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Trials leave Galapagos’ SIK programme looking under the weather

pharmaphorum

Galapagos has had to send its SIK inhibitor programme back to the drawing board after its lead compound GLPG3970 has failed two of three clinical trials, adding to a string of disappointments for the Belgian biotech. . The preclinical compounds are expected to move into the human testing stage next year.

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Innovation in chemotherapy: Leading companies in platinum-based cancer drug compositions

Pharmaceutical Technology

These compounds cause their therapeutic effect by inhibiting DNA synthesis. The company has filed several patents involving platinum compounds and developed drugs such as cisplatin and carboplatin. Several platinum-based drugs such as cisplatin, carboplatin and oxaliplatin are widely used in cancer therapy.

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Online Medical Resources

RX Note

IWK Compounding Formulas USP-NF WHO Pharmacopoeia Pregnancy Australia TGA Best Use of Medicines in Pregnancy Pregnancy and Breastfeeding Medicines Guide

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Intelligent Automation in Pharmaceutical Industry (AI & ML)

PharmaShots

Major companies use this approach to find the right compound and check its effects on patients based on biological factors. Automation has deeply influenced the way we earlier saw multifactorial disorders.

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Approach to Fibrocystic Breasts with Hashimoto’s

The Thyroid Pharmacist

Interestingly, these foods can also contain estrogen-mimicking compounds, which can contribute to estrogen dominance. A 2018 study found that a compound called zearalenone, an estrogen-like fungi, can colonize wheat, corn, and other grains. Mayo Clinic. J Endocrinol Invest. 2015;38(9):971-975. Fibrocystic breasts.

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Got Acid Reflux? And Hashimoto’s?

The Thyroid Pharmacist

9] When the body is exposed to an allergen, histamine production increases and turns on inflammatory processes to protect the body from that compound. Cleveland Clinic. Mayo Clinic. Cleveland Clinic. Minerva Med. 2017;108(6):496-501. doi:10.23736/S0026-4806.17.05379-4 [5] Hypochloridia. Reviewed on June 27, 2022.

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How Aloe Vera Supports Thyroid Health

The Thyroid Pharmacist

Other plants also contain this organic compound, but aloe vera contains an especially large amount, with over 12 different anthraquinones. The active compounds found in aloe vera have been found to have immune-modulating benefits. Utilization of Aloe Compounds in Combatting Viral Diseases. Immune Health. Precautions.