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The Important Role that Biopharmaceutics Plays in Accelerating Early-Phase Drug Development

Pharmaceutical Technology

Biopharmaceutics is a scientific discipline that examines the interrelationship of the physicochemical properties of the drug, the dosage form in which the drug is given, and the route of administration on the rate and extent of systemic drug absorption ( Applied Biopharmaceutics and Pharmacokinetics, Shargel, Wu-Pong and Yu, 5th Edition ).

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The rising importance of containment in small molecule drug development

Pharmaceutical Technology

HPAPIs may now represent more than 30% of the drug development pipeline. Within that figure, GlobalData estimates that around 60% of pipeline HPAPIs are developed to target oncology. Nowadays, you have drugs against cancer which have a very high impact even at a very low dosage.”.

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Can the FDA keep the momentum going for rare disease drug approvals?

Pharmaceutical Technology

Nicklas Westerholm, the CEO and president of orphan drug developer Egetis Therapeutics, says disease awareness amongst paediatric neurologists and endocrinologists is low for MCT8 deficiency. The FDA will weigh the concerns and benefits of this drug before its PDUFA date in October.

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Six things to look for when choosing an R&D tablet press

Pharmaceutical Technology

For Skyepharma, a CDMO specialising in oral solid dosage forms, notable reductions in costly product waste was one advantage. Versatility Finding a versatile R&D tablet press is key for flexible drug development. Testing a formulation on MEDELPHARM’s single-punch tablet press required just 0.9kg of powder.