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EC approves Libtayo® for metastatic cervical cancer

European Pharmaceutical Review

s Libtayo ® (cemiplimab) for adults with recurrent or metastatic cervical cancer and disease progression while on or after platinum-based chemotherapy. “Libtayo ® was the first programmed cell death protein (PD)-1 inhibitor to demonstrate significant improvements in survival compared to chemotherapy in a Phase III trial.

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EC approves Regeneron’s immunotherapy for cervical cancer

Pharmaceutical Technology

Libtayo is also indicated for treating progression of the disease on or following platinum-based chemotherapy. The trial enrolled 608 subjects in 14 countries, regardless of their PD-L1 expression status or histology and assessed Libtayo versus a chemotherapy of investigator's choice.

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FDA Approves Cell Therapy for Patients with Blood Cancers to Reduce Risk of Infection Following Stem Cell Transplantation

LifeProNow

The product is intended for use in adults and pediatric patients 12 years and older with blood cancers planned for umbilical cord blood transplantation following a myeloablative conditioning regimen (treatment such as radiation or chemotherapy). director of the FDA’s Center for Biologics Evaluation and Research.

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Developing point-of-care CAR T manufacturing

European Pharmaceutical Review

Bridging therapy has been shown to correlate with an inferior response to CAR T-cell therapy due to both progression of the chemotherapy-refractory malignant disease during the manufacturing period and increased toxicity. After this incident CAR-related toxicity scales and guidelines were established to prevent adverse reactions.

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FDA slaps hold on trials of Gilead’s CD47 drug magrolimab

pharmaphorum

It covers three phase 3 trials involving subjects with myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML), as well as ‘unfit’ AML patients who are unable to be treated with intensive treatment like high-dose chemotherapy.

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FDA approved KEYTRUDA in combination with chemotherapy for adult patients with endometrial carcinoma

Express Pharma

This is the first Phase 3 trial to statistically evaluate an anti-PD-1 immunotherapy plus chemotherapy combination in patients with pMMR and dMMR tumours as two independent cohorts,” said Dr Ramez N. Early identification and management of immune-mediated adverse reactions are essential to ensure safe use of KEYTRUDA.

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Selenium: The Nutrient That Can Reduce Thyroid Antibodies by 40%

The Thyroid Pharmacist

Selenium is vital to our body’s ability to convert T4 to T3, and has a balancing effect on our thyroid and immune health. There are many different types of selenoproteins that focus on different functions relating to thyroid and immune system support. Why such an impact on so many? This is how autoimmunity starts. percent felt worse.

Dosage 59