STAT

OCTOBER 5, 2023

SAN DIEGO — It was spring 2020, and Histogen, a small biotech with big ambitions to regenerate tissues throughout the body and turn a profit in the process, had just gone public. Three years later, Histogen no longer develops therapies.

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Drug Development 323

STAT

OCTOBER 3, 2023

Yesterday’s Nobel wins for Katalin Karikó and Drew Weissman called to mind the humble beginnings of mRNA research — and the fact that Karikó’s scientific career nearly ended before their key discovery, as she explained back in 2020. Read the rest…

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Drug Development 247

STAT

MARCH 29, 2023

In fiscal year 2022, 41% of trial results were submitted to the federal database ClinicalTrials.gov, compared with 34% in the previous year and just 29% in fiscal year 2020. In fact, the vast majority of results — 96%, on average — were eventually submitted to the database.

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Drug Development 246

STAT

OCTOBER 13, 2022

In 2020, its successor, AlphaFold2, achieved near-perfect scores. Then in 2018, a team from DeepMind, a machine-learning company owned by Alphabet, entered the competition for the first time and astonishingly notched about 60 using an artificial intelligence platform called AlphaFold.

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Drug Development 261

pharmaphorum

DECEMBER 21, 2021

However, despite the work still left to be done, there are now a growing number of treatments in the pipeline and 2020 proved to be a remarkable year for orphan drug approvals, with the US FDA approving more orphan designated treatments than non-orphan drugs. The potential to leverage genomic data.

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pharmaphorum

FEBRUARY 10, 2021

A new EU-funded project called In Silico World aims to encourage the use of simulation for drug and medical device development. The post EU-funded project encourages use of simulation in drug development appeared first on.

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Drug Development Packaging Documentation Hospitals 76

STAT

DECEMBER 13, 2024

For more than 30 years, Ionis developed all of its medicines in partnership with large pharmaceutical companies. “The business model was to partner everything,” said CEO Brett Monia, who took the reins in 2020 and implemented the new strategy. This time, it is standing alone.

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Pharmaceutical Companies Pharmaceutical Companies Drug Development 246

Outsourcing Pharma

DECEMBER 16, 2020

Experts from a variety of research and drug development organizations share their thoughts on highlights from 2020, and predict what 2021 might hold.

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Drug Development 92

pharmaphorum

MARCH 21, 2022

Neuroscience is arguably the next great frontier in medicine and 2022 dawned with a wave of exhilarating progress for the neurodegenerative drug development community. The post Welcome to 1st Rare & Genetic Neurodegenerative Drug Development Summit appeared first on.

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Drug Development 52

Drug Patent Watch

DECEMBER 10, 2024

Generic drug development is a complex process that requires a deep understanding of regulatory requirements and guidelines. Regulatory expertise plays a crucial role in ensuring that generic drugs meet the necessary standards for quality, safety, and efficacy. ” Scientific Research Publishing , 2024. ” U.S.

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Drug Development Communication 52

pharmaphorum

DECEMBER 14, 2020

Despite this progress, the vast potential to develop effective treatments that target the human microbiome is still limited by the complex challenges in developing them. The post 5th Microbiome Movement – Drug Development Summit Europe 2021 appeared first on.

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Drug Development 52

Pharma Mirror

NOVEMBER 23, 2021

AI is an emerging technology that is being applied in numerous facets of the pharma sector, ranging from drug development to diagnosis and even patient care. The post AI in Pharma and Biotech Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2020 – 2030 appeared first on Pharma Mirror Magazine.

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Drug Development 52

pharmaphorum

JUNE 30, 2022

Digital technologies are already helping to enable target identification, lead discovery, preclinical development, and clinical development, said Merck. The hope is that by using AI and ML capabilities, the currently unpredictable process of drug development can become much more predictable, and as a result less expensive.

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Research Laboratories Drug Development Compounding 134

Drug Channels

DECEMBER 11, 2020

Read more » Copyright © 2006-2020 Pembroke Consulting, Inc. d/b/a Drug Channels Institute. Drug Channels® is a registered trademark of Pembroke Consulting, Inc. To learn more, visit the Ontada website. This Feed is for personal non-commercial use only.

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Drug Development 52

European Pharmaceutical Review

MARCH 31, 2023

billion in total venture financing raised from 2010 to 2022 for drug development In 2018 alone, the company invested over $400 million in venture financing. This could open doors to greater biopharmaceutical and startup company collaborations in driving innovation for drug development,” Cartic concluded.

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Drug Development 98

Express Pharma

MARCH 30, 2023

billion in total venture financing raised from 2010 to 2022 for drug development. Includes all announced and completed venture financing deals globally related to biopharmaceutical drug development The post HSBC acquisition of SVB UK may result in for new opportunities for biopharma: GlobalData appeared first on Express Pharma.

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Drug Development 95

Pharmaceutical Technology

DECEMBER 6, 2022

HPAPIs may now represent more than 30% of the drug development pipeline. Within that figure, GlobalData estimates that around 60% of pipeline HPAPIs are developed to target oncology. Between 2018 and 2020, 58% of the small molecule API contract manufacturing sites purchased worldwide offered containment.

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Drug Development Dosage Pharmaceutical Manufacturing Communication 52

pharmaphorum

APRIL 28, 2022

OMass Therapeutics has raised an impressive $100 million in a Series B financing that is said to be the largest ever for a UK biotech focusing on small-molecule drug development.

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Drug Development 105

European Pharmaceutical Review

AUGUST 1, 2022

The DDiCT project will be co-led by Bristol Myers Squibb (BMS)’s Disability Advancement Workplace Network (DAWN) and the Global Drug Development Team. The goal is to “ensure all patient groups are reflective of the real-world population and aligned with the epidemiology of the disease studies,” a statement said.

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Drug Development Pharmaceutical Companies Pharmaceutical Companies 122

Express Pharma

APRIL 17, 2024

Biopharmaceutical companies are regaining interest in metabolic dysfunction-associated steatohepatitis (MASH) innovator drug development. MASH innovator drugs witnessed over $2.5 GlobalData’s Pharma Intelligence Center Deals Database reveals that MASH drugs secured over $5.7

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Drug Development Diabetes 95

pharmaphorum

NOVEMBER 2, 2022

With the merger now completed, Norstella becomes a $5 billion group with 1,500 employees across the five business brands with the overarching objective of guiding life sciences companies through the drug development process so patients can get access to therapies more quickly. Photo by Edge2Edge Media on Unsplash.

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Drug Development Communication 101

European Pharmaceutical Review

JANUARY 2, 2024

Pharma pushes for UK medicine scheme revision Drug pricing was considered as the most negative emerging regulatory and macroeconomic trend, impeding growth for the industry, based on GlobalData’s 2019, 2020, 2021, and 2022 industry outlooks.

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Drug Pricing Drug Development 102

European Pharmaceutical Review

OCTOBER 31, 2022

The characterisation resulting from this process is also required to inform the scaleup of drug substance and product, a separate milestone in these initial stages of drug development. Scaling up small molecule drugs manufacturing. Trends in FDA drug approvals over last 2 decades: An observational study.

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Compounding Drug Development Pharmaceutical Companies Pharmaceutical Companies 125

European Pharmaceutical Review

JANUARY 11, 2024

chronic neuropathic pain is at present, mainly managed with antidepressants… antiepileptic drugs… as well as opioids” Neuropathic pain affects over 400 million people worldwide, according to Hoba Therapeutics. He has been responsible for development programmes in multiple indications, spanning all phases of drug development.

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Drug Development Medical Schools 102

pharmaphorum

OCTOBER 31, 2022

Verge is one of a growing number of companies trying to tap into vast data sets to identify and develop patient response markers and hitherto unaddressed drug targets, with the aim of making drug discovery cheaper and more efficient.

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Compounding Drug Development 136

Pharmaceutical Technology

JULY 20, 2022

Gladstone Institutes senior investigator and UCSF Quantitative Biosciences Institute director Nevan Krogan made a detailed map in 2020 displaying which proteins of the virus directly interact with which proteins in infected human cells. But certain elements of these drugs could be adapted for future drug development.”.

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Drug Development 111

European Pharmaceutical Review

APRIL 12, 2023

Historically, the BBB has posed significant challenges to drug development for central nervous system (CNS) diseases by preventing delivery of most therapeutically relevant drug concentrations to the brain. About the license option The option was exercised pursuant to a collaboration between Biogen and Denali announced in 2020.

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Drug Development 102

pharmaphorum

MARCH 24, 2022

GlaxoSmithKline has thrown its financial and drug development weight behind LifeMine Therapeutics, a US startup that aims to find new therapeutics from fungi – widely regarded as an underexplored resource of biologically-active compounds. Image by jggrz from Pixabay .

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pharmaphorum

SEPTEMBER 29, 2020

As of 2018, there were over 1,100 cancer therapies in development, and as of 2020, 362 of them were cell and gene therapies. It enables the companies to work closely together, throughout the continuum of research, development and commercialisation.

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Drug Development Chemotherapy Pharmaceutical Companies Pharmaceutical Companies 132

pharmaphorum

JANUARY 25, 2021

The pandemic has propelled the life science industry toward higher expectations for faster, more responsive and more inclusive drug development. Sponsors may start to appreciate the benefits of allowing industry regulators to pull up a seat at the development table, for example. On the path to better product development.

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Communication Drug Development 125

pharmaphorum

OCTOBER 27, 2020

Sales are expected to rise by a mid-single digit percentage in 2020 as a whole. The company also said that drug development is continuing with “manageable disruptions”, thanks to the use of digital technologies that are helping it to keep clinical trials running.

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Drug Development 98

pharmaphorum

SEPTEMBER 29, 2022

Regulators and health technology assessment (HTA) bodies are increasingly demanding the patient voice play a central role in drug development – making it riskier for developers to ignore the need for engagement than to embrace it. Building relevance. The patient centricity movement has been building momentum in recent years.

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Drug Development Documentation 98

pharmaphorum

APRIL 19, 2021

With her patient engagement leadership and focus on incorporating patient voice throughout the drug development journey, I look forward to working with her.”. Peter Agathangelou, executive director of strategy and innovation at Prime Global, said, “I’m thrilled to welcome Emma!

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Communication Drug Development 59

European Pharmaceutical Review

SEPTEMBER 21, 2023

In this Q&A, Karen Pinachyan, Head of Medical Affairs Europe at CSL Behring summarises key considerations for gene therapy drug development and the ideal approach for alleviating economic strain when advancing these modern treatments. 4,5 What is the key consideration drug developers should apply to gene therapies?

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Drug Development Pharmaceutical Companies Pharmaceutical Companies Diabetes 96

Express Pharma

MAY 22, 2023

The addition of India to this important study will help to accelerate the development of this drug,” said Mickey Mikitani, Co-CEO, Rakuten Medical. ASP-1929 is a conjugation of antibody cetuximab and IRDye 700DX, a light activatable dye, and is Rakuten Medical’s first pipeline drug developed on its Alluminox platform.

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Labelling Drug Development 98

pharmaphorum

DECEMBER 9, 2022

“Many of these patients with metastatic breast cancer in TROPION-PanTumor01 had exhausted most of their available treatment options, having received a striking median of five prior regimens, including a CDK4/6 inhibitor for nearly all patients,” said Cristian Massacesi, who heads up oncology drug development at AZ.

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Chemotherapy Drug Development 98

pharmaphorum

JANUARY 18, 2022

According to Rock Health’s annual digital health funding report, US-based digital health companies enabling life sciences research and development raised $5.8 This is the first time R&D has topped the chart since Rock Health began tracking US digital health funding in 2011, although it nabbed the number two slot in 2018 and 2020.

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Drug Development 91