pharmaphorum

MARCH 19, 2021

In doing so it’s compounded pre-existing pressure with pharma, where schedules are shrinking and policies are often already restrictive enough to build barriers for effective physician engagement. The threat of disease spread and other risk factors from COVID-19 have only compounded this.

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Compounding Pharmaceutical Companies Pharmaceutical Companies Communication 141

European Pharmaceutical Review

JANUARY 29, 2024

The guideline states that compounds “at or above the AET must be reported for toxicological risk assessment.” The researchers evaluated DHS extraction performance and compared it to traditional SHS and SBSE GC–MS methods. The paper highlighted that SHS analysis is currently a supplementary technique for volatile analysis.

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Compounding 98

European Pharmaceutical Review

OCTOBER 31, 2022

Solving this before the clinical stage ensures the viability of compounds…” Addressing bioavailability challenges in the first phases of development is essential to help create the most robust product profile and increase the potential for success as small molecule drugs move to the clinic. amorphous solid dispersions, or ASDs.

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Compounding Drug Development Pharmaceutical Companies Pharmaceutical Companies 125

pharmaphorum

JUNE 30, 2022

AI-designed drug candidates are starting to reach the human testing stage, headed by Exscientia’s DSP-1181 candidate for obsessive-compulsive disorder partnered with Sumitomo Dainippon Pharma, which started a clinical trial in 2020.

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Research Laboratories Drug Development Compounding 134

Pharmaceutical Technology

DECEMBER 10, 2024

The respiratory syncytial virus (RSV) prophylaxis market across the eight major markets (8MM) - comprising the US, the five major European markets (France, Germany, Italy, Spain, and the UK), Japan, and Australia - is forecast to grow from $582m in 2020 to $6.2bn in 2030 at a compound annual growth rate of 26.7%, with the paediatric and adult segments (..)

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Compounding 59

pharmaphorum

MARCH 24, 2022

GlaxoSmithKline has thrown its financial and drug development weight behind LifeMine Therapeutics, a US startup that aims to find new therapeutics from fungi – widely regarded as an underexplored resource of biologically-active compounds. Image by jggrz from Pixabay .

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Compounding Immunity Immunization Drug Development 105

pharmaphorum

NOVEMBER 24, 2020

The combined company will cover a broad swathe of the digital health landscape, bringing together population health software, telehealth services, digital pharmacy delivering compounded and manufactured medicines, and tech enabled behavioural health services for people with mental health and substance abuse issues.

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Packaging Compounding 138

pharmaphorum

MARCH 2, 2022

The term ‘psychedelic treatments’ incorporates a broad spectrum of different compounds, from LSD, psilocybin and DMT, to MDMA, ibogaine and ketamine. The latter compound has already been approved for treatment-resistance depression as the product Spravato (esketamine), after being developed by Janssen. Paving the way to patients.

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Compounding Drug Development 105

Pharmaceutical Technology

NOVEMBER 25, 2022

Additionally, the platform could produce preclinical tumour vaccine candidate compounds with strong immune activity by incorporating algorithmic feedback to streamline activity and efficacy. In September 2020, the company raised funds worth $318.8m Automated experiments will be used to monitor and validate the tumour vaccines.

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Vaccines Immunity Immunization Process Improvement 98

pharmaphorum

OCTOBER 31, 2022

. “We are proud to be not just one of the few AI-driven biotech companies to have made it to the clinical stage, but also one of the first to bring forward a novel clinical compound against a novel target, that was entirely discovered and developed internally on our platform,” said Zhang, who acts as Verge’s chief executive.

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Compounding Drug Development 136

European Pharmaceutical Review

AUGUST 19, 2022

The market was valued at approximately $100 billion in 2020. percent compound annual growth rate (CAGR) of the market include the increasing commercialisation of generics and emerging technologies and small biotechs with limited or no production capabilities driving development in the biopharmaceutical sector. billion by 2026.

Packaging 98

Packaging Compounding 98

Express Pharma

APRIL 18, 2023

billion in 2020 to $29.8 billion in 2030 at a compound annual growth rate (CARG) of 4.6 Ocrevus and Kesimpta were first approved in MS in 2017 and 2020, respectively. The market for multiple sclerosis (MS) disease-modifying therapies (DMT) is set to experience moderate growth across the seven major markets (7MM*) from $18.9

Compounding 98

Compounding 98

European Pharmaceutical Review

OCTOBER 7, 2022

billion by 2030, displaying a compound annual growth rate (CAGR) of 6.0 In the years 2015 and 2020, clinical-stage cancer programmes increased by a considerable 77 percent (1,642 to 2,911), resulting in a quarter of drugs currently in development worldwide being highly potent.

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Dosage Compounding Pharmaceutical Companies Pharmaceutical Companies 98

pharmaphorum

JANUARY 11, 2023

The industry now hopes that feeding the same limited experiential data to AI may help tweak existing drug-like compounds slightly faster than before. Bucking the compound library trend, and the future. The drug candidates we find are vastly different from the compound libraries used by the rest of our industry.”.

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Compounding Drug Development 122

pharmaphorum

NOVEMBER 3, 2021

The report refers to data collected across 350+ global pharma companies between November 2020 through January 2021, and notes a 70% compound average growth rate in the volume of content managed in Veeva Vault PromoMats since 2018.

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Compounding Communication Pharmaceutical Companies Pharmaceutical Companies 98

Pharmaceutical Technology

NOVEMBER 29, 2022

This takeover will bolster the pipeline of Full-Life, offer a second peptide-based discovery platform and utilise the Radio Technology manufacturing and logistics platforms of Focus-X to progress compounds into clinics. The company’s pipeline currently has two lead compounds, which are set to enter clinical trials.

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Compounding 59

pharmaphorum

JULY 13, 2022

Genentech has been looking at the platform since 2020 under the terms of a deal worth up to $1.7 Genentech has been looking at the platform since 2020 under the terms of a deal worth up to $1.7 The time the peptides stay in the body can also be fine-tuned, allowing for precise control of drug exposure, according to the biotech.

Immunity 105

Immunity Immunization Compounding 105

pharmaphorum

FEBRUARY 10, 2022

But the goals of maintaining that momentum and reaping the rewards of 21 st century processes rely on the sector attracting and retaining the staff – a proposition that’s becoming increasingly difficult thanks to a stubborn digital skills gap that is being compounded by the COVID brain drain. Digital skills gap. COVID brain drain.

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Compounding 105

pharmaphorum

JUNE 27, 2022

Tazverik is a first-in-class EZH2a inhibitor that was cleared by the FDA in 2020 as a third-line or later treatment for adults with relapsed or refractory follicular lymphoma (FL) whose tumours have an EZH2 mutation. ” Epizyme’s shares are currently trading at around $0.95, well short of the stock’s 52-week high of $9.86.

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Compounding 110

pharmaphorum

NOVEMBER 15, 2022

Their earlier partnership , signed in 2020, covered small molecule drugs directed at SLC transporters, a class of more than 450 human membrane proteins that are gatekeepers for controlling the movement of metabolites in and out of cells and organs.

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Immunization Immunity Compounding 105

pharmaphorum

JANUARY 13, 2021

The company said this enables the identification of compounds with a dual mechanism of action targeting and killing immunosuppressive cells and tumour cells while indirectly activating other T-effectors. IO102 and IO103 are cancer first-in-class vaccines based on IO Biotech’s proprietary T-win technology platform.

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Vaccines Immunization Immunity Compounding 95

pharmaphorum

AUGUST 11, 2020

A phase 3 trial is expected to begin in 2021 and the company says that the compound could generate peak sales of more than a billion euros globally. At the beginning of this year, KaNDy completed a phase 2b trial of its first-in-class drug NT-814, showing activity against symptoms of the menopause such as hot flashes and night sweats.

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Compounding 98

pharmaphorum

JANUARY 8, 2021

Until 2020, pharma had lagged other industries in its investment in digital marketing. According to the figures compiled in the third quarter of last year, pharma brands were projected to spend around $10 billion in 2020 on digital advertising aimed at all groups including doctors, a compound annual growth rate of more than 13% since 2014.

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Communication Compounding 100

pharmaphorum

JUNE 7, 2022

In a deal signed in 2020, the biotech bought a licence to co-develop and co-market inhibitors of LRRK2 – another target linked to lysosome function – from Denali Therapeutics. It’s not the first time that Biogen has licensed rights to a drug targeting lysosomal function in Parkinson’s disease.

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Compounding 80

Pharmaceutical Technology

SEPTEMBER 15, 2022

The top 13 players reported more than 10% revenue growth, with BioNTech (3,834.4%), Moderna (2,199.1%), Pfizer (95.2%) and Regeneron Pharmaceuticals (89.1%) reporting a more than 80% year-on-year (YoY) revenue growth from 2020 to 2021, according to GlobalData’s Pharma Intelligence Centre Companies Database.

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Vaccines Drug Pricing Biosimilars Documentation 108

Pharmaceutical Technology

JULY 13, 2022

The initial agreement was signed in February 2020 for discovering, developing and marketing new immuno-oncology therapies based on Bicycle’s bicyclic peptide technology. The agreement is exclusive of the compounds in the oncology pipeline of Bicycle, including its immuno-oncology candidates.

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Compounding 59

Express Pharma

JUNE 7, 2024

billion by 2030, at a compound annual growth rate (CAGR) of 4.7 per cent during 2020 -30. According to GlobalData’s forecast on the multiple sclerosis market size, it is expected that sales for MS DMTs will grow to $30.1

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Compounding 80

epicur

DECEMBER 5, 2022

Quick Facts: The veterinary compounding market is expected to increase from US$ 1.1 Bn in 2020 to over US$ 2.7 Quick Facts: The veterinary compounding market is expected to increase from US$ 1.1 Bn in 2020 to over US$ 2.7 Bn by 2031, expanding at a CAGR of around 8.5% Bn by 2031, expanding at a CAGR of around 8.5%

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Compounding Compounding Pharmacies Packaging Hospitals 52

Express Pharma

AUGUST 17, 2023

While Venus Remedies had outlicensed Elores to Cipla in the domestic market in 2020, the worldwide marketing rights for Elores are still vested in the company, which has launched the product in eight countries so far, including Colombia, Dominican Republic, Ethiopia, Guatemala, Myanmar, Oman, Saudi Arabia and Tanzania.

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Compounding 98

pharmaphorum

MAY 11, 2021

Healthcare systems the world over have been facing the same challenges for some time – and the pandemic has only served to compound them. An NHS AI Lab progress report, published last week , said 2020 had been a strong year for AI, with the pressures of COVID-19 helping to highlight many of its potential benefits. The COVID affect.

Compounding 119

Compounding Hospitals 119

RX Note

JANUARY 21, 2023

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

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Compounding Community Pharmacies Clinical Pharmacology Dosage 40

European Pharmaceutical Review

AUGUST 17, 2022

billion by 2030, expanding at a compound annual growth rate (CAGR) of 7.2 For instance, in 2020, Merck’s R&D cost was approximately $2.5 According to a recent report , the global formulation development outsourcing market size should grow to $61.4 percent from its 2022 value of $35.1 billion and Biogen’s approximately $4 billion.

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Compounding Pharmaceutical Companies Pharmaceutical Companies Drug Development 96

Pharmaceutical Technology

FEBRUARY 6, 2023

In March 2020, the findings from the trial were published in the New England Journal of Medicine. We look forward to advancing this new compound as part of combination regimens that could yield a short, simple, safe, and highly effective cure for all forms of TB.”

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Compounding 59

Pharmaceutical Technology

MAY 5, 2023

Since 2020, TFF Pharmaceuticals has entered into multiple CRADAs with various US government agencies that cover a broad range of applications, and today’s announcement with NIEHS is further recognition of thin film freezing’s potential.”

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Compounding 64

European Pharmaceutical Review

DECEMBER 21, 2022

Organic compounds are arguably the foundation of the pharmaceutical industry. All traditional small molecule pharmaceuticals include carbon building blocks” Organic compounds are arguably the foundation of the pharmaceutical industry. Gene Ther 27, 537–544 (2020). Science 369, eabc3183 (2020).

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Compounding Pharmaceutical Manufacturing Pharmaceutical Companies Pharmaceutical Companies 97

European Pharmaceutical Review

FEBRUARY 28, 2023

2020 [cited 2023Jan]. 2020; 24(12): 2915-2926. 2020; 22(4): 89. EMA/409815/2020 Rev.13. Pathways for N-Nitroso Compound Formation: Secondary Amines and Beyond. 2020; 24(9): 1558–1585. 2020; 116: 104749. Stakeholder Forum November 19, 2020. Available from: [link] 4. J Pharm Sci. J Pharm Sci.

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Compounding 98

pharmaphorum

FEBRUARY 2, 2022

ViiV claimed the latter compound infringes its patents for dolutegravir and other compounds based on the drug’s chemical scaffold. Gilead acquired the drug as part of its $21 billion takeover of Immunomedics in 2020. Gilead now expects product sales in 2022 will be between $23.8 billion and $24.3

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Compounding 72