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Episode 918: What Happens If You Give a Cephalosporin to a Patient With Moderate, Severe, or Unknown Beta-Lactam Allergy?

Pharmacy Joe

Subscribe on iTunes , Android , or Stitcher The label of “penicillin allergic” usually sticks to a patient’s medical record forever. A 50 y/o male with an SSTI had an unknown allergy to penicillin, received a single dose of ceftriaxone in the ED and was then switched to piperacillin-tazobactam as an inpatient.

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Episode 547: How to predict the pharmacotherapy needs of your patient and team during an inpatient medical emergency

Pharmacy Joe

In this episode, I’ll discuss how to predict the pharmacotherapy needs of your patient and team during an inpatient medical emergency. This is when you do regular pharmacist things like drawing up and labeling medications, and calculating doses. This work is valuable because it frees a nurse up to be hands-on with a patient.

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Episode 852: Does Europe Do Apixaban Renal Dosing Better (Safer) Than the US?

Pharmacy Joe

The US labeling states: Anti-FXa activity adjusted for exposure to apixaban was similar across renal function categories. Using inverse probability of treatment weighting analysis, the US labeling recommendation of apixaban 5 mg was associated with a higher risk of bleeding at an incidence rate 4.9 or greater. mg twice daily.

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Episode 852: Does Europe Do Apixaban Renal Dosing Better (Safer) Than the US?

Pharmacy Joe

The US labeling states: Anti-FXa activity adjusted for exposure to apixaban was similar across renal function categories. Using inverse probability of treatment weighting analysis, the US labeling recommendation of apixaban 5 mg was associated with a higher risk of bleeding at an incidence rate 4.9 or greater. mg twice daily.

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Episode 902: The analgesic ceiling dose of ibuprofen applies to ED patients too

Pharmacy Joe

Back in episode 473 , I talked about the evidence behind the discrepancy between the labeled dose and the analgesic ceiling dose of IV ketorolac. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–

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Episode 821: What dose of inhaled tranexamic acid is used for nonmassive hemoptysis?

Pharmacy Joe

If using this off-label strategy, give preference to the preservative-free version of IV tranexamic acid due to the potential adverse effects of nebulized preservatives. There were no side effects noted in either group throughout the follow-up period. A reduced hemoptysis recurrence rate was noted at the 1-year follow-up (P =.009

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Episode 821: What dose of inhaled tranexamic acid is used for nonmassive hemoptysis?

Pharmacy Joe

If using this off-label strategy, give preference to the preservative-free version of IV tranexamic acid due to the potential adverse effects of nebulized preservatives. There were no side effects noted in either group throughout the follow-up period. A reduced hemoptysis recurrence rate was noted at the 1-year follow-up (P =.009