Remove 2028 Remove Compounding Remove Drug Development
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Understanding Large Molecule Drug Development: From Biologics to Market

Syner-G

This shift from a linear to a network approach enhances the potential for one drug to target multiple sites. Structure-based drug design has evolved, facilitating the exploration of novel chemical probes and lead compound potency, and molecular docking utilizes target structures to predict interactions and offers simplicity and speed.

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Psychedelic drug market to reach $7.2 bn in 2029: GlobalData

Express Pharma

The psychedelic drug market is on the brink of extraordinary growth, projected to soar to $7.2 billion by 2029, reflecting a robust 55 per cent compound annual growth rate (CAGR). This ascent is propelled by favorable regulatory developments, including pioneering clinical trial guidelines from the FDA. billion in sales in 2029.

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Oncology market dominance: As easy as ADC?

pharmaphorum

The potential for ADCs to combine the best of both mAbs and small molecule drugs means that there has been high interest in developing a successful compound since the first successful clinical trial in 1983. At present, there are 12 approved treatments and the development work being done to bring more through is only increasing.

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There is a large pipeline of CAR-T cell therapies for diffuse large B-cell lymphoma

Pharmaceutical Technology

By 2028, the market is expected to reach $25 billion, with a compound annual growth rate (CAGR) of 46.6%. Notable Phase II drugs include Allogene Therapuetics’s ALLO-501A, Autolus Therapeutics’s obecabtagene autoleucel, CASI Pharmaceuticals’s CNCT-19, Precision Biosciences’s PBCAR-0191, and Mustang Bio’s MB-106.

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PROTAC development gains momentum, but clinical performance is poor

Pharmaceutical Technology

This makes early R&D less risky, as many lead compounds are discontinued due to inadequate pharmacokinetic profiles and require excessively high dosages to be pharmaceutically active. Both degraders, ARV-110 (bavdegalutamide) and ARV-766, are being developed by Arvinas.

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Antibody-drug conjugates gain traction in China oncology market: GlobalData

Express Pharma

The diagnosed prevalent cases of gastric, breast, and bladder cancers in China are expected to increase at a compound annual growth rate (CAGR) of 2.6 per cent, and 3 per cent, respectively, between 2022 and 2028. These companies have active research and development collaborations with various local players worldwide.