STAT

SEPTEMBER 8, 2024

News that a person in Missouri contracted H5 bird flu despite having no known contact with infected animals or birds — in other words, no evident route of infection — raises pressing questions public health officials are surely scurrying to answer. The rationale for that urgency is this: An unexplained H5 infection raises the possibility of person-to-person spread of a flu virus that has never before circulated in humans, and to which people would not have immunity.

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BioPharma Dive

SEPTEMBER 8, 2024

Study results provide much-anticipated details to Summit’s claim earlier this year that its drug “decisively beat” Merck’s dominant immunotherapy.

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STAT

SEPTEMBER 8, 2024

SAN DIEGO — For years, Merck’s drug Keytruda has dominated cancer immunotherapy, racking up dozens of approvals, extending the lives of patients, and bringing in billions of dollars to the pharma giant. But detailed data presented by Summit Therapeutics on Sunday demonstrated that the company’s experimental therapy has done what no other has done before: beat Keytruda in a head-to-head late-stage trial in lung cancer.

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pharmaphorum

SEPTEMBER 8, 2024

Results of Ideate-Lung01 trial at WCLC back up MSD and Daiichi Sankyo's decision to move anti-B7-H3 ADC I-Dxd into phase 3 for small cell lung cancer

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STAT

SEPTEMBER 8, 2024

A busy medical student, Vanessa Apea wasn’t her usual energetic self. So she dragged herself to the doctor to get checked and have her blood drawn. A week later, she received a call telling her to return to the clinic; it was urgent. When she arrived, the doctor asked if she had a family history of blood or genetic disorders. Was she having shortness of breath?

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pharmaphorum

SEPTEMBER 8, 2024

CDC reports the first-ever US case of an H5 strain of avian influenza without a known occupational exposure to sick or infected animals

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Pharmacy Joe

SEPTEMBER 8, 2024

In this episode, I’ll discuss the use of phenobarbital in severe alcohol withdrawal. Episode 955: Has Everyone Gotten the Mechanism of Phenobarbital in Alcohol Withdrawal Wrong? Subscribe on iTunes , Android , or Stitcher Severe alcohol withdrawal is a result of both the lack of GABA activity AND over stimulation of glutamate receptors. While benzodiazepines are considered the first-line treatment option, phenobarbital is used as an adjunct and, in recent years, has been studied as a potential m

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Hospitals Inpatient 59

The Guardian - Pharmaceutical Industry

SEPTEMBER 8, 2024

Experts call for more research into ‘off-label’ medications, and supply chain alternatives not driven by profit motive Get our breaking news email , free app or daily news podcast Several crucial medicines for pregnant women are in shortage in Australia because of a “perfect storm”, experts warn, whereby the only drugs registered as safe for pregnancy are old and less profitable to pharmaceutical companies discontinuing their distribution amid manufacturing disruptions since the pandemic.

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Labelling Pharmaceutical Companies Pharmaceutical Companies 60

PharmaTech

SEPTEMBER 8, 2024

Drug stability impacts efficacy and safety. Choosing the right packaging is crucial. This paper outlines key factors affecting stability and provides packaging guidelines.

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Packaging 52

Pharmaceutical Technology

SEPTEMBER 8, 2024

MNV-201 is under clinical development by Minovia Therapeutics and currently in Phase I for Subacute Necrotizing Encephalomyelopathy (Leigh Disease).

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Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

The Honest Apothecary

SEPTEMBER 8, 2024

One of the convictions I had as I began to re-imagine my blog is that it would be an entirely non-monetized form of expression. For some, blogging is actually a source of significant income, and I see nothing wrong with this. For others, writing is a way to drive potential customers to their “paid” product.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Sonidegib phosphate is under clinical development by Sun Pharma Advanced Research and currently in Phase I for Non-Small Cell Lung Cancer.

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The Honest Apothecary

SEPTEMBER 8, 2024

Another important decision I had to make, as I began to re-imagine The Honest Apothecary blog, was about the posting cadence I intend to keep up. To put it in more pharmaceutical terms: What would the dosing frequency be? QD? QOD? PRN? Those are pharmacy shorthand for daily, every other day, or as needed.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

PEP-07 is under clinical development by Sentinel Oncology and currently in Phase I for Refractory Acute Myeloid Leukemia.

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The Honest Apothecary

SEPTEMBER 8, 2024

“So you see Jason,” said the man we’ll call “Steve”, to me as we sipped on our coffees in the cafeteria, “Tonya is a great individual contributor. She knows her job well, better than most.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

PEP-07 is under clinical development by Sentinel Oncology and currently in Phase I for Relapsed Acute Myeloid Leukemia.

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PharmaTech

SEPTEMBER 8, 2024

Insights into molecular behaviors and predictive capabilities are bringing numerous benefits.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Safinamide mesylate is under clinical development by Zambon Co and currently in Phase II for Drug-Induced Dyskinesia.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

The Honest Apothecary

SEPTEMBER 8, 2024

A post on my preference for connections rather than simple comments

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Pharmaceutical Technology

SEPTEMBER 8, 2024

BR-6002 is under clinical development by Boryung Pharmaceutical and currently in Phase I for Cardiovascular Disease.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

PEP-07 is under clinical development by Sentinel Oncology and currently in Phase I for Mantle Cell Lymphoma.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

MNV-201 is under clinical development by Minovia Therapeutics and currently in Phase I for Pearson Syndrome.

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Pharmacy Management

Pharmaceutical Technology

SEPTEMBER 8, 2024

BR-6002 is under clinical development by Boryung Pharmaceutical and currently in Phase I for Gastric Ulcers.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

BR-6002 is under clinical development by Boryung Pharmaceutical and currently in Phase I for Duodenal Ulcer.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Mirdametinib is a small molecule commercialized by SpringWorks Therapeutics, with a leading Pre-Registration program in Neurofibromatoses Type I (Von Recklinghausen's Disease).

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Gedatolisib is a small molecule commercialized by Celcuity, with a leading Phase II program in Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer).

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Interferon alfa-2b is under clinical development by Center for Genetic Engineering and Biotechnology and currently in Phase II for Genital Warts (Condylomata Acuminata).

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Navitoclax dihydrochloride is a small molecule commercialized by AbbVie, with a leading Phase III program in Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF).

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Diazoxide choline CR is a small molecule commercialized by Soleno Therapeutics, with a leading Pre-Registration program in Prader-Willi Syndrome (PWS).

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Eblasakimab is a monoclonal antibody commercialized by Aslan Pharmaceuticals, with a leading Phase II program in Atopic Dermatitis (Atopic Eczema).

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Pharmaceutical Technology

SEPTEMBER 8, 2024

FPI-1434 is a monoclonal antibody conjugated commercialized by Fusion Pharmaceuticals, with a leading Phase II program in Cervical Cancer.

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Pharmaceutical Technology

SEPTEMBER 8, 2024

Chenodiol is under clinical development by Mirum Pharmaceuticals and currently in Pre-Registration for Cerebrotendinous Xanthomatosis.

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