not significantly extend the lives of patients with metastatic non-small cell lung cancer when given after a first treatment failed. The result, from a closely watched study called Evoke-01, will be seen as a disappointment by investors and oncologists alike.

article thumbnail

Wear PPE for suspected measles, pharmacies told

The Pharmacist

Community pharmacies are among the 'most likely' places to encounter a case of measles, NHS England (NHSE) has warned. And staff have been instructed to 'take appropriate action' and wear personal protective equipment (PPE) to 'stop onward transmission without delay', when dealing with patients with suspected measles. This comes as the UK Health Security Agency […] The post Wear PPE for suspected measles, pharmacies told appeared first on The Pharmacist.

article thumbnail

STAT+: In ‘march-in’ rights, some see a tool to lower drug prices. Others see a threat to intellectual property

STAT

In the fall of 2020, Robert Sachs was prescribed a medication to treat prostate cancer that had metastasized into some of his bones. He welcomed the treatment, but was surprised by the $740 monthly copay cost, even after coverage from Medicare and supplemental insurance. So Sachs began reading about the drug, Xtandi , and found the annual list price at the time was about $156,000, or $427 a day, for men with commercial health insurance.

article thumbnail

Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

article thumbnail

Karuna, Cerevel might be just the start of psychiatry drug M&A

BioPharma Dive

New details of the proposed acquisitions show there were multiple interested buyers, which, according to some analysts, could set the stage for more dealmaking.

124
124
article thumbnail

Medicare Advantage update pushes Wall Street to reset expectations

STAT

You’re reading the web version of Health Care Inc.,  STAT’s weekly newsletter  following the flow of money in medicine.  Sign up  to get it in your inbox every Monday.  Summa wrestling for physician buy-in General Catalyst finally has the hospital system it wants. But there’s some skepticism that the venture capital firm will live up to its promises and get the required buy-in from physicians and other medical staff, my colleague Tara Bannow reports.

Hospitals 307
article thumbnail

Gilead ADC medicine misses goal in closely watched lung cancer study

BioPharma Dive

Trodelvy didn’t outperform chemotherapy in a large study of people with a common lung tumor, a setback that sent company shares down by double digits.

article thumbnail

New tool for tracing blood cells’ ancestry might one day help predict disease risk

STAT

The human blood system is in a constant state of turnover. First-line immune defenders, like neutrophils, need to be replaced after just four to eight hours, platelets can last a week, red blood cells up to four months, and some white blood cells, like memory B cells, live for decades. The heroic task of constantly replenishing these ranks, and making sure the balance of different types of blood cells is right, falls to a primitive reserve of stem cells that reside deep in the bone marrow.

article thumbnail

Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

article thumbnail

Obesity care needs greater revolution: GlobalData

Express Pharma

Novo Nordisk and Eli Lilly have been dominating the obesity scene in the past year with the approval of their glucagon-like peptide-1 receptor (GLP-1R) agonists Wegovy and Zepbound. Although medicines with other mechanisms of actions are available on the market, GLP-1R agonists seem to have a greater impact on weight loss and the patient’s life. The development of new weight loss medicines is therefore making great progress, but obesity care needs a much greater revolution, says GlobalData.

110
110
article thumbnail

STAT+: FDA sets aggressive deadline for inspection overhaul

STAT

WASHINGTON — Food and Drug Administration officials hope to finish this year a massive overhaul of the way the agency inspects facilities that make drugs, medical devices, and food products, they said Friday. The reorganization was spurred by the FDA’s mishandling of the infant formula crisis. The agency was slow to inspect a major infant formula plant despite a whistleblower complaint about deadly bacterial contamination at the facility.

article thumbnail

Pharmacists concerned Pharmacy First will raise risk of patient abuse

The Pharmacist

Almost nine in 10 employed and locum pharmacists are concerned over the potential damage Pharmacy First may have on an ‘already fragile’ workforce in England, a survey by the Pharmacists’ Defence Association (PDA) has revealed. ‘Many’ among the more than 3,500 staff surveyed also said they were worried the ‘hurried’ upcoming service launch could put […] The post Pharmacists concerned Pharmacy First will raise risk of patient abuse appeared first on The Pharmacist.

110
110
article thumbnail

Opinion: STAT+: Some countries are moving to digital prescription drug information for patients. The U.S. shouldn’t follow suit

STAT

Getting a new prescription can be overwhelming: medication schedules, foods to eat or avoid, interactions between different drugs. Having all of these details in accessible, printed documents keeps patients informed and mitigates the risk of medication errors. However, there’s a growing movement across the world to eliminate printed medication information, making it harder for patients to learn about the drugs that, in many cases, save their lives.

article thumbnail

Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

article thumbnail

World’s first malaria vaccine rolled out in Cameroon

Express Pharma

Cameroon has kickstarted the world’s first routine vaccine programme against malaria. It is one of 20 African countries planning to introduce the drug this year, according to global vaccine alliance Gavi. The RTS,S malaria vaccine, developed by GSK and sold under the brand name Mosquirix, was backed by the World Health Organization in July 2022.

Vaccines 104
article thumbnail

STAT+: Pharmalittle: We’re reading about Lilly plant problems, FDA reorganization plans, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because now the time has come to dive back in to the usual routine of online meetings, calls, and deadlines. But what can you do? The world, such as it is, continues to spin. So time to give it a nudge in a better direction with a cup or three of stimulation.

232
232
article thumbnail

ANCC vs. AACN: Which AGACNP Exam Should I Take?

Board Vitals - Pharmacist

The American Nurses Credentialing Center (ANCC) and the American Association of Critical Care Nurses (AACN) are the regulatory bodies responsible for conducting exams for individuals aspiring to obtain certification as a nurse practitioner. Both ANCC and AACN certifications serve as proof of the expertise possessed by nurse practitioners. An Adult Gerontology Acute Care Nurse Practitioner (AGACNP) cares for adult patients experiencing acute illness related to a condition.

100
100
article thumbnail

Investigators fault Lilly plant for manufacturing issues

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Today, lots of regulatory content! We talk about march-in rights and chastening TikTok influencers for their prescription drug #sponcon.

article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

Sandoz makes its first post-spinout acquisition

pharmaphorum

Sandoz makes its first acquisition since spinning out of Novartis, buying a Lucentis biosimilar from Coherus that will boost its position in the US market.

article thumbnail

STAT+: Physician buy-in will make or break VC firm General Catalyst’s bold hospital deal

STAT

It makes sense in theory for hospitals and startups to strike deals. Not only would doctors get first dibs on new health care technologies, their organizations would see windfalls if those startups hit it big. In practice, it often doesn’t work out that way. Doctors and other clinicians have their own way of doing things, and they typically don’t take kindly to an administrator telling them to learn a new product, especially if the goal is financial gain.

Hospitals 149
article thumbnail

Optimised method could facilitate analysis of complex biologics

European Pharmaceutical Review

Researchers have developed two capillary electrophoresis (CE)-based analytical methods : capillary zone electrophoresis (CZE) and imaged capillary isoelectric focusing (iCIEF) to analyse a broad spectrum of monoclonal antibodies (mAbs) and complex mAb formats. Charge heterogeneity analysis of mAbs and complex formats, such as bispecifics, is “crucial” for therapeutic applications, according to the researchers.

98
article thumbnail

Legislative Proposals to Tackle Improper Pharmaceutical Patents in the Orange Book

Drug Patent Watch

A recent article published in Health Affairs, delves into the Federal Trade Commission’s (FTC) concerns regarding the inclusion of improper patents in the FDA’s Orange Book by pharmaceutical manufacturers. The… The post Legislative Proposals to Tackle Improper Pharmaceutical Patents in the Orange Book appeared first on DrugPatentWatch - Make Better Decisions.

article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

Next stage in GSK’s Zantac defense gets underway today

pharmaphorum

A hearing will get underway in Delaware later today in the latest phase of GSK’s attempts to defend itself from allegations that its Zantac drug caused cancer in patients.

104
104
article thumbnail

Bladder cancer-focused CG Oncology files for IPO

Pharmaceutical Technology

On 18 January 2024, US-based biotech CG Oncology announced it was looking to raise $200m in an upcoming initial public offering (IPO), which will be the first for the biotech sector in 2024.

94
article thumbnail

Pharma waste management: Balancing cost, compliance, and environmental responsibility

pharmaphorum

Pharma waste management is crucial for balancing cost, compliance, and environmental responsibility in the healthcare industry. Explore strategies and best practices for effectively managing pharmaceutical waste, while ensuring regulatory compliance and minimising environmental impact.

106
106
article thumbnail

NHS catch up campaign launched for missed MMR vaccines

Pharma Times

Approximately one in five children will be hospitalised to treat measles

Vaccines 131
article thumbnail

Trial data raises questions about Imfinzi in liver cancer

pharmaphorum

AstraZeneca’s Imfinzi plus bevacizumab and TACE improved PFS compared to TACE alone in hepatocellular carcinoma patients in EMERALD-1, but more data may be needed before approval

101
101