STAT

SEPTEMBER 13, 2024

BARCELONA, Spain — Adding a second immunotherapy from Bristol Myers Squibb to an existing checkpoint inhibitor and chemotherapy improved responses for certain patients with a type of lung cancer, steering the approach into a Phase 3 study. 

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Chemotherapy 265

STAT

SEPTEMBER 13, 2024

  But she avoided digging into one particular subject: what she might have to endure with chemotherapy and radiation. When Rachel Guberman found out she had brain cancer, she did so much reading and Googling about the disease that she joked she had reached the end of the internet.  Continue to STAT+ to read the full story…

Chemotherapy 363

Chemotherapy Drug Development 363

STAT

OCTOBER 22, 2024

Like the two sickle cell gene therapies approved last year, Editas’ old program, Reni-Cel, required extracting a patient’s blood cells, editing them at a large facility, and then reinfusing — an expensive and difficult-to-scale process that requires patients to undergo intensive chemotherapy. 

Chemotherapy 322

Chemotherapy 322

European Pharmaceutical Review

FEBRUARY 15, 2024

A clinical trial in malignant pleural mesothelioma (MPM) has demonstrated the first successful combination of chemotherapy with a drug targeting cancer’s metabolism developed for the asbestos-induced disease in two decades. The anti-cancer treatment combines the new drug ADI-PEG20 and traditional chemotherapy.

Chemotherapy 105

Chemotherapy 105

STAT

JUNE 4, 2023

CHICAGO — An antibody that delivers chemotherapy directly to tumor cells extended the lives of women with a form of advanced ovarian cancer in a large study, researchers reported Sunday. months compared to just under 13 months for participants treated with standard chemotherapy. It was granted conditional approval in the U.S.

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Chemotherapy 323

Pharmafile

MARCH 4, 2024

The drug has been approved in combination with chemotherapy (carboplatin-pemetrexed) for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 […] The post FDA approves J&J’s Rybrevant with chemotherapy for NSCLC treatment appeared (..)

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Chemotherapy 110

STAT

JANUARY 24, 2024

A year after an investigation revealed widespread use of a substandard cancer drug, the World Health Organization and national drug regulators around the world have come under fire for failing to protect children from the dangerous chemotherapy. The WHO plays a major role in protecting people worldwide from bad medicines.

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Chemotherapy 351

European Pharmaceutical Review

MAY 3, 2023

The blood-brain barrier (BBB) in glioblastoma patients was opened temporarily using a novel, skull-implantable ultrasound device to deliver chemotherapy to the brain in a first in-human trial. Two chemotherapy drugs , paclitaxel and carboplatin were injected intravenously during the four-minute procedure.

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Chemotherapy 119

STAT

SEPTEMBER 25, 2023

For months, oncologist Kristen Rice found herself scrambling for cisplatin and carboplatin, two key chemotherapies used for many different cancers including ovarian, bladder, and lung cancer. We went to put in our chemotherapy order, and our supplier said, ‘We don’t have any.’ “It came without warning.

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Pharmacy Technician Chemotherapy Hospitals 344

STAT

SEPTEMBER 18, 2024

Susan underwent two lumpectomies, a mastectomy, radiation, and chemotherapy. She embarked on a challenging path of treatment, including a recurrence with stage 2 cancer four years later.

Chemotherapy 319

Chemotherapy 319

STAT

SEPTEMBER 8, 2022

months for comparator chemotherapy. In the study, called TROPICS-02, Trodelvy showed a median overall survival of 14.4 months compared to 11.2 The survival benefit of 3.2 months was statistically significant and translated into a 21% reduction in the risk of death. Continue to STAT+ to read the full story…

Chemotherapy 358

Chemotherapy 358

STAT

JANUARY 8, 2024

Johnson & Johnson said Monday that it would purchase Ambrx Biopharma for nearly $2 billion, picking up a company specializing in targeted chemotherapy treatments — one of the hottest areas of cancer drug development.     The deal, disclosed as the biopharma field marked the first day of the annual J.P.

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Drug Development Chemotherapy 325

STAT

DECEMBER 7, 2022

The charges are actually eating into their financial well-being, particularly for people who have cancer and have to make frequent visits to the hospital for treatments like radiation and chemotherapy. Read the rest…

Hospitals 334

Hospitals Chemotherapy 334

Express Pharma

OCTOBER 15, 2023

Venus Remedies has received marketing approval from the Philippines, the second largest ASEAN market, for six key chemotherapy drugs. Meanwhile, the company’s oncology wing has also secured marketing approval from Myanmar for the chemotherapy drug oxaliplatin.

Chemotherapy 105

Chemotherapy 105

STAT

OCTOBER 23, 2023

While the results assuaged some of the safety fears that flared when initial information was released over the summer, they only heightened concerns about the drug’s ability to outperform standard chemotherapy — though they perhaps pointed to an opportunity for the drug in a subset of patients.

Chemotherapy 307

Chemotherapy Drug Development 307

STAT

MAY 23, 2023

Many will endure multiple CT and MRI studies and intensive medical care, including surgery, radiation, chemotherapy, or immunotherapy. In 2023, just under 2 million Americans will be diagnosed with cancer. Fortunately, advances in treatment and novel therapies have steadily improved survival following a cancer diagnosis.

Chemotherapy 354

Chemotherapy 354

STAT

MAY 3, 2023

Immunogen released data from a trial comparing the new drug, Elahere, to traditional chemotherapy in 453 ovarian cancer patients who had already progressed on at least one other therapy and had a particular protein marker on their tumor. months for patients on chemotherapy. Patients who received Elahere lived a median of 16.46

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Chemotherapy 271

Pharmaceutical Technology

JULY 5, 2024

Approval is based on positive data from the Phase III FLAURA2 trial where Tagrisso plus chemotherapy showed PFS of 24.4

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Chemotherapy 98

STAT

APRIL 10, 2024

These include oxytocin, which is used during childbirth; Rho(D) immune globulin, which helps some women during pregnancy; standard-of-care chemotherapy, pain and sedation medicines; and ADHD pills. Unresolved shortages have, in fact, been hovering above 300 for more than a year as numerous basic and life-saving medicines are in short supply.

Chemotherapy 357

Chemotherapy Immunization Immunity 357

STAT

NOVEMBER 12, 2024

  The medicine, datopotamab deruxtecan, or Dato-DXd, is a type of next-generation chemotherapy called an antibody-drug conjugate that AstraZeneca and other companies have been pouring investments into. But full trial data published in September showed Dato-DXd did not outperform standard chemotherapy on overall survival. 

Chemotherapy 277

Chemotherapy 277

STAT

FEBRUARY 14, 2024

The move comes amid growing anxiety over shortages of numerous medicines — from chemotherapies to antibiotics — in recent years. Three group purchasing organizations, or GPOs, buy drugs on behalf of most hospitals in the U.S.,

Nursing Homes 354

Nursing Homes Hospitals Chemotherapy Drug Pricing 354

STAT

SEPTEMBER 5, 2024

For three decades, adults have benefited from a revolution in oncology treatment, as immunotherapies and targeted drugs have joined or replaced older, blunter tools like chemotherapy and radiation.    Children have been less fortunate. 

Chemotherapy 322

Chemotherapy Drug Development 322

STAT

MARCH 1, 2024

I recently started a patient with metastatic triple-positive breast cancer patient on a targeted therapy regimen consisting of capecitabine and neratinib, both oral chemotherapy pills that are dosed on a 21-day cycle.

Specialty Pharmacies 310

Specialty Pharmacies Chemotherapy 310

Express Pharma

SEPTEMBER 10, 2023

Results presented from the Phase III IMpower133 study and extension trial IMbrella A, show Roche’s Tecentriq (atezolizumab), in combination with chemotherapy, demonstrates a potential long-term overall survival (OS) benefit as first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). 0.91; p=0.0069). JTO Clin Res Rep.

Chemotherapy 111

Chemotherapy 111

STAT

MARCH 24, 2024

The latest entry is that of Catherine, the Princess of Wales, also known as Kate Middleton, who revealed she has cancer and is undergoing chemotherapy. As with her many of her predecessors, the princess’s story will likely both reveal and conceal, but I suspect it will ultimately both move and enlighten the public.

Chemotherapy 339

Chemotherapy 339

STAT

OCTOBER 20, 2023

Pharmacists increasingly are being asked to make drugs in bulk for hospitals that are in short supply, and they’re even beginning to make chemotherapies. But some in the industry worry about the unintended consequences of overreliance.

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Compounding Chemotherapy Hospitals Drug Development 315

STAT

APRIL 11, 2024

Diagnosed at age 3 with acute myeloid leukemia, an aggressive blood cancer, Logan happened to have a targetable mutation that occurs in a small minority of childhood AML cases, making it possible for him to receive a precision therapy drug that — with chemotherapy — got him to a point where he could receive a bone marrow transplant.

Chemotherapy 362

Chemotherapy Hospitals 362

STAT

SEPTEMBER 14, 2023

WASHINGTON — A nonprofit formed by hospitals to deal with drug shortages is considering a move into chemotherapies. Frustrated by drug shortages and the price spikes that typically ensue, executives from large hospital systems launched the nonprofit Civica Rx to deal with the problem in September 2018.

Hospitals 325

Hospitals Chemotherapy Drug Pricing 325

World Pharma News

FEBRUARY 26, 2024

Despite treatments such as surgery, radiation therapy and chemotherapy, only about a quarter of all people with the disease will live more than five years after diagnosis, and lung cancer kills more than 1.8 Lung cancer is not the most common form of cancer, but it is by far the deadliest.

Chemotherapy 92

Chemotherapy 92

STAT

APRIL 10, 2023

When Jeannette Cleland learned earlier this year that she could get chemotherapy at home, after dropping a particularly toxic medication, it seemed like good news. But then Cleland, a 44-year-old Minneapolis event planner who has stage 4 pancreatic cancer, did the math. Read the rest…

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Chemotherapy 246

STAT

SEPTEMBER 21, 2023

Like many cancer patients, Sarah’s treatment at Dana-Farber was co-managed by its longtime medical partner, Brigham and Women’s Hospital: Her three surgeries were performed at the Brigham, by Brigham doctors; her five rounds of chemotherapy at Dana-Farber. Continue to STAT+ to read the full story…

Chemotherapy 352

Chemotherapy Hospitals 352

STAT

NOVEMBER 30, 2023

Elahere is among a surging class of cancer medicines called antibody-drug conjugates , or ADCs, which are designed to deliver a targeted dose of chemotherapy directly to tumor cells while sparing healthy tissues.

Chemotherapy 356

Chemotherapy 356

European Pharmaceutical Review

JUNE 19, 2024

A non-chemotherapy multi-drug therapy enabled complete remission in 38 percent of evaluable patients with aggressive B-cell lymphoma, a Phase Ib/II clinical trial shows. The post Non-chemotherapy lymphoma treatment may provide durable remission appeared first on European Pharmaceutical Review.

Chemotherapy 98

Chemotherapy 98

STAT

SEPTEMBER 22, 2023

The drug, called datopotamab deruxtecan or Dato-DXd for short, succeeded on one of its primary endpoints of improving progression-free survival compared to chemotherapy in certain breast cancer patients who had previously been treated with other therapies.

Chemotherapy 331

Chemotherapy 331

STAT

SEPTEMBER 11, 2024

Certain cancer therapies like chemotherapy can be harsh on these white blood cells, so cancer patients need their neutrophil count to be in a given range when undergoing those treatments or before enrolling in particular clinical trials. One of the most important measurements for cancer patients is the neutrophil count.

Chemotherapy 318

Chemotherapy 318

STAT

OCTOBER 25, 2023

The other scenario involved treatments that were more expensive, but no more effective than alternatives, such as the Abraxane chemotherapy. Overall, the proportion of patients who were prescribed so-called low-value drugs was higher when their oncologist accepted industry payments, according to the study, published in the BMJ.

Chemotherapy 361

Chemotherapy Pharmaceutical Companies Pharmaceutical Companies 361

STAT

MAY 8, 2024

Among this vulnerable group are people with cancer undergoing chemotherapy, recipients of organ transplants, those with autoimmune conditions, and others.

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Chemotherapy Immunization Immunity 307