STAT

MARCH 28, 2024

While an increasingly anxious world watched a new coronavirus spread across the globe in early 2020, veteran immunologist Rafi Ahmed quickly grasped that his field was about to experience something truly extraordinary.

Immunity 364

Immunity Immunization Vaccines 364

STAT

OCTOBER 16, 2024

But the underlying message to doctors in late 2020 was persistent and urgent: Hit your targets to see more patients. At the time, deaths from Covid-19 were surging, and no vaccine was available. The emails from UnitedHealth Group managers were filled with exclamation marks and pleasantries about the weather.

Documentation 363

Documentation Vaccines 363

STAT

OCTOBER 2, 2023

Overcoming a lack of broader interest in their work and scientific challenges, Katalin Karikó and Drew Weissman made key discoveries about messenger RNA that enabled scientific teams to start developing the tool into therapies, immunizations, and — as the pandemic spread in 2020 — vaccines targeting the SARS-CoV-2 coronavirus.

Immunity 363

Immunity Immunization Vaccines 363

Express Pharma

DECEMBER 11, 2024

per cent from $582 million in 2020 to $6.2 GlobalDatas latest report, Respiratory Syncytial Virus Prophylaxis: Eight-Market Drug Forecast and Market Analysis Update, reveals that market growth will primarily be driven by the uptake of new monoclonal antibodies (mAbs), as well as maternal, adult, and pediatric RSV vaccines.

Vaccines 102

Vaccines Compounding 102

STAT

MAY 23, 2023

WASHINGTON — The incarcerated people at Federal Medical Center Devens should have been some of the first to receive the Covid vaccines, back when they first came out in December 2020. At the time, the country was prioritizing high-risk people in high-risk settings, like older Americans in nursing homes.

Nursing Homes 253

Nursing Homes Vaccines 253

STAT

JULY 19, 2024

He often appeared on public service announcements in a white lab coat emblazoned with“N-Y-C” in big, bold letters, urging urbanites to mask up , get tested , and get vaccinated. Read the rest…

Vaccines 258

Vaccines Hospitals 258

STAT

APRIL 19, 2023

The calamity of March 2020 arrived two years later for pediatric units.

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Vaccines Hospitals 233

STAT

OCTOBER 25, 2022

As MacArthur Foundation fellow Jennifer Richeson noted in The Atlantic in 2020, Americans love to perpetuate narratives of racial progress , regardless of whether that narrative is aligned with reality. We saw this in a recent New York Times essay that claimed the change in Covid-19 death rates is a laudable example of the U.S.

Vaccines 267

Vaccines 267

Outsourcing Pharma

MARCH 3, 2021

The 2020 Pfizer/BioNTech COVID-19 vaccine trial recruited more than 44,000 participants and reached submission for emergency authorization in 248 days: showing unprecedented speed and agility in the context of a global pandemic.

Vaccines 136

Vaccines 136

pharmaphorum

JUNE 21, 2021

It would be easy to forget that back in 2019, BioNTech was an early-stage biotech firmly focused on cancer vaccines, before being catapulted onto the world-stage with its COVID-19 shot. Among the 25-strong group given the vaccine on its own, there was one patient who had a complete remission of tumours that had spread from the original site.

Vaccines 145

Vaccines Immunity Immunization 145

Pharma Times

DECEMBER 15, 2020

The trial is expected to begin next month, with first data anticipated in the second quarter of 2020

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Vaccines 168

Express Pharma

JANUARY 23, 2025

Since the first designation in 1984, the FDA has seen a substantial rise in the number of designations granted, reaching 694 in 2020. The period between 2012 and 2020 saw another rapid increase in the annual numbers of review designations awarded. In 2020, the number of designations awarded reached a peak of 694.

Vaccines 104

Vaccines Drug Development 104

STAT

MARCH 6, 2023

Still, when doctors told her last year that the cancer was growing despite two operations, radiation therapy, and a fifth regimen of chemotherapy, the retired business-meeting facilitator decided to do something unorthodox: spend $83,000 out of pocket on an unproven experimental cancer vaccine.

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Vaccines Bioethics Immunity Immunization 246

Pharmaceutical Technology

JANUARY 29, 2024

The rapid sequencing of the SARS-CoV-2 and the subsequent development of mRNA vaccines led to the authorisation of the first of these vaccines in late 2020.

Vaccines 111

Vaccines 111

pharmaphorum

MARCH 16, 2021

European regulators questioned the integrity of early batches of Pfizer/BioNTech’s mRNA vaccine, although the matter was resolved before approval, according to information leaked online following a cyberattack. As it conducted its analysis of the vaccine in December, the European Medicines Agency’s systems were targeted by unknown hackers.

Vaccines 138

Vaccines Documentation 138

STAT

OCTOBER 3, 2022

… Moderna refused to hand over to China the core intellectual property behind the development of its Covid-19 vaccine, leading to a collapse in negotiations on its sale there , The Financial Times reports. Moderna was pressed to take the former option. Continue to STAT+ to read the full story…

Drug Pricing 234

Drug Pricing Vaccines 234

pharmaphorum

FEBRUARY 9, 2022

In this article, Ben Hargreaves looks into the promise of cancer vaccines and how this treatment modality may offer advantages over existing immunotherapies in the oncology sector. One area that is gathering increasing levels of interest is the development of cancer vaccines. over the last five years. A broad front.

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Vaccines Immunity Immunization Labelling 134

ALiEM - Pharm Pearls

JANUARY 12, 2024

A 42-year old Bengali man with a history of hyperlipidemia presented to the Emergency Department with facial swelling, diffuse rash, renal insufficiency and proteinuria after receiving his COVID-19 vaccine (Moderna) booster dose. Erythema multiforme has been reported as a cutaneous reaction after the COVID-19 mRNA vaccine.

Vaccines 130

Vaccines 130

European Pharmaceutical Review

AUGUST 16, 2022

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has approved an updated version of Moderna’s COVID-19 vaccine, Spikevax, that targets two coronavirus variants as a booster. The regulator confirmed that the vaccine meets its standards of safety, quality and effectiveness. 1) and the original 2020 strain.

Vaccines 105

Vaccines Immunity Immunization 105

European Pharmaceutical Review

MAY 9, 2024

Withdrawal of the marketing authorisation for the COVID-19 vaccine (ChAdOx1-S [recombinant]) Vaxzevria (SRD) by the European Medicines Agency on 7 May, follows a request by AstraZeneca. Global demand for all COVID vaccines is now much lower and overall supply exceeds demand.

Vaccines 110

Vaccines 110

STAT

SEPTEMBER 11, 2024

No medications are currently approved for the treatment of obesity in children under age 12, though Saxenda was approved for adolescents in 2020 and for adults in 2014. While there were no safety concerns, the trial for a therapeutic vaccine to treat the herpes simplex virus failed to meet its efficacy objective.

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Vaccines 136

Express Pharma

MARCH 23, 2023

China has approved its first domestically developed mRNA vaccine against COVID-19, CSPC Pharmaceutical Group said. China, whose home-grown vaccines are seen as less effective than the Moderna and Pfizer-BioNTech mRNA shots, has been racing to develop vaccines using messenger RNA (mRNA) technology since early 2020.

Vaccines 111

Vaccines 111

Pharmaceutical Business Review

AUGUST 14, 2024

The vaccine candidate is a virus-like particle (VLP)-based, adjuvanted vaccine designed for active immunisation against chikungunya virus (CHIKV) infection. The US regulator will make a decision on the vaccine approval under the Prescription Drug User Fee Act (PDUFA) by 14 February 2025.

Vaccines 105

Vaccines 105

European Pharmaceutical Review

NOVEMBER 1, 2023

In July 2022, the World Health Organization (WHO) released its inaugural report on the pipeline of vaccines currently in development to prevent infections caused by antimicrobial resistance (AMR) bacterial pathogens. WHO referred to 61 bacterial vaccine candidates in diverse stages of clinical development. 1 WHO’s analysis was stark.

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Vaccines Immunity Immunization Drug Development 115

Eye on FDA

JANUARY 6, 2021

During 2020, FDA was able to approve 53 – not surpassing the 2018 all time record of 59, but certainly an admirable second place. Notably, the 2020 NME approvals included 22 related to oncology, with 2 new GIST treatments, 3 in breast cancer and 2 approvals in prostate cancer. That, however, was not really the case.

Compounding 82

Compounding Vaccines 82

STAT

MAY 14, 2024

clinical trial for the AstraZeneca Covid-19 vaccine is suing the company, claiming it left her “permanently disabled,” The Telegraph writes. made vaccine was tested in clinical trials but never approved for use. An American woman who took part in the U.S. Her lawsuit is thought to be the first of its kind in the U.S.,

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Vaccines 220

Pharmaceutical Technology

AUGUST 17, 2022

On August 8, Pfizer and Valneva announced the initiation of a Phase III study with their Lyme disease vaccine , bringing the prospect of an injection to prevent the condition disease one step closer to reality. This means that the vaccine works against multiple serotypes of the disease, she explains. In June 2022, Pfizer acquired 8.1%

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Vaccines 119

pharmaphorum

DECEMBER 23, 2020

It has been a year dominated by the pandemic and many life sciences research projects were put on hold as big pharma turned its attention to vaccines and therapies. However, 2020 did not provide a definitive answer to the biggest question in neurology – which is whether pharma can produce a marketable that can slow the onset of Alzheimers.

Chemotherapy 93

Chemotherapy Compounding Vaccines 93

Express Pharma

JANUARY 29, 2024

The global messenger ribonucleic acid (mRNA) vaccines market currently consists entirely of vaccines for COVID-19. The rapid sequencing of the SARS-CoV-2 viral genome and the subsequent development of mRNA vaccines in response to the pandemic led to the authorisation of the first of these vaccines in December 2020.

Vaccines 110

Vaccines 110

Express Pharma

APRIL 7, 2023

People exposed to higher levels of air pollution before the pandemic had lower antibody responses to COVID-19 vaccines, according to a study. Air pollutants have been shown to affect immune responses, so in this study we wished to determine whether air pollution also affects antibody responses to COVID-19 vaccines,” said Kogevinas.

Vaccines 110

Vaccines Immunity Immunization Diabetes 110

Express Pharma

OCTOBER 16, 2024

Messenger ribonucleic acid (mRNA)-based innovator pharmaceuticals saw a staggering 800 per cent increase in licensing agreement deal values from 2019 to 2024YTD, driven by the remarkable success of mRNA vaccines during the COVID-19 pandemic. GSK and CureVac restructured their 2020 collaboration into a new licensing agreement worth up to $1.57

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Vaccines Immunity Immunization Diabetes 104

pharmaphorum

SEPTEMBER 14, 2020

AstraZeneca has resumed UK trials for its coronavirus vaccine, after the country’s medicines regulator gave the all-clear following a safety scare. Good news for everyone the Oxford vaccine trials are back up and running. We will back our scientists to deliver an effective vaccine as soon as safely possible [link].

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Vaccines Immunity Immunization 102

Pharmaceutical Technology

SEPTEMBER 7, 2022

Indian company Bharat Biotech International has secured approval from Central Drugs Standard Control Organisation (CDSCO) under Restricted Use in Emergency Situation for its intranasal Covid-19 vaccine, iNCOVACC (BBV154), for usage in people aged 18 years and older. It is formulated to permit intranasal delivery via nasal drops.

Vaccines 105

Vaccines 105

Pharmaceutical Technology

APRIL 11, 2023

The US government is reportedly investing more than $5bn in a programme to accelerate the development of new Covid-19 vaccines and treatments. Health experts have lent their support to the new programme as the existing vaccines may not be as effective against future virus threats.

Vaccines 105

Vaccines Immunity Immunization 105

European Pharmaceutical Review

JULY 11, 2022

The novel coronavirus vaccine has been developed at Caltech and The University of Oxfor d. Funding of up to $30 million will support vaccine design, its development through Phase I trials and regulatory activities. . The novel vaccine, which is based on mosaic?8 How the novel coronavirus vaccine works. The novel vaccine?is

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Vaccines Immunity Immunization 98

pharmaphorum

DECEMBER 10, 2020

The US government’s coronavirus vaccine chief has said that Pfizer/BioNTech’s vaccine could carry a warning that it should be avoided by people who are prone to serious allergic reactions. Both recovered after appropriate treatment. Both are recovering well.”.

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Vaccines Documentation 103

European Pharmaceutical Review

DECEMBER 19, 2023

Many of today’s vaccines are produced in ready-to-inject liquid formulations that must be kept cold to maintain stability. However, this greatly complicates both the worldwide distribution and stockpiling of vaccines and other drugs. A requisite cold chain has been designed and implemented to be uninterrupted from factory to patient.

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Vaccines Communication Immunity Immunization 111