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China poised to lead the way with world’s first oral insulin for type 2 diabetes: GlobalData

Express Pharma

Hefei Tianhui Biotechnology (HTIT) has recently submitted a marketing authorisation application (MAA) in China for the world’s first oral insulin for type 2 diabetes (T2D). The number of diagnosed prevalent cases of type 2 diabetes in China is estimated to grow at a CAGR of 2.21 million in 2028, as per GlobalData.

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STAT+: Pharmalittle: We’re reading about Moderna R&D cuts, Lilly plant investments and more

STAT

In a press release issued ahead of an investor meeting today, the company also said it plans to break even by 2028, when it expects it will reach annual sales of $6 billion. … Moderna plans to cut its annual spending on research and development by 23%, or $1.1 The stock was trading 3.5%

Packaging 146
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Innovent Biologics mazdutide can pave way for transformative T2D treatment: GlobalData

Express Pharma

Innovent Biologics has unveiled Phase III (DREAMS-2) results for mazdutide, indicating superiority over dulaglutide in glycaemic control for type 2 diabetes (T2D) patients in China. per cent from 58.460,424 in 2023 to 63,342,654 in 2028. Dual agonism at GLP-1R and GCGR could potentially enhance efficacy beyond monotherapies.”

Diabetes 104
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AZ gets European approvals for Forxiga in chronic kidney disease

pharmaphorum

The European Commission has cleared Forxiga (dapagliflozin) for CKD in adults with or without diabetes, and the drug becomes the first new drug treatment for these patients in more than two decades. GlobalData has said Farxiga will reach peak sales of $9 billion in 2028, with Jardiance forecast to reach $4.6

Diabetes 111
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NICE backs AZ’s Forxiga for heart failure

pharmaphorum

Forxiga (dapagliflozin) – originally developed as a type 2 diabetes drug – is the first SGLT2 inhibitor to be approved for the treatment of symptomatic chronic heart failure with reduced ejection fraction (HFrEF) in adults with and without diabetes. billion, assuming a launch for HFrEF in 2021.

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Farxiga faces first heart failure rival as EU OKs Boehringer/Lilly’s Jardiance

pharmaphorum

Jardiance, Farxiga (dapagliflozin) and other SGLT2 drugs are already widely used to treat type 2 diabetes, and their developers have long had aspirations to expand their use into other cardiometabolic disorders, including heart failure and chronic kidney disease (CKD).

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Innovating small molecule injectables: market forecast to 2033

European Pharmaceutical Review

billion in 2028. million deaths from diabetes” worldwide. A report by the Business Research Company predicts that the small molecule injectable drugs market will value $355.14 As such, the compound annual growth rate (CAGR) is expected to be 12.8 percent up to this period. million deaths from cardiovascular diseases, 9.3