ISMP Safety Brief: Prevent Additional Patient Harm and Deaths From Accidental Daily Methotrexate Dosing
National Association of Boards of Pharmacy
MARCH 22, 2024
The labeled indications for methotrexate later expanded to include the treatment of non-oncologic conditions, including psoriasis and rheumatoid arthritis. The community pharmacy dispensed a three-month quantity of medication but provided instructions on the label to take 15 mg (six 2.5 mg tablets) once daily.
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