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STAT+: More hospital pharmacists are rationing drugs due to increasing shortages

STAT

And the problem has become so bad – especially for chemotherapies — that one-third of hospital pharmacists reported their institutions are rationing, delaying, or canceling treatments or procedures, according to a new survey.

Hospitals 246
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STAT+: Pharmalittle: Drugmaker raises price of old chemo med 10-fold amid shortages; Alnylam cites drug-price law in halting trial

STAT

 Over the past week, Areva Pharmaceuticals began marketing vials of fludarabine at a wholesale price of $2,736, much more than the $272 charged for the same dosage by Fresenius Kabi and the $109 price from Teva Pharmaceuticals.

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Drug Formulation In-Depth Focus 2022

European Pharmaceutical Review

Cyclodextrins are a frequently used excipient in the pharmaceutical industry, employed in multiple dosage forms and with multiple purposes simply because of their numerous positive properties, including being generally well tolerated and safe. Could the new wave of taxane chemotherapies succeed where traditional chemotherapies have failed?

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Private health firm Sciensus fails to fix defects that led to UK patient’s death

The Guardian - Pharmaceutical Industry

Exclusive: Regulator extends part suspension of licence to July 2024 after IT blunder led to incorrect dosage of cancer treatment A private health company paid millions by the NHS has failed to fix safety defects that led to the death of a cancer patient, the Guardian can reveal.

Dosage 93
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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. Benefits of daily oral chemotherapy over IV.

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Alembic receives tentative approval from USFDA for Ivosidenib Tablets

Pharmaceutical Business Review

The medication is indicated for use in various patient groups, including those with newly diagnosed Acute Myeloid Leukemia (AML) who are over 75 years old or have other health conditions that prevent them from undergoing intensive chemotherapy. The market size for these tablets is estimated at $275m for the same 12-month period.

Dosage 59
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FDA grants orphan drug designation for Syros’ pancreatic cancer treatment

Pharmaceutical Technology

An oral inhibitor of cyclin-dependent kinase 7 (CDK7), SY-5609 is presently being analysed alongside chemotherapy as a treatment for relapsed metastatic pancreatic cancer patients. Tolerability and safety, as well as efficacy parameters, such as disease control rate and progression-free survival, will be analysed in the trial. .