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Japan grants approvals for Merck’s Keytruda to treat different cancers

Pharmaceutical Technology

The approvals include Keytruda plus chemotherapy as neoadjuvant treatment and then continued as a single agent for adjuvant treatment post-surgery in hormone receptor-negative and human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients. This approval is based on KEYNOTE-564 trial data.

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Keytruda approved as first-line advanced cervical cancer therapy

pharmaphorum

Keytruda (pembrolizumab) can be used in combination with chemotherapy, with or without bevacizumab, to treat patients with persistent, recurrent or metastatic cervical cancer where the tumour expresses a certain level of PD-L1. Some cancer cells contain large amounts of PD-L1, which helps them to evade the body’s immune system.