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STAT+: More hospital pharmacists are rationing drugs due to increasing shortages

STAT

And the problem has become so bad – especially for chemotherapies — that one-third of hospital pharmacists reported their institutions are rationing, delaying, or canceling treatments or procedures, according to a new survey.

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FDA drug dosage optimisation guidelines signal clinical trial reform

Pharmaceutical Technology

In January, amidst calls to improve patient safety by optimizing licensed drug formulations, the FDA released a draft guidance that signalled a departure from the most commonly used method of identifying a new therapy’s ideal dosage. The focus on identifying the ideal drug dosage is not new. What is drug dose optimisation?

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STAT+: Pharmalittle: Drugmaker raises price of old chemo med 10-fold amid shortages; Alnylam cites drug-price law in halting trial

STAT

 Over the past week, Areva Pharmaceuticals began marketing vials of fludarabine at a wholesale price of $2,736, much more than the $272 charged for the same dosage by Fresenius Kabi and the $109 price from Teva Pharmaceuticals.

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Drug Formulation In-Depth Focus 2022

European Pharmaceutical Review

Cyclodextrins are a frequently used excipient in the pharmaceutical industry, employed in multiple dosage forms and with multiple purposes simply because of their numerous positive properties, including being generally well tolerated and safe. Could the new wave of taxane chemotherapies succeed where traditional chemotherapies have failed?

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Alembic receives tentative approval from USFDA for Ivosidenib Tablets

Pharmaceutical Business Review

The medication is indicated for use in various patient groups, including those with newly diagnosed Acute Myeloid Leukemia (AML) who are over 75 years old or have other health conditions that prevent them from undergoing intensive chemotherapy. The market size for these tablets is estimated at $275m for the same 12-month period.

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FDA grants orphan drug designation for Syros’ pancreatic cancer treatment

Pharmaceutical Technology

An oral inhibitor of cyclin-dependent kinase 7 (CDK7), SY-5609 is presently being analysed alongside chemotherapy as a treatment for relapsed metastatic pancreatic cancer patients. Tolerability and safety, as well as efficacy parameters, such as disease control rate and progression-free survival, will be analysed in the trial. .

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Are Exact Strength Medications Exact? Why Standard Strength is Better for Veterinary Patients

epicur

This results in requests for precise dosages such as 1.22 However, the more closely we look at what it takes to compound an exact strength, the clearer it becomes standard dosages are more beneficial to both patients and veterinary practices. Epicur’s chemotherapy tablets are a great example of this. milligrams or other 0.1

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