STAT

OCTOBER 8, 2024

appeals court ruled 2-1 that Merck is immune from an antitrust lawsuit accusing it of misleading regulators about the effectiveness of its mumps vaccine in order to ward off competition, Reuters says. from 1967 until 2022. ” A U.S.

Compounding 256

Compounding Compounding Pharmacies Vaccines Immunity 256

Express Pharma

NOVEMBER 28, 2024

According to GLOBOCAN 2022 statistics, the number of newly diagnosed NPC cases in 2022 exceeded 120,000 worldwide. In India, there were 6,519 newly diagnosed cases of NPC in 2022 (3). Blocking PD-1 interactions with PD-L1 and PD-L2 promotes the immune system’s ability to attack and kill tumour cells (5).

Chemotherapy 111

Chemotherapy Immunity Immunization 111

pharmaphorum

SEPTEMBER 23, 2020

Shares in AC Immune have collapsed after partner Genentech revealed its tau-targeting Alzheimer’s drug semorinemab had flunked a phase 2 trial in Alzheimer’s disease (AD). TauRx has stuck with the programme however, starting a phase 2/3 trial with results due next year or in 2022.

Immunity 64

Immunity Immunization 64

Pharmaceutical Technology

SEPTEMBER 14, 2022

Before TIL infusion, the patient undergoes lymphodepletion, which reduces the proportion of myeloid immune suppressive cells and creates space for the incoming lymphocytes. The high level of neoantigens in melanoma makes this the ideal setting for TIL therapy, with tumours often containing multiple clones of tumour-reactive immune cells.

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Immunity Immunization 98

BioPharma Dive

JULY 23, 2024

Peter Lebowitz, who for years led J&J’s oncology R&D, is the CEO of the startup, called Third Arc Bio and launched by Omega Funds in 2022.

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Immunity Immunization 85

European Pharmaceutical Review

AUGUST 10, 2022

On 23 July 2022, the World Health Organization (WHO) Director-General, Dr Tedros Adhanom Ghebreyesus, declared the multi-country outbreak of monkeypox a public health emergency of international concern. As of 2 August 2022, the UK had 2,739 confirmed cases, 4 the majority occurring within London, England. Current case rates.

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Vaccines Immunity Immunization Labelling 96

Pharmacy Is Right For Me

OCTOBER 11, 2022

We’re thrilled to announce the winners of the 2022 CVS Health Minority Scholarship for Pharmacy Students! The 2022 CVS Health Minority Scholarship for Pharmacy Students winners We connected with each of the 2022 scholarship awardees to discuss how this scholarship will help them move forward in pursuing a career in pharmacy.

Immunity 130

Immunity Immunization 130

pharmaphorum

SEPTEMBER 16, 2022

A mere six months ago Verily launched the study with Sosei Heptares – a global leader in GPCR structure-based drug design – with an aim to “prioritise protein targets for therapeutic targeting in immune-mediated disease”. Verily’s Immune Profiler can, Kim asserted, “generate more than 8 million immune measures across 24 immune cell subsets”.

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Immunity Immunization Drug Development 135

European Pharmaceutical Review

JANUARY 23, 2023

EVX-01 cancer immunotherapy EVX-01 is a peptide-based cancer immunotherapy generated based on gene analysis of a patient’s tumours and on matching with their immune system. In December 2022, results from that trial (NCT03897881) were shown to improve recurrence-free survival (RFS) in melanoma patients. Moderna, Inc.

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Immunity Immunization Vaccines 124

European Pharmaceutical Review

JULY 18, 2022

Some people with haemophilia may also develop inhibitors, antibodies that are an immune response to the clotting factors in replacement therapy that cause the treatment to stop working. Dosing in the Phase III study is expected to start in the fourth quarter of 2022. Novo Nordisk – concizumab and Mim8. compared to 11.8

Immunity 98

Immunity Immunization Hospitals 98

European Pharmaceutical Review

DECEMBER 12, 2023

He discusses why NK cell therapy’s ability to generate ‘synthetic immunity’ in the body means this modality holds potential as an anti-cancer treatment. We specialise in the development of new cutting-edge immunotherapies , based on the use of therapeutic antibodies capable of activating the immune system to fight cancer.

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Immunity Immunization Chemotherapy Pharmaceutical Companies 124

Express Pharma

APRIL 17, 2023

Prometheus is a clinical-stage biotechnology company pioneering a precision medicine approach for the discovery, development, and commercialisation of novel therapeutic and companion diagnostic products for the treatment of immune-mediated diseases.

Immunity 98

Immunity Immunization Research Laboratories Labelling 98

European Pharmaceutical Review

AUGUST 2, 2023

This is an additional ingredient designed to trigger a stronger immune response. The vaccine demonstrated a strong immune response in the trial. In August 2022, the MHRA approved Moderna’s adapted vaccine for COVID-19, Spikevax bivalent Original/Omicron as a booster treatment.

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Vaccines Immunity Immunization 98

Express Pharma

AUGUST 23, 2023

The study was performed to understand whether the immunity gained after vaccination or a prior infection was less effective or “leaky” in situations where people are exposed to high levels of the virus.

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Vaccines Documentation Immunity Immunization 98

European Pharmaceutical Review

AUGUST 3, 2022

Current vaccines often employ a B-cell immune response through the production of specific antibodies that target the virus’ surface, which can be highly prone to mutation. The adaptive immune response to a natural infection. The adaptive immune response to a natural infection.

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Vaccines Immunity Immunization 95

European Pharmaceutical Review

JULY 13, 2023

The field of immunotherapy is constantly evolving with the ultimate goal to develop new treatments that help the body’s immune system fight cancer. Immune cells, such as T cells and natural killer (NK) cells, have the inherent ability to combat diseases, including cancer, but are often inhibited by the body’s own suppressive mechanisms.

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Immunity Immunization Hospitals 98

Express Pharma

MARCH 29, 2023

The statement informed that the company has achieved the following: Closing the micronutrient gap of 642 million vulnerable people in 2022 through the fortification for staple foods, public health initiatives, and emergency relief supplements. The company aims to support 500 million people by 2030.

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Immunity Immunization 96

Express Pharma

JULY 1, 2024

The submission was based on positive data from a late-stage trial that showed the drug reduced the risk of infection in patients with weaker immunity. AstraZeneca acquired sipavibart from RQ Bio in May 2022. An accelerated assessment aims to speed up the EMA’s review of a market authorisation application.

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Vaccines Immunity Immunization 103

Express Pharma

NOVEMBER 13, 2024

Simi Badyal MSc, Senior Competitive Intelligence Immunology Analyst at GlobalData, comments: “CAR T cell therapies have gained immense traction in recent years within immunology and autoimmune diseases, driven by promising results from the Georg Schett study, first published in 2022.”

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Immunity Immunization 105

Express Pharma

JUNE 9, 2024

4) The regulatory application was supported by positive results from a phase III trial [NCT05590403] (5) evaluating the immune response and safety of GSK’s RSV vaccine in adults aged 50-59, including those at increased risk for RSV-LRTD due to certain underlying medical conditions.

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Vaccines Immunity Immunization Diabetes 111

Digital Pharmacist

OCTOBER 24, 2022

Date of Approval: 9/30/2022. Date of Approval: 9/29/2022. Date of Approval: 9/22/2022. Date of Approval: 9/21/2022. Date of Approval: 9/14/2022. Date of Approval: 9/9/2022. Below we will be listing some of the new drug therapy advances and approvals that the FDA had in the month of September.

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Adverse Reactions Labelling Pharmacy Management Immunity 75

pharmaphorum

MAY 19, 2022

It codes for an antigen called eOD-GT8 60mer and, in the study, stimulated a targeted B-cell immune response in 97% of vaccine recipients. — Moderna (@moderna_tx) May 18, 2022. One candidate – mRNA-1644 – has already shown its potential in an earlier phase 1 trial (IAVI G001) run in the US.

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Vaccines Immunity Immunization 145

pharmaphorum

NOVEMBER 29, 2022

Amplifying and reinvigorating persistent T cell immunity has become a much-needed path to enhance anti-tumor efficacy. T cells are known to mediate anti-tumor immune responses. For that reason, they have become the key target of immune checkpoint therapies, like PD-(L)1 agents. Suite 250, Rockville, MD 20850). Creation: Jan.

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Immunity Immunization Chemotherapy Compounding 105

European Pharmaceutical Review

AUGUST 16, 2022

The MHRA’s decision is based on data from a clinical trial which showed that a booster dose of the bivalent Moderna vaccine triggers a strong immune response against both Omicron (BA.1) In an exploratory analysis the bivalent vaccine was also found to generate a good immune response against the Omicron sub-variants BA.4

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Vaccines Immunity Immunization 105

Pharmaceutical Technology

SEPTEMBER 13, 2022

The advent of immune checkpoint inhibition has arguably been the greatest breakthrough for the treatment of metastatic solid tumours, with durable complete responses observed across multiple cancer types. The post ESMO 2022: neoadjuvant or adjuvant immunotherapy for locally advanced cancers?

Immunity 69

Immunity Immunization Chemotherapy 69

European Pharmaceutical Review

SEPTEMBER 26, 2022

At the 2022 European Society for Medical Oncology Congress (ESMO) conference, promising results from a Phase I trial, suggesting that a novel genetically modified (GM) herpes virus eradicated or reduced advanced cancers, were presented.

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Immunity Immunization 98

Pharmaceutical Technology

NOVEMBER 14, 2022

Such developments, including a 2021 approval of AstraZeneca’s Saphnelo (anifrolumab) , prompted The Lancet Rheumatology to posit that 2022 could be a “banner year” for the condition. In lupus, the body’s immune system starts to attack its own cells. MSCs and CAR-Ts for lupus.

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Immunity Immunization 144

FDA Law Blog: Biosimilars

APRIL 30, 2023

Senate Committee on Health, Education, Labor and Pensions (“Senate HELP”) is scheduled to take up legislation that could significantly limit access to the courts and immunize critical FDA decisions from timely judicial review. 1067, which first reared its head in Spring 2022 as an amendment to S.4348, Shumsky — On May 2nd, the U.S.

Immunity 59

Immunity Immunization Biosimilars Labelling 59

pharmaphorum

DECEMBER 4, 2020

First data from the study is expected by the second quarter of 2022 and all three studies will support a phase 3 pivotal efficacy trial including all main target populations for the Lyme vaccine, starting in 2022. VLA15 has demonstrated a promising immune response and safety data in pre-clinical and clinical studies so far.

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Vaccines Immunity Immunization 119

Pharmaceutical Technology

JUNE 12, 2023

In 2022, the FDA awarded VX-548 breakthrough therapy and fast-track designations for post-operative pain, and the drug is forecast to reach sales of $416m by 2029. CB1 is predominantly found in the central and peripheral nervous system, whereas CB2 is primarily located in immune cells.

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Immunity Immunization Drug Development 143

pharmaphorum

JANUARY 13, 2022

The increased immune response was seen in people who received AZ’s shot as their primary vaccination as well as mRNA vaccines, said the drugmaker, which said the data “add to the growing body of evidence supporting Vaxzevria as a third dose booster.”

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Vaccines Immunity Immunization 98

pharmaphorum

NOVEMBER 11, 2022

Marc Pelletier , Senior Principal Scientist – Translational Immune Oncology, Novartis. Kate Fitzgerald , Professor & Vice Chair, Department of Medicine, Division of Innate Immunity, University of Massachusetts Chan Medical School. The post 4th Inflammasome Therapeutics Summit 2022 appeared first on.

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Medical Schools Immunity Immunization Hospitals 52

European Pharmaceutical Review

AUGUST 25, 2022

IN 2022, treating glioblastoma (GBM) remains an uphill battle. This strategy has failed to gain a foothold in the past as the patient’s immune system interferes, destroying the unprotected oncolytic viruses. The remaining missing piece of the puzzle has been how to shield them from destruction by the immune system.

Immunity 111

Immunity Immunization Chemotherapy Packaging 111

Pharmaceutical Technology

MAY 22, 2023

It can suppress Th2 immune responses by binding to IL-17RB on Type 2 innate lymphoid cells (ILC2s). In March 2022, the US Food and Drug Administration approved the IND application for SM17 to treat asthma. In March 2022, the US Food and Drug Administration approved the IND application for SM17 to treat asthma.

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Immunity Immunization Drug Development 109

European Pharmaceutical Review

JANUARY 4, 2024

Immunotherapy drugs like teclistamab can result in potentially fatal side effects, including CRS and immune cell-associated neurotoxicity syndrome (ICANS). An overactive immune response [is] the hallmark of CRS,” Landgren added. In 2022, the drug was approved by the US Food and Drug Administration (FDA) for these patients.

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Immunity Immunization Hospitals Drug Development 97

pharmaphorum

JANUARY 10, 2023

Other IgG proteases are being developed to tackle the issue of pre-existing immunity against AAV, but according to Selecta chief executive Carsten Brun these tend to be derived from common human pathogens – which means they themselves can be the target of existing antibodies.

Immunity 119

Immunity Immunization Drug Development 119

pharmaphorum

FEBRUARY 9, 2022

Using a vaccine to utilise the patient’s own immune system to fight cancer is particularly attractive because of the targeted approach made possible by this technology. While therapeutic cancer vaccines are able to help the body identify particular proteins expressed by cancer cells and then to instigate an immune response.

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Vaccines Immunity Immunization Compounding 134