Mon.Nov 06, 2023

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A new study maps the lasting effects of gun violence on children and teens who survive their injuries

STAT

When Christian Pulcini was a pediatric emergency fellow at Children’s Hospital of Philadelphia, he witnessed firsthand the ways that gun violence affected children who survived it. He still remembers one young boy who had been shot in the neck while playing outside his home. Pulcini did not remove the bullet — a routine practice, often safer than removal.

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The thorniest questions facing pharma, according to a leading bioethicist

PharmaVoice

Bioethics guru Arthur Caplan of NYU gives his outspoken and frank opinion on the industry’s minefield of ethical challenges.

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As extreme heat soars, laws to protect outdoor workers are bubbling up — and facing resistance

STAT

As weather starts to cool in much of the country, the heat-baked cement and sweaty afternoons from this summer fade from collective memory. But activists and labor groups representing outdoor workers haven’t forgotten. They are pushing lawmakers and regulators to keep facing the heat. On Tuesday, the Miami-Dade Board of County Commissioners will take a final vote on a proposed heat standard to protect outdoor workers.

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SAEM Clinical Images Series: Wolf in Sheep’s Clothing

ALiEM - Pharm Pearls

A 55-year-old female with a history of hyperlipidemia presents after a syncopal episode. She had mild nausea and diarrhea on the morning of presentation but otherwise had no prodromal symptoms before suddenly losing consciousness in a grocery store. Of note, she recalls a similar syncopal episode in the remote past, also preceded by gastrointestinal symptoms at that time.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: There’s a real risk that harm reduction could be a fad

STAT

Harm reduction is having its moment in America. The doors of drug-related harm reduction have swung wide open after years of federal funding bans. Extensive opioid settlement payouts combined with an urgency to address the overdose crisis have allowed for harm reduction approaches to catch on like wildfire. But as renowned addiction author William White muses, “The fastest way to kill anything in America is to turn it into a superficial fad that dies from distortion and over-exposure.

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Samay’s AI-assisted wearable technology accurately diagnoses COPD

Pharma Times

The device successfully diagnosed COPD in patients with 90% accuracy - News - PharmaTimes

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First high-resolution 3D image offers insight into heart and muscle health

Pharma Times

The image helps researchers understand how heart muscles operate in disease - News - PharmaTimes

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In experiment, electrical stimulation of the spinal cord helps a patient with Parkinson’s to walk

STAT

An experimental treatment that delivers an electrical current to the spinal cord appeared to notably improve the ability of a man with Parkinson’s to keep his balance and walk without freezing up, a development that experts say could be a dramatic advance if it is found to deliver similar benefits in larger studies. The volunteer, identified as Marc, a 62-year-old who has had Parkinson’s for 30 years, spoke on a call with reporters last week.

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The obesity drug effect: What medical device executives are saying

PharmaVoice

Investor concerns that interest in GLP-1s will slow demand for medical devices and procedures have shaved roughly $370 billion in value from stocks across the medtech sector, according to research by Mizuho.

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STAT+: Data backing prescription digital therapeutics found lacking in rigor, inclusivity

STAT

The fast-evolving world of digital therapeutics offers the promise of lowering barriers to accessing health care, but the companies behind these software-based tools face an uphill battle in convincing clinicians and insurers that their products can complement traditional medicine. That debate has largely focused on the quality of evidence backing these prescription digital therapies.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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How over-investment is killing digital health companies

pharmaphorum

How over-investment is killing digital health companies Mike.

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STAT+: Astellas shows enough data for eye treatment to support expanded use, but still lags competitor

STAT

Astellas on Saturday presented study results showing an increased treatment effect over time for its approved medicine for a common type of vision loss. The new data are probably enough to convince the Food and Drug Administration to remove restrictions on the drug’s use, but they still don’t measure up to a competing treatment from Apellis Pharmaceuticals.

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Anthropy23, part one: The future of AI, the future of Britain

pharmaphorum

Anthropy23, part one: The future of AI, the future of Britain Mike.

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STAT+: Government looks to tinker with new caps on Medicare Advantage broker payments

STAT

The federal government is proposing to rein in health insurance companies that entice brokers with lavish bonuses to sell their Medicare Advantage plans by placing a firmer cap on broker compensation. However, even with new guardrails in place, agents and brokers will still have strong financial incentives to move people into Medicare Advantage plans instead of pitching supplemental coverage for the traditional Medicare program.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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PDA sounds alarm over AI use by pharmacy students

The Pharmacist

The Pharmacists’ Defence Association (PDA) has warned pharmacy students that the use of artificial intelligence (AI) technology risks charges of plagiarism and misconduct. In its October 2023 student newsletter, the PDA highlighted a ‘concerning rise’ in the number of students using AI programmes – such as ChatGPT and QuillBot – to write or enhance assessments. […] The post PDA sounds alarm over AI use by pharmacy students appeared first on The Pharmacist.

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STAT+: Ventyx stock craters after lackluster mid-stage trial results for psoriasis drug

STAT

SAN DIEGO — Ventyx Biosciences reported on Monday that it was ending development of an experimental drug for treating plaque psoriasis though it proved safe and moderately effective in a mid-stage trial. Within hours, the company’s stock tanked by more than 80%. That’s because the company announced that the small molecule, VTX958, had not met the biotech’s internal goals to advance to the next phase of clinical development.

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UK patient data project reaches one million volunteers

pharmaphorum

UK patient data project reaches one million volunteers Phil.

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STAT+: Pharmalittle: Pharma trade group slams European Commission proposal; U.S. lawmakers demand FDA explain its approach to shortages

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was somehow relaxing and invigorating, because that oh-so familiar routine of online calls, meetings, and deadlines has predictably returned. But what can you do? The world, such as it is, continues to spin. So time to nudge it in a better direction with a cup or three of stimulation.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Drug combos from AZ, Boehringer show promise in CKD

pharmaphorum

Drug combos from AZ, Boehringer show promise in CKD Phil.

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STAT+: Moonlake’s credibility takes another hit with mid-stage study spin job

STAT

Moonlake Immunotherapeutics, a Swiss biotech, was buried Monday under an avalanche of its own data spin. It’s been awhile since I encountered a management team that speaks so arrogantly about the supposed supremacy of its own drug, but then fails to back up the talk with real data. Moonlake claimed its experimental antibody called sonelokimab delivered “landmark” results in a mid-stage study of psoriatic arthritis.

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Maximizing Intellectual Property Value in the Biomedical Sector: A Case Study on Rucaparib Patents

Drug Patent Watch

A paper titled “Analysis of Strategy for Extending Patent Protection of Rucaparib” by Zhifeng Wang. discusses the strategies employed by pharmaceutical companies to extend the patent protection period of the… The post Maximizing Intellectual Property Value in the Biomedical Sector: A Case Study on Rucaparib Patents appeared first on DrugPatentWatch - Make Better Decisions.

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XBI biotech index rises, giving investors a shred of hope

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Happy Monday. So, we’ve got a welcome bump in the XBI, see that European regulatory conditions are prompting Ozempic maker Novo Nordisk to look stateside for growth, and more.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Drug Diversion in Healthcare is a National Problem, but Recent Survey Shows a Promising Path Forward

PharmExec

Healthcare organizations can lower their risk of drug diversion by strengthening staffing, employee training, and technology.

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Lots of FDA Guidance, But Few Drug Manufacturing “Remote Interactive Evaluations” (We Would Call Them “Virtual Inspections”)

FDA Law Blog: Biosimilars

By Douglas B. Farquhar & Richard A. Lewis, Senior Regulatory Device & Biologics Expert — We were preparing this blogpost about FDA’s draft guidance on “Remote Interactive Evaluations” when we learned something. A phone call to FDA requested information about the number of Remote Interactive Evaluations (RIEs) that FDA has performed at drug manufacturing facilities since it announced in April 2021 that it would start using them as an alternative to on-site inspections.

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Pharmacy Security - How to Safeguard Your Patients and Inventory

PioneerRx

It pays to be safe. Pharmacy security is an understated but essential aspect of pharmacy ownership. Whether you’re stocking medications, testing supplies.

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Global cell line development to surge in next decade

European Pharmaceutical Review

The global cell line development industry is expected to value $4,674.8 million by 2033, according to a report by Future Market Insights. Total cell line product sales are expected to reach $3,124.4 million in 2023, with a predicted compound annual growth rate (CAGR) of 4.1 percent through the next decade. Advancements in biotechnology, pharmaceutical research, and biomanufacturing processes are key factors in driving the market, the author acknowledged.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Increasing Solubility with Zerion Pharma at CPHI Barcelona

PharmaTech

Pharmaceutical Technology Europe® spoke with Ole Wiborg from Zerion Pharma, a Danish pharmaceutical development company, at the inaugural Start-Up Market on the show floor at CPHI Barcelona 2023.

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AAO 2023: intravitreal treatment shows benefit in geographic atrophy

European Pharmaceutical Review

IZERVAY ( avacincaptad pegol intravitreal solution) induced a year-over-year reductions in the rate of geographic atrophy lesion growth in patients with geographic atrophy secondary to age-related macular degeneration (AMD) in a Phase III trial, Astellas Pharma has announced. The findings presented at the American Academy of Ophthalmology (AAO) 2023 Annual Meeting, revealed that the treatment continued to reduce the rate of geographic atrophy lesion growth for both every month and every-other-mo

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Bayer doubles down on Factor XIa with new phase 3 trial

pharmaphorum

Bayer doubles down on Factor XIa with new phase 3 trial Phil.

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MHRA authorises new treatment for rare lung cancer

European Pharmaceutical Review

A new medicine to treat adults with non-small cell lung cancer (NSCLC) with a rare mutation called KRAS G12C has been authorised by the UK Medicines and Healthcare products Regulatory Agency (MHRA). According to the MHRA, Mirati Therapeutics B.V.’s Krazati ® (adagrasib) can be used in this indication in individuals who have an advanced form of the disease, or it has spread to other parts of the body.

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Cream dosed drug patent expirations by year

Drug Patent Watch

This chart shows the patent expirations for cream dosed drugs over the next decade. The term of drug patents varies. The basic term for a patent is 20 years from… The post Cream dosed drug patent expirations by year appeared first on DrugPatentWatch - Make Better Decisions.

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