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Drug development trends: insight from Thermo Fisher’s Anil Kane

European Pharmaceutical Review

Dr Kane leads a team of subject matter experts at Thermo Fisher, covering drug products in both sterile injectable dosage and oral solid dosage forms. Small molecules continue to be of interest going into oral solid dosage forms” AK: That’s a very interesting question that can be addressed in a few different ways.

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Over-the-Counter Choices Pharmacist Role and Resources

FADIC

OTC drugs come in various forms, including tablets, capsules, creams, and liquids, and are generally labeled with clear instructions on proper usage and dosage. Its OTC drug section covers a broad range of OTC medications, offering detailed descriptions, recommended dosages, and potential drug interactions.

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Eli Lilly Files Suit Challenging the FDA’s Drug Classification of Retatrutide

Big Molecule Watch

Retatrutide is an investigational product which, according to Lilly, may have potential as an obesity treatment as well as a treatment for type-2 diabetes and other chronic conditions. The FDA determined that, under its regulatory definition, only alpha amino acids are counted towards the “greater than 40 amino acids” threshold.

Dosage 49
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Hypertension

RX Note

Definition Hypertension is most commonly defined as persistent elevation of systolic BP of 140 mm Hg or greater and/or diastolic BP of 90 mm Hg or greater. However, definition vary by professional organization.

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Dry Eye

RX Note

Historically, dry eye disease (DED) has been classified into 2 general groups: Aqueous deficient DED Decreased tear production due to Sjogren's syndrome, older age and diabetes mellitus. Medical conditions Patients with rheumatoid arthritis , diabetes or thyroid problems are more likely to experience dry eyes.

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Chronic Kidney Disease

RX Note

Definition CKD is defined by the presence of kidney damage or decreased kidney function for 3 or more months , irrespective of the cause. Treating the underlying cause , such as diabetic kidney disease, viral infections, cardiac or hepatic disorders, administration of nephrotoxic drugs. However, a low protein diet [0.55-0.6

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Pain

RX Note

diabetic neuropathy, phantom limb) or central (spinal cord injury, post stroke) or both (postherpetic neuralgia). Strong opioids, of which morphine is considered the gold standard, have no ceiling effect, and therefore increased dosage continues to give increased analgesia, but side effects often limit the effectiveness.