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Episode 782: Wernicke’s Encephalopathy Treatment During an IV Thiamine Shortage

Pharmacy Joe

However, a study published in 2012 in BMC Clinical Pharmacology challenges that concept and seems to show that at very high doses there must be some form of passive, non-saturable absorption of thiamine. Healthy subjects were given oral thiamine at doses of 100 mg, 500 mg, and 1500 mg.

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Episode 782: Wernicke’s Encephalopathy Treatment During an IV Thiamine Shortage

Pharmacy Joe

However, a study published in 2012 in BMC Clinical Pharmacology challenges that concept and seems to show that at very high doses there must be some form of passive, non-saturable absorption of thiamine. Healthy subjects were given oral thiamine at doses of 100 mg, 500 mg, and 1500 mg.

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Episode 573: Ceiling dose of ketorolac for renal colic in the ED

Pharmacy Joe

In 1989, a study in the Journal of Clinical Pharmacology compared 10, 30, and 90 mg of IM ketorolac with placebo in 126 patients with cancer pain. If you like this post, check out my book – A Pharmacist’s Guide to Inpatient Medical Emergencies: How to respond to code blue, rapid response calls, and other medical emergencies. <–