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These molecules are proven to be effective at much smaller dosage levels than traditional APIs. Some examples of HPAPIs are cytotoxic compounds and hormones such as oestrogen. A new compound of unknown potency and toxicity. All dosage forms may utilise HPAPIs including parenteral and solid dosage forms.
Deferoxamine binds with ferric iron (Fe3+) to form ferrioxamine, a water-soluble compound excreted in the urine. As 1,2] Severe symptoms such as hypovolemia, shock, metabolic acidosis Persistent and severe GI symptoms Lethargy or toxic appearance Serum iron level greater than 500 mcg/dL What is the dosage of deferoxamine for iron toxicity?
The side effects can compound, resulting in a greater negative impact on a patient’s health than the individual effects of one medication alone. Healthcare providers review medication lists, adjust dosages, and coordinate care among multiple specialists. British Journal of ClinicalPharmacology, 67(6), 689–700.
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