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Covid’s scientific silver lining: A chance to watch the human immune system respond in real time

STAT

While an increasingly anxious world watched a new coronavirus spread across the globe in early 2020, veteran immunologist Rafi Ahmed quickly grasped that his field was about to experience something truly extraordinary.

Immunity 364
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2023 Nobel Prize in Medicine: Karikó, Weissman awarded prize for mRNA research

STAT

Overcoming a lack of broader interest in their work and scientific challenges, Katalin Karikó and Drew Weissman made key discoveries about messenger RNA that enabled scientific teams to start developing the tool into therapies, immunizations, and — as the pandemic spread in 2020 — vaccines targeting the SARS-CoV-2 coronavirus.

Immunity 364
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Covid vaccines averted 3 million deaths in U.S., according to new study

STAT

had relied upon so-called “natural immunity” acquired through infection as the only immunological defense against the virus. times more hospitalizations in the time since December of 2020. But the study results show the toll would have been even worse had the U.S. times more infections, and 3.8

Vaccines 360
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STAT+: ‘I’m just disgusted’: How alleged sexual misconduct stole one student’s passion for academic science

STAT

It was the summer of 2020, and she couldn’t have scripted a better start as a new M.D.-Ph.D. And for a young trainee fascinated with the complex crosstalk between the immune and nervous systems, she’d struck scientific gold — the chance to work in one of the world’s top neuro-immunology labs.

Immunity 246
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STAT+: Medicare would have saved $3.7 billion on Part B drugs if inflationary rebates were around in a recent three-year period

STAT

More specifically, 70 of the 93 top-selling drugs covered by the Medicare Part B program – which are typically pricier medicines that are administered by physicians or in hospitals – between 2018 and 2020 would have been subject to inflationary rebates each year, according to the analysis published in JAMA.

Immunity 246
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The top 5 pharma M&A deals of 2020

pharmaphorum

2020’s M&A activity hasn’t quite reached the heights of last year’s, where two pharma mega-mergers – BMS’ buyout of Celegne and AbbVie’s acquisition of Allergan – accounted for almost 40% of total M&A deal values. Here we take a look at the biggest mergers and acquisitions of 2020 and what they might mean for the companies involved.

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First nasal monoclonal antibody COVID-19 treatment shows potential

European Pharmaceutical Review

Findings from research on the nasal monoclonal antibody “Based on our studies, we expect that Foralumab may work on all variants as it acts on immune effects,” Dr Weiner continued. Foralumab’s immune modulating response In 2020, Moreira researched how Foralumab modulates the immune response to reduce inflammation.

Immunity 145