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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

People over 65 make up only 14% of the population but account for 56% of hospitalizations for adverse drug events (ADEs) (Agency for Healthcare Research and Quality, AHRQ, 2021). The side effects can compound, resulting in a greater negative impact on a patient’s health than the individual effects of one medication alone.

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Low Dose Naltrexone and Hashimoto’s

The Thyroid Pharmacist

Many times, people have been able to eliminate their symptoms and reduce their dosages of medications. LDN can be taken in the form of a compounded tablet, capsule, liquid, or transdermal formulation. It’s also best to work with a compounding pharmacy that can help you titrate your dose correctly.

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How can the pharma industry navigate issues in the global supply chain to minimise drug shortages?

pharmaphorum

While navigating changes has long been a challenge for the industry, the last two years’ events have made supply chain management significantly more difficult. Supply chain challenges are compounded by the broader global picture, such as the war in Ukraine, the great resignation, and natural disasters.

Diabetes 111
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Top Performing Drug of 2021 - Trulicity (February Edition)

PharmaShots

Active Ingredient: dulaglutide Dosage Forms & Strengths: Injection: 0.75 Active Ingredient: dulaglutide Dosage Forms & Strengths: Injection: 0.75 To reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus who have established cardiovascular disease or multiple cardiovascular risk factors.

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Novo Nordisk blockbuster Ozempic boasts 23% sales surge in 2023

Pharmaceutical Technology

Originally granted approval in its largest market, the US, in 2017, Ozempic has subsequently obtained approval for three distinct dosages, 0.5mg, 1.0mg, and 2.0mg, for the treatment of type 2 diabetes. This represents a significant 83% increase in sales between 2022–2029, demonstrating a compound annual growth rate (CAGR) of 9%.

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How using AI in clinical trials accelerates drug development

Pharmaceutical Technology

Once the target is identified, researchers work to develop a compound that can interact with it. After a promising compound has been identified, it’s tested in preclinical models to evaluate its safety and efficacy. The target could be an enzyme or receptor in the human body, or it could be an organism that causes disease.

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Enforcement Trends: CDER Presentation Confirms Fewer Warning Letters Are Issued by FDA for OAI Inspections

FDA Law Blog: Biosimilars

These figures confirm that, although the vast percentage of active ingredients of important pharmaceuticals comes from overseas, the actual manufacturing of finished dosage form drugs occurs in the United States or Europe (broadly defined to include the UK).

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