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Regeneron, CytomX announce bispecific therapeutics for cancer collab

pharmaphorum

Dr John Lin, senior vice president of immune-oncology and head of bispecifics at Regeneron , said: “The collaboration will enable Regeneron and CytomX to combine our collective oncology expertise with two premier platforms […] to develop novel immunotherapies and research their potential to transform patient lives.”.

Immunity 105
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Daiichi Sankyo poised to add another ADC blockbuster with datopotamab deruxtecan for non-squamous NSCLC: GlobalData

Express Pharma

billion by 2029. “ There are multiple Phase III studies for the ADC in frontline NSCLC in combination with immune checkpoint inhibitors such as Merck’s Keytruda (pembrolizumab) or AstraZeneca’s Imfinzi (durvalumab). billion in 2023, and GlobalData projects it to surpass $14 billion by 2029.

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The future of pain medication: are cannabinoids the solution to the opioid epidemic?

Pharmaceutical Technology

In 2022, the FDA awarded VX-548 breakthrough therapy and fast-track designations for post-operative pain, and the drug is forecast to reach sales of $416m by 2029. CB1 is predominantly found in the central and peripheral nervous system, whereas CB2 is primarily located in immune cells.

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AstraZeneca to advance haematology cell therapy

European Pharmaceutical Review

According to the research, the global cell and gene therapy market is predicted to value $80 billion by 2029. AstraZeneca highlighted that beneficially, the Gracell FasTCAR platform significantly shortens manufacturing time, enhances T cell fitness and could improve the effectiveness of autologous CAR-T treatment in patients.

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Managing the next pandemic: the role of nasal vaccine administration

European Pharmaceutical Review

1 This novel approach has been found to trigger robust protective immune responses at the predominant sites of pathogen infection. million by 2029, up from $122.287 million in 2021. Recent studies indicate that mucosal delivery of vaccines provides a better, longer-lasting effect than the traditional injection route.

Vaccines 119
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AstraZeneca acquires TeneoTwo in $1.3bn deal to broaden haematology portfolio

Pharmaceutical Technology

Moreover, a deeper understanding of immune evasion by cancer cells may provide novel sensitization strategies to further enhance the clinical response of BiTEs. . Currently, there are 110 BiTEs in oncology clinical trials, with seven in Phase III and three in pre-registration.

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Advancing clinical development in haematology oncology

European Pharmaceutical Review

billion by 2029. 2 One of the challenges that we have in treating cancer is that the human immune system is highly complex. This requires modulating different components of the human immune system in a way that can address different patient segments, as the immune system is dysregulated in different ways across different tumour types.