STAT

JUNE 24, 2024

In the Phase 2 trial, the results of which were detailed in Nature Medicine , patients who took extended release ketamine tablets at an 180mg dosage twice weekly showed a “statistically significant and clinically meaningful improvement in depressive symptoms” compared to a placebo. Other dosages saw less of an impact.

Dosage 213

Dosage 213

PharmaTech

DECEMBER 6, 2024

In this exclusive Drug Digest video interview an industry expert discusses key trends impacting solid dosage drug development and manufacturing.

Dosage 64

Dosage Drug Development 64

STAT

MAY 28, 2024

The trial, called the ASPEN study, tested two dosages of the drug, and the company said both significantly cut rates of pulmonary exacerbations.     The drug, brensocatib, reduced so-called pulmonary exacerbations by roughly 20% versus placebo in patients with bronchiectasis, hitting the trial’s primary endpoint.

Dosage 244

Dosage 244

STAT

APRIL 21, 2023

and Susan Collins (R-Maine) would cap insured patients’ insulin costs at $35 per month for at least one insulin of each type and dosage form, and require pharmacy benefit managers to pass through rebates they collect from insulin manufacturers to the insurance plans that employ them. Jeanne Shaheen (D-N.H.) Read the rest…

Dosage 245

Dosage Packaging Diabetes 245

STAT

OCTOBER 27, 2022

Over the past week, Areva Pharmaceuticals began marketing vials of fludarabine at a wholesale price of $2,736, a much steeper cost than the $272 charged for the same dosage by Fresenius Kabi and the $109 price tag from Teva Pharmaceuticals, according to data from IBM Micromedex, which gathers pricing data that is reported by manufacturers.

Dosage 243

Dosage Drug Pricing 243

STAT

JULY 2, 2024

Last year Moderna conducted a Phase 1/2 clinical trial of its candidate mRNA-1018, testing H5 and H7 versions at several dosages in a regimen of two shots separated by three weeks. ” The company has already been working on mRNA-based pandemic vaccines, specifically targeting H5 and H7 avian influenza viruses.

Vaccines 306

Vaccines Dosage 306

PharmaTech

OCTOBER 30, 2024

In this podcast episode, we discuss trends in dosage forms, specifically oral solid dosage, as viewed by five industry experts who recently exhibited at CPHI Milan.

Dosage 52

Dosage 52

Welltopia Pharmacy

DECEMBER 11, 2023

What is L-Theanine? L-Theanine is a non-protein amino acid and it’s the main component of Green/Black tea, providing tea’s unique

Dosage 98

Dosage 98

Pharmaceutical Technology

AUGUST 21, 2023

The EC approved Janssen's Type II variation application for reduced dosing frequency of bispecific antibody TECVAYLI for multiple myeloma.

Dosage 98

Dosage 98

STAT

AUGUST 11, 2023

Specifically, 99% of hospitals pharmacists reported shortages, which is causing 85% to ration treatments and 84% to rely on different dosages.

Hospitals 229

Hospitals Compounding Pharmacies Dosage Chemotherapy 229

PharmaTech

OCTOBER 7, 2024

Pharmaceutical Technology Europe sat down with Uwe Hanenberg, Head of Product Implementation at Recipharm, to talk about key trends shaping the oral solid dosage market, including technology advances and industry investments.

Dosage 52

Dosage 52

PharmaTech

JANUARY 31, 2024

This article introduces that the basic technique for tolerance interval is implemented using the conventional range 85–115% LC where the proposed range in the PF is not taken into account.

Dosage 98

Dosage 98

Express Pharma

SEPTEMBER 3, 2023

Biocon recently announced that its step-down, wholly-owned subsidiary, Biocon Generics has acquired Eywa Pharma’s oral solid dosage manufacturing facility, located in Cranbury, New Jersey, US, effective September 1, 2023. A company statement informed, “The facility is acquired for a total consideration of $7.7

Dosage 107

Dosage 107

PharmaTech

DECEMBER 19, 2024

A case study in converting a solution formulation of a protein into an oral solid dosage form utilizing a fluid bed granulation process and some of the complexities involved.

Dosage 40

Dosage 40

STAT

MAY 15, 2024

At the time, the Food and Drug Administration required Amgen to run a trial confirming earlier test results, as well as a so-called post-marketing study to examine safety and effectiveness at different dosages, in order to gain full approval. Continue to STAT+ to read the full story…

Dosage 215

Dosage 215

STAT

OCTOBER 28, 2022

 Over the past week, Areva Pharmaceuticals began marketing vials of fludarabine at a wholesale price of $2,736, much more than the $272 charged for the same dosage by Fresenius Kabi and the $109 price from Teva Pharmaceuticals.

Drug Pricing 203

Drug Pricing Dosage Chemotherapy Hospitals 203

European Pharmaceutical Review

MARCH 22, 2023

The technology is an additive manufacturing process which enables the development and production of complex formulations and geometrical structures of oral dosage forms to optimise the release profiles of common pharmaceuticals in addition to new drug developments.

Dosage 105

Dosage Drug Development 105

European Pharmaceutical Review

AUGUST 25, 2022

The investigation was launched after NDMA and NDEA were detected in a finished dosage form, though neither were identified in the bulk drug product. With blister packaging among the most commonly used packaging type for pharmaceutical products worldwide, the findings could have significant implications for industry.

Packaging 143

Packaging Dosage 143

Pharmacy Joe

OCTOBER 25, 2023

Subscribe on iTunes , Android , or Stitcher If you navigate to the page on the website for the Institute for Safe Medication Practices that once hosted the document titled “Oral Dosage Forms That Should Not Be Crushed” you will instead find a notice that the list has been removed from the ISMP website.

Dosage 111

Dosage Inpatient Packaging Documentation 111

Express Pharma

MARCH 3, 2024

DKSH’s Business Unit Performance Materials will provide business development, marketing, sales, logistics, and distribution services for Lactalis’ pharma grade lactose for customers producing Finished Dosage Forms (FDFs), including tablets, pills, capsules, liquid solutions, among others in these key markets.

Dosage 94

Dosage 94

LifeProNow

MAY 17, 2023

The recommended starting dosage for the treatment of agitation associated with dementia due to Alzheimer’s disease is 0.5 Patients should increase the dosage on days 8 through 14 to 1 mg once daily, and on day 15 to 2 mg once daily. mg taken once daily on days 1 to 7. The recommended target dose is 2 mg once daily.

Dosage 130

Dosage Nursing Homes Assisted Living Pharmaceutical Companies 130

STAT

MAY 29, 2024

Nearly one-third halted treatment within four weeks, before recommended dosages reached the targeted strength. The insurer analyzed pharmacy and medical claims of nearly 170,000 people between July 2014 and December 2023 and found 58% did not complete a 12-week course of the medicines.

Diabetes 189

Diabetes Dosage 189

PharmaTech

SEPTEMBER 2, 2023

Coprocessed excipients save time and cost while improving performance in a widening array of dosage forms.

Dosage 96

Dosage 96

STAT

DECEMBER 19, 2022

The additions come as Lilly last week flagged challenges to meet demand for the two drugs, especially as it makes six dosage forms of Mounjaro and four of Trulicity. The Trulicity, another diabetes treatment in the company’s stable and its biggest-selling drug, was also added to the FDA shortage list.

Diabetes 168

Diabetes Dosage 168

Drug Patent Watch

DECEMBER 5, 2023

For a different perspective, see the most popular dosage types. This chart shows the pharmaceutical companies with the most implant dosed drugs. The companies with the most implant dosed drugs… The post Which pharmaceutical companies have the most implant dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceutical Companies 105

Pharmaceutical Companies Pharmaceutical Companies Dosage 105

European Pharmaceutical Review

NOVEMBER 22, 2022

Radio-imaging agents embedded in specific components of the dosage form were added in early development of the formulation to assess and confirm the location of drug release in the GI tract. According to Triastek, the radio-imaging agents help protect the tablets from dissolving in the stomach.

Dosage 111

Dosage 111

FDA Law Blog: Biosimilars

JUNE 13, 2024

While the relevant regulation defines “drug product” as the “finished dosage form,” which theoretically includes the delivery device, the Court again falls back on the wording in 21 C.F.R. The Court addressed Teva’s valid argument that the Inhaler Patents are drug product patents and thus listable.

Dosage 116

Dosage 116

PharmaTech

SEPTEMBER 20, 2024

The announcement of the pairing comes several months after Adare Pharma Solutions said it would upgrade several of its facilities, including in Milan, Italy, where the 3D printing operations will be located.

Dosage 52

Dosage 52

Drug Patent Watch

NOVEMBER 14, 2022

For a different perspective, see the most popular dosage types. This chart shows the pharmaceutical companies with the most suppository dosed drugs. The companies with the most suppository dosed drugs…. The post Which pharmaceutical companies have the most suppository dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceutical Companies 98

Pharmaceutical Companies Pharmaceutical Companies Dosage 98

Drug Patent Watch

APRIL 28, 2023

For a different perspective, see the most popular dosage types. This chart shows the pharmaceutical companies with the most spray dosed drugs. The companies with the most spray dosed drugs… The post Which pharmaceutical companies have the most spray dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceutical Companies 94

Pharmaceutical Companies Pharmaceutical Companies Dosage 94

Drug Patent Watch

APRIL 22, 2023

For a different perspective, see the most popular dosage types. This chart shows the pharmaceutical companies with the most syrup dosed drugs. The companies with the most syrup dosed drugs… The post Which pharmaceutical companies have the most syrup dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceutical Companies 93

Pharmaceutical Companies Pharmaceutical Companies Dosage 93

STAT

OCTOBER 5, 2023

PTO’s Patent Trial and Appeal Board said that Mylan had shown a reasonable likelihood that the Novo patent covering dosage regimes for the drugs was invalid.  The U.S.

Dosage 179

Dosage Packaging Diabetes Hospitals 179

PharmExec

OCTOBER 7, 2024

Approval was based on results from Phase I clinical safety studies, which demonstrated that using three tubes of Ameluz maintained similar safety and systemic exposure levels as one tube in treating actinic keratosis in patients undergoing photodynamic therapy.

Dosage 52

Dosage 52

Outsourcing Pharma

APRIL 11, 2024

It concentrates on small molecule dosage forms including sterile and non-sterile liquids, solids, and semi-solids products. Adragos Pharma is a contract development and manufacturing organization (CDMO) that provides development and manufacturing services for drug products.

Dosage 80

Dosage 80

Med Ed 101

JANUARY 1, 2023

We’ve outlined some of the most important pharmacokinetic, pharmacogenomic, and dosage form clinical pearls in the table below. Opioids are commonly used in clinical practice. Selection on these agents can often be confusion.

Dosage 98

Dosage 98

Express Pharma

JANUARY 2, 2024

The company informed that the formulation offers lesser side effects in comparison to existing oral dosage forms of Enzalutamide. Unlike fixed-dose tablets, doctors can adjust the dosage to fit each patient better. BDR Pharmaceuticals has introduced BDENZA, an oral solution in 32mg/mL for the management of prostate cancer.

Dosage 90

Dosage 90

STAT

MAY 23, 2023

The study results also suggest the Pfizer medicine may be as effective for weight loss as Ozempic, although there are stark differences in dosage levels. Meanwhile, an oral drug from Pfizer causes a similar amount of weight loss as Ozempic, according to results from a Phase 2 clinical trial, CNBC says. Walgreens asked a U.S.

Drug Pricing 175

Drug Pricing Dosage Diabetes 175