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STAT+: Why Orexo is abandoning a digital therapeutic for depression

STAT

Swedish pharmaceutical company Orexo will no longer pursue an app for treating depression after many years of struggling to sell it. Orexo announced this week that it will no longer license the product, called Deprexis, from German manufacturer GAIA.

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STAT+: Belgian anti-trust authorities probe Roche for allegedly delaying biosimilars of two cancer meds

STAT

In a brief statement , the Belgian Competition Authority alleged that Roche offered financial incentives to hospitals between 2017 and 2020 to deter them from considering competitive bids from other pharmaceutical companies that could supply similar medicines.

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STAT+: After four patients died of gene therapy, Astellas sees possible explanation — and a way forward

STAT

The treatment, made by the Japanese pharmaceutical company Astellas, led to severe and fatal liver problems for four of the 24 treated children with X-linked myotubular myopathy, or XLMTM, a genetic disease that severely degrades muscle function and kills most patients before the age of 10.

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STAT+: Wyden decries ‘astonishingly low’ tax rates for pharma companies as he probes business maneuvers

STAT

Thanks to changes in tax law six years ago, several of the largest pharmaceutical companies saw their tax rates fall substantially, but they also reported that most of their profits were shifted offshore in an effort to avoid paying U.S. in 2020, down from 19.6% in 2020, down from 19.6% Senate Committee.

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Optimizing Your Drug Patent Strategy: A Comprehensive Guide for Pharmaceutical Companies

Drug Patent Watch

Drug patents are a form of intellectual property protection that grants pharmaceutical companies exclusive rights to manufacture, sell, and profit from their innovations for a set period. This exclusivity is the lifeblood of the industry, allowing companies to recoup their substantial R&D investments and fund future discoveries.

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STAT+: The once-hot market for biotech jobs and lab space has cooled. What now?

STAT

When Crystal Shih Byers left her job at Novartis in 2020, she was excited to make the leap into a smaller startup. But pharmaceutical companies are large and complex, and she craved more immediate impact. Byers had spent almost nine years at Novartis, most recently helping lead a group that worked on gene therapy.

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STAT+: Ionis blazed trails in genetic medicine. On the cusp of a major approval, can it also be a commercial success?

STAT

For more than 30 years, Ionis developed all of its medicines in partnership with large pharmaceutical companies. “The business model was to partner everything,” said CEO Brett Monia, who took the reins in 2020 and implemented the new strategy. This isn’t just a drug approval, but a major strategic shift.