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Opinion: STAT+: Biotech investors: Stop expecting CRISPR science to make big leaps

STAT

An increasing challenge in the treatment of oral cancer is that tumors become resistant to chemotherapy. These studies often do not make a splash in the field and are almost never presented at major meetings, yet they provide guidance as to how best to harness the power of this technology.

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STAT+: Jazz Pharmaceuticals to acquire Chimerix and its experimental brain cancer drug

STAT

It responds poorly to chemotherapy and is usually driven by a mutation that can’t be drugged with traditional approaches. But in a clinical trial presented last year , 14 out of 50 patients with relapsed disease saw their tumors shrink. Median survival is generally cited as less than a year. 

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Roche presents five-year survival outcomes for Tecentriq plus chemotherapy in ES-SCLC

Express Pharma

Results presented from the Phase III IMpower133 study and extension trial IMbrella A, show Roche’s Tecentriq (atezolizumab), in combination with chemotherapy, demonstrates a potential long-term overall survival (OS) benefit as first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). Presented at WCLC 2023.

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STAT+: Data on AstraZeneca cancer drug allay safety concerns but treatment still faces questions

STAT

On Monday, data presented here from a trial of the drug in advanced non-small cell lung cancer provided at least a fuller look. Patients were randomized to either receive chemotherapy or Dato-DXd, which AstraZeneca is developing with Daiichi Sankyo. Continue to STAT+ to read the full story…

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STAT+: Results on Novartis prostate cancer therapy could expand its use

STAT

MADRID — Results presented Monday could expand the use of a Novartis therapy for metastatic prostate cancer, moving it from a treatment used after chemotherapy to one with demonstrated benefits beforehand as well.

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STAT+: Targeted drug greatly slows progression of a brain cancer

STAT

CHICAGO – An experimental drug dramatically slowed the growth of glioma, a type of brain cancer, if the tumor carried a specific type of genetic alteration, researchers said Sunday, potentially sparing patients exposure to radiation and chemotherapy.

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STAT+: There’s a bill well-suited for drug shortage reforms, but Congress isn’t interested

STAT

WASHINGTON — Congress is considering a must-pass pandemic preparedness bill that presents a good opportunity to fix the nation’s current drug shortages problem, which both parties want to do. But most indications are that lawmakers will let that opportunity pass them by.