World Pharma News

MARCH 8, 2024

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

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pharmaphorum

NOVEMBER 12, 2020

The company was founded as a spin-off of the University of Bern and Swiss research institute NCCR TransCure in April 2019, and is focused on the development of a new class of drugs that work on endocannabinoids, a type of neurotransmitter that bind to the receptors in the brain targeted by cannabinoid compounds.

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STAT

OCTOBER 25, 2024

By law, that should have prohibited compounding pharmacies from making copies of the drug, as they are allowed to do so only when the treatment is on the shortage list. The agency then made a sudden about-face, saying it would reconsider its decision and allow compounders to continue for the meantime.

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Safe Biologics

JUNE 12, 2023

Op-ed: IRA Drug Price Controls Will Hurt Cancer Drug Development On May 18th, an op-ed by ASBM Steering Committee Member Andrew Spiegel ran in the Reading Eagle. Under the IRA, Medicare will be able to negotiate with drug makers for lower prices on an expanding list of brand-name medications.

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Safe Biologics

JUNE 12, 2023

Op-ed: IRA Drug Price Controls Will Hurt Cancer Drug Development On May 18th, an op-ed by ASBM Steering Committee Member Andrew Spiegel ran in the Reading Eagle. Under the IRA, Medicare will be able to negotiate with drug makers for lower prices on an expanding list of brand-name medications.

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Drug Patent Watch

DECEMBER 10, 2024

This shift has led to the emergence of integrated contract development and manufacturing organizations (CDMOs), which provide end-to-end support for drug developers. billion in 2022 and is expected to grow at a compound annual growth rate of 5.3% Reshaping drug development through CRO/CDMO integration.

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STAT

JUNE 20, 2024

We have adjusted our settings to accept postcards and telegrams… After taking legal action last year, Eli Lilly filed even more lawsuits against several spas, compounders and wellness centers over unapproved versions of tirzepatide, which is the active ingredient in Mounjaro and Zepbound,   STAT notes.

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Pharmaceutical Technology

DECEMBER 16, 2022

In November, Sanofi and the Drugs for Neglected Diseases Initiative (DNDi) reported positive Phase II/III data for a compound that both organizations codeveloped as a potential treatment for sleeping sickness, called acoziborole. The company now expects to complete its submission for a BLA with the FDA by the end of the year.

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Pharmaceutical Technology

SEPTEMBER 3, 2024

Syntekabio has entered a partnership with Enamine for supply, synthesis of compounds and synthetic drug development.

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European Pharmaceutical Review

OCTOBER 9, 2022

Research published in the journal Nature Chemistry , shows how researchers from Stanford University in the US uncovered a promising new method to synthetically manufacture the compound tigilanol tiglate, named EBC-46, which could offer targeted medicine for cancer and other diseases.

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Drug Patent Watch

DECEMBER 9, 2024

Scientists in this field analyze the chemical compounds in plants, animals, and microorganisms to discover potential new drugs. “Pharmacognosy is the bridge between traditional medicine and modern pharmaceutical science, offering a treasure trove of potential new drugs waiting to be discovered.”

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Pharmaceutical Technology

APRIL 30, 2024

Discover Ligand Pharmaceuticals Inc's groundbreaking patent for compounds treating leukemia and hematopoietic disorders. Explore the versatile pharmaceutical compositions and potential applications for innovative drug development.

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PharmaTech

OCTOBER 10, 2023

Developing and manufacturing complex novel oral solid dose products of highly potent compounds requires specialized expertise. Learn more about creating a safe, efficient and scalable drug development program with HPAPIs in this eBook.

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Pharmaceutical Business Review

FEBRUARY 7, 2024

Camino Pharma CEO and co-founder Gonul Velicelebi said: “Our Phase I study results showed that SBP-9330 has a favourable safety and tolerability profile and well-behaved pharmacokinetics in humans, supporting further clinical development and evaluation of the compound in a proof-of-concept study in smokers as an aid to smoking cessation. “We

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Pharmaceutical Business Review

MARCH 7, 2024

Additionally, Sionna is progressing with the development of compounds targeting complementary mechanisms. This capital raise provides financial flexibility positioning us to execute our clinical development plan with funding through 2026 and multiple value-creating clinical readouts.”

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Pharmaceutical Technology

JUNE 15, 2023

AI for drug development is rapidly streamlining R&D processes, speeding up time to market and providing a better experience for patients and providers. Learn more about the role of AI in drug development and how healthcare researchers are using it to shake up the field.

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European Pharmaceutical Review

OCTOBER 31, 2022

Solving this before the clinical stage ensures the viability of compounds…” Addressing bioavailability challenges in the first phases of development is essential to help create the most robust product profile and increase the potential for success as small molecule drugs move to the clinic.

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pharmaphorum

MAY 4, 2022

Testing drug compounds on a chip designed to mimic human organs sounds closer to science fiction than reality, yet the technology already exists and is already being put to use. The limits of animal models in drug discovery are well known.

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Pharmaceutical Technology

NOVEMBER 3, 2022

The funding will be used for the Phase III clinical trial and potential marketing of the investigational compound, ecopipam, for treating Tourette syndrome patients. The Food and Drug Administration granted Orphan Drug and Fast Track designation for ecopipam to treat Tourette syndrome.

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Pharmaceutical Technology

JUNE 15, 2023

Drug development is already a difficult endeavor, with the vast majority of R&D efforts failing to produce a market-worthy product. Even reaching the clinical trial phase offers no guarantees, as only 12% of such drugs receive U.S. While this process is essential, it’s also slow, expensive and unpredictable.

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pharmaphorum

JUNE 30, 2022

Digital technologies are already helping to enable target identification, lead discovery, preclinical development, and clinical development, said Merck. The hope is that by using AI and ML capabilities, the currently unpredictable process of drug development can become much more predictable, and as a result less expensive.

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PharmaTech

DECEMBER 17, 2024

Lucy Zhou, Skin Lab Manager, discusses the importance and applications for utilizing IVPT during formulation development of novel topical compounds to help select excipients and permeation enhancers that will properly deliver the drug into the desired layer of the skin or system.

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Pharmaceutical Technology

OCTOBER 20, 2022

According to preclinical research, PIC compounds modulate protein translation but do not hinder the process. The post PIC raises funds through Series A for breast cancer drug development appeared first on Pharmaceutical Technology.

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Syner-G

SEPTEMBER 15, 2023

This shift from a linear to a network approach enhances the potential for one drug to target multiple sites. Structure-based drug design has evolved, facilitating the exploration of novel chemical probes and lead compound potency, and molecular docking utilizes target structures to predict interactions and offers simplicity and speed.

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PharmaTech

MARCH 21, 2023

Thousands of drug candidates are abandoned annually due to solubility and bioavailability issues, but advanced formulation technologies can profoundly impact how a drug compound is processed in the body and improve the fate of many of these candidates, improving pharmacokinetic profiles and pharmacodynamic responses.

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World Pharma News

AUGUST 9, 2024

The natural world is rich in chemical compounds with remarkable medicinal properties. This discovery revolutionized the treatment of bacterial infections and highlighted the potential of natural compounds in medicine. A notable example is penicillin, discovered by chance from the Penicillium mold.

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pharmaphorum

NOVEMBER 9, 2022

Sanofi has tapped into the artificial intelligence expertise of Chinese biotech Insilico Medicine with a six-compound drug discovery collaboration that could be worth up to $1.2 Insilico’s in-house drug development efforts are led by a drug against an as-yet undisclosed target in phase 1 clinical testing.

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European Pharmaceutical Review

FEBRUARY 27, 2023

Due to more biopharmaceutics classification system (BCS) II and BCS IV molecules being evaluated in early development, a market report has signalled that the bioavailability enhancement market will grow at a steady rate between 2022 to 2035.

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European Pharmaceutical Review

JULY 24, 2023

A paper published in Pharmaceutics has proposed how a personalised preparation quality assurance programme can achieve this when these products are developed in compounding laboratories. PACMI selects a drug on a quarterly basis. It requests that compounding laboratories adhering to the programme send samples of it.

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pharmaphorum

MARCH 24, 2022

GlaxoSmithKline has thrown its financial and drug development weight behind LifeMine Therapeutics, a US startup that aims to find new therapeutics from fungi – widely regarded as an underexplored resource of biologically-active compounds.

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European Pharmaceutical Review

JUNE 28, 2023

million by 2030, growing at a compound annual growth rate (CAGR) of 5.57 Growth of the pharmaceutical and biotechnology industries, plus the need for accurate and precise analytical tools in drug development and quality control are influencing factors. percent from 2023 to 2030. What is driving the HPLC market?

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pharmaphorum

JULY 21, 2021

The winning team relied on “handcrafted” features that incorporated their own insights into drug development timelines and which data entries should be discarded, according to MIT. The results were interesting, but the team wanted to do better. .

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European Pharmaceutical Review

JULY 25, 2023

A compound annual growth rate (CAGR) growth of 5.9 Complex compounds offer targeted, effective medicines and typically outperform small molecule APIs. Disease areas Development of APIs for niche sectors such as rare or uncommon diseases offers new markets and can give small molecule API companies “an edge”, stated the report.

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European Pharmaceutical Review

NOVEMBER 6, 2023

million in 2023, with a predicted compound annual growth rate (CAGR) of 4.1 Demand for cell lines “in drug development , vaccine production, and therapeutic research is surging”, setting the market up for significant expansion, Ghosh noted. Total cell line product sales are expected to reach $3,124.4

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European Pharmaceutical Review

DECEMBER 16, 2022

According to a report by Future Market Insights (FMI), the global Alzheimer’s therapeutics market is expected to grow at a compound annual growth rate (CAGR) of 9.3 FMI stated drug manufacturers have been unable to validate the significant clinical benefits of treatment for numerous new compounds due to strict regulations.

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Express Pharma

JUNE 11, 2024

With the evolving landscape of drug development and innovations, several institutes are serving as catalysts by partnering with pharmaceutical companies to drive progress at various stages of research and development.

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European Pharmaceutical Review

MARCH 2, 2023

A Gastrointestinal Simulator (GIS) was found to be superior to the traditional United States Pharmacopoeia (USP) method in predicting in vivo performance of Biopharmaceutics Classification System (BCS) Class IIa compounds. Katona et al.

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