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ACMT Toxicology Visual Pearl: The Bark with Some Bite

ALiEM - Pharm Pearls

The active compound, salicin, is metabolized to salicylic acid in the body providing analgesic and antipyretic effects [2]. European Journal of Clinical Pharmacology. European Journal of Clinical Pharmacology. Willow tree bark contains salicin from which aspirin (acetylsalicylic acid) can be derived.

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The challenge of handling highly potent API and ADCs in analytical chemistry

European Pharmaceutical Review

Some examples of HPAPIs are cytotoxic compounds and hormones such as oestrogen. A new compound of unknown potency and toxicity. Over 25 percent of total drugs worldwide are classified as containing HP compounds and 30 percent of product candidates in the development pipeline are also HPAPIs, showing that this trend will continue.

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New radiopharmaceutical laboratory opens in Germany

European Pharmaceutical Review

Additionally, the new laboratory offers Ariceum the ability to carry out on-site process, method, validation and formulation development as well as preliminary stability analysis of its radiolabeled compounds.

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ACMT Toxicology Visual Pearl: Who Doesn’t Like a Nice Rosé?

ALiEM - Pharm Pearls

 Deferoxamine binds with ferric iron (Fe3+) to form ferrioxamine, a water-soluble compound excreted in the urine. As Hypersensitivity reactions to rifampin: Pathogenetic mechanisms, clinical manifestations, management strategies, and review of the anaphylactic-like reactions. Medicine (Baltimore) 1999;78(6):361-9.

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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

The side effects can compound, resulting in a greater negative impact on a patient’s health than the individual effects of one medication alone. British Journal of Clinical Pharmacology, 67(6), 689–700. Retrieved from British Journal of Clinical Pharmacology Jyrkka, J., A., & O’Mahony, M. Korhonen, M.

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Online Medical Resources

RX Note

IWK Compounding Formulas USP-NF WHO Pharmacopoeia Pregnancy Australia TGA Best Use of Medicines in Pregnancy Pregnancy and Breastfeeding Medicines Guide

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Recommended Medical Reference

RX Note

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)