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U.S. drug overdose deaths on pace to fall below 100,000 this year 

STAT

drug overdose deaths are plummeting, putting the country on pace for its first year with fewer than 100,000 overdose deaths since 2020 — a powerful, if bleak, symbolic milestone.

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Opinion: Pediatricians and parents on the brink: This is their March 2020

STAT

In March 2020, as the Covid-19 pandemic swept across the United States, the nation’s pediatric providers and pediatric units immediately pitched in to treat adults sickened by this then-mysterious and deadly disease.

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STAT+: The CRISPR companies are not OK

STAT

No less an authority than a Nobel Prize committee announced, in 2020, that CRISPR “may make the dream of curing inherited diseases come true.”   The gene editing tool, wrested out of bacteria 13 years ago by a fractious group of biochemists, was supposed to change medicine.

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STAT+: Pfizer to pay $60 million to settle claims that Biohaven paid kickbacks to doctors

STAT

The authorities alleged that, from March 2020 through September 2022, Biohaven improperly paid doctors speaking fees and for meals at “high end” restaurants in order to persuade them to prescribe Nurtec ODT, the centerpiece of the $11.6 Department of Justice. billion acquisition.

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STAT+: Sutter Health settles sweeping antitrust case, narrowly avoiding trial

STAT

based Sutter want to be repaid for the money they spent on health insurance from 2011 through 2020.   Terms of the settlement were not immediately released on Monday, but it’s likely sizable given the scope of the case. The individuals and businesses suing Sacramento, Calif.-based Continue to STAT+ to read the full story…

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Opinion: Gene therapy trials should emphasize transparency, not secrecy

STAT

In 2020 and 2021, a clinical trial of a GT using yet a different viral vector and carrying a different genetic cargo resulted in the deaths of four boys soon after administration. He had received a similar viral vector via a different route of administration, carrying a different genetic cargo. Read the rest…

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STAT+: Why Orexo is abandoning a digital therapeutic for depression

STAT

The companies have worked together on Deprexis in the United States since 2020 and have deals for two other apps, including Modia, an app that provides psychosocial support to people being treated for opioid addiction. Orexo announced this week that it will no longer license the product, called Deprexis, from German manufacturer GAIA.