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STAT+: Pharmalittle: We’re reading about a key Merck drug trial, cheap Wegovy in China, and more

STAT

patent expires in 2028. Keytruda is a cancer immunotherapy, which stimulates the immune system to attack tumor cells and is the best-selling medicine in the world. The subcutaneous injection could be given in a doctor’s office every six weeks, instead of requiring a 30-minute IV drip at the same interval.

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STAT+: Merck to acquire Harpoon Therapeutics for $680 million

STAT

Merck announced Monday it will acquire Harpoon Therapeutics and its pipeline of immune-based cancer drugs for $680 million. That could come as soon as 2028. Keytruda, a PD-(L)1 inhibitor, works by turning off a “brake” on T cells, allowing roving immune cells to attack tumors.

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mRNA non-vaccine therapeutics to generate $2 billion by 2028

European Pharmaceutical Review

According to GlobalData’s recent report , a total of five marketed messenger RNA (mRNA) non-vaccine products by 2028 will generate over $2 billion, generated by the approval of pipeline agents. billion during 2028.

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Immuno-oncology market set to grow in billions, but access concerns remain

Pharmaceutical Technology

was powered by the advent of immune-checkpoint inhibitors, added Chalk. These figures are only expected to grow in the coming years, with sales forecasted to reach over $150 billion by 2028. Checkpoint modulators, cytokines and oncolytic viruses are also considered as part of the overall immune-oncology field.

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HepaStem seems most promising pipeline agent for decompensated cirrhosis due to NASH: GlobalData

Express Pharma

tumor formation, immune reactions, and therapy failure). HepaStem is projected to hit the US market in Q1 2027, while BioVie’s BIV201 is anticipated to be marketed in Q4 2028. Albutein appears to be on track to be the first therapeutic approved for DC, with a projected US launch date in Q1 2026.

Diabetes 111
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Key developments: mRNA vaccines and therapeutics

European Pharmaceutical Review

Initially developed to treat viral infections, mRNA vaccines deliver a piece of genetic material that instructs the body to make a protein fragment of a target pathogen (such as a virus), which the immune system recognises and remembers 1 to respond to when exposed to the pathogen in the future.

Vaccines 105
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A history of blood cancer treatment

pharmaphorum

Crucially, he observed a connection between certain tumours and inflammation, noting that neoplastic tissues were often covered with leukocytes of the immune system. Building on the success of cytokine-based immunotherapies, scientists continued to seek other areas where the immune system could be leveraged against tumours.