Pharmacy Joe

SEPTEMBER 23, 2021

In this episode, I’ll discuss a possible syndrome that might herald vaccine-induced immune thrombotic thrombocytopenia. Episode 646: Does vaccine-induced immune thrombotic thrombocytopenia have a “pre-VITT syndrome” ? 4 of the patients experienced thrombosis and 7 did not. appeared first on Pharmacy Joe.

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Immunity Immunization Vaccines Inpatient 40

NY Times

DECEMBER 8, 2021

The antibody drug, Evusheld, was found to be strongly effective in preventing Covid in a clinical trial that enrolled mostly those at high risk.

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Immunity Immunization 95

NY Times

APRIL 15, 2021

Many cannot produce enough infection-fighting cells to fend off the coronavirus. But researchers are testing one therapy that may help: monoclonal antibodies.

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Immunity Immunization Vaccines 98

NY Times

FEBRUARY 9, 2022

It’s not clear whether three doses of the Pfizer-BioNTech vaccine will adequately protect young children. But the F.D.A. may authorize the first two doses anyway.

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European Pharmaceutical Review

AUGUST 10, 2022

The deal includes MiroBio’s proprietary I-ReSToRE ( RE ceptor S election and T argeting t o R einstate immune E quilibrium) discovery platform and its entire portfolio of immune inhibitory receptor agonists. MB272 targets T, B and dendritic cells to inhibit or blunt activation and suppress an inflammatory immune response. . “We

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Immunization Immunity 98

NY Times

MAY 11, 2022

Antibody levels rose in the children who received it, suggesting the vaccine protects against infection. But the data were gathered before the arrival of Omicron.

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Vaccines Immunity Immunization 62

Express Pharma

OCTOBER 16, 2024

Messenger ribonucleic acid (mRNA)-based innovator pharmaceuticals saw a staggering 800 per cent increase in licensing agreement deal values from 2019 to 2024YTD, driven by the remarkable success of mRNA vaccines during the COVID-19 pandemic. Bristol Myers Squibb formed a multi-year, $1.87

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Vaccines Immunity Immunization Diabetes 92

European Pharmaceutical Review

DECEMBER 12, 2023

He discusses why NK cell therapy’s ability to generate ‘synthetic immunity’ in the body means this modality holds potential as an anti-cancer treatment. We specialise in the development of new cutting-edge immunotherapies , based on the use of therapeutic antibodies capable of activating the immune system to fight cancer.

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Immunity Immunization Chemotherapy Pharmaceutical Companies 124

NY Times

APRIL 14, 2022

Pfizer and BioNTech will soon ask the Food and Drug Administration for emergency authorization of Covid booster doses for that age group, the companies said.

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Immunity Immunization Vaccines 55

NY Times

JANUARY 27, 2021

Spain has suspended vaccinations in Madrid because of a shortfall of doses, as the European Union locks horns with the drugmaker AstraZeneca over vaccine delivery cuts.

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Vaccines Immunity Immunization 67

European Pharmaceutical Review

MAY 17, 2023

The viral therapy “aims to awaken the patient’s immune system and trigger a healing from within,” Dr Fueyo commented. After injection, patients that respond well develop inflammation inside the tumour, triggering an immune response that first kills the virus.” This makes it difficult to treat the cancer with immunotherapy.

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Immunity Immunization Chemotherapy 98

European Pharmaceutical Review

AUGUST 2, 2023

This is an additional ingredient designed to trigger a stronger immune response. The vaccine demonstrated a strong immune response in the trial. In a clinical trial, this vaccine was shown to faciliate a strong immune response against the Omicron BA.1 1 variant, in addition to the original 2020 strain.

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Vaccines Immunity Immunization 98

NY Times

FEBRUARY 28, 2021

The company’s coming trials will also involve pregnant women and people whose immune systems are compromised.

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Immunization Immunity Vaccines 144

European Pharmaceutical Review

JULY 13, 2023

The field of immunotherapy is constantly evolving with the ultimate goal to develop new treatments that help the body’s immune system fight cancer. Immune cells, such as T cells and natural killer (NK) cells, have the inherent ability to combat diseases, including cancer, but are often inhibited by the body’s own suppressive mechanisms.

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pharmaphorum

AUGUST 5, 2022

MiroBio was formed in 2019 to develop checkpoint agonist antibodies for autoimmune and inflammatory disorders that can be used to apply the “natural brakes” of the immune system. 7 integrin, with three candidates in early-stage clinical development.

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Immunity Immunization Drug Development 100

NY Times

MARCH 23, 2022

The company said the vaccine produced a strong immune response in children younger than 6, but proved only about 40 percent effective in preventing symptomatic Covid-19.

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Vaccines Immunization Immunity 94

NY Times

MARCH 29, 2022

Those 12 and older with certain immune deficiencies are also eligible. People in the age group can get the additional shot at least four months after their first booster.

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Immunization Immunity Vaccines 87

European Pharmaceutical Review

MARCH 19, 2024

This pathway works in the innate immune system to sense cytosolic DNA by triggering a STING-dependent inflammatory response. In September 2019, IFM Due entered into an option and collaboration agreement with Novartis, who agreed to finance IFM Due’s research and development costs for the cGAS-STING programme.

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Immunity Immunization 105

pharmaphorum

JULY 6, 2021

While these types of tests are important, they don’t tell the whole story, as they can’t provide information on whether an individual has built an immune response to COVID-19, either through vaccination or through a previous infection. This is where antibody tests come in. ” . . The Importance of Antibody Certificates.

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Immunization Immunity Vaccines 111

NY Times

DECEMBER 18, 2020

The Food and Drug Administration authorized a second coronavirus vaccine for emergency use, clearing the way for millions more Americans to be immunized next week.

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NY Times

DECEMBER 30, 2021

Regulators will also allow even younger children with immune deficiencies to get an extra shot.

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Immunization Immunity Vaccines 98

pharmaphorum

JANUARY 10, 2023

Since then, the two partners have developed multiple AI-based applications including a platform for selecting neoantigens for use in individualised cancer vaccines and an early warning system for high risk SARS-CoV-2 variants based on how well they can evade the immune system and their transmissibility.

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Immunity Immunization Vaccines 116

Pharmaceutical Technology

APRIL 12, 2023

The latest shipment is based on an exclusive licence agreement signed in 2019 between Pharming and Novartis. Both genes are important for the body’s development and for the functioning of immune cells. Under its terms, Pharming has paid a $10m milestone payment to Novartis for the first commercial sale of Joenja.

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Immunity Immunization 59

pharmaphorum

JUNE 15, 2022

Cytokines have long been investigated for their potential as cancer treatments – selectively stimulate tumour-fighting immune cells – with varying levels of success. The company came to Boehringer’s attention in 2019, when it took part in the drugmaker’s BI Innovation Prize competition.

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Immunity Immunization Vaccines 98

Express Pharma

FEBRUARY 22, 2024

Takeda entered into multiple cell therapy collaborations for the development of CAR-T therapies with organisations like Memorial Sloan Kettering Cancer Center (MSK), Noile-Immune Biotech, and Crescendo Biologics in 2019 to advance the company’s novel immuno-oncology portfolio.

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Immunity Immunization 99

Express Pharma

JULY 19, 2023

million children missed out on one or more vaccines delivered through routine immunization services, compared to 24.4 million children who missed out in 2019 before pandemic-related disruptions, underscoring the need for ongoing catch-up, recovery and system strengthening efforts. million children in 2019.

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pharmaphorum

JUNE 16, 2022

The result isn’t a big surprise – Roche terminated two phase 3 trials of crenezumab in people with prodromal to mild sporadic Alzheimer’s in early 2019 after interim analyses found it would be futile to continue – but is another blow to the amyloid hypothesis.

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Immunity Immunization 111

European Pharmaceutical Review

SEPTEMBER 22, 2023

The vaccination of patients with AN1792 led to the activation of their immune systems, which started producing endogenous anti-Abeta antibodies. Therefore, active immunotherapy to trigger the immune system to produce sustained levels of endogenous antibodies has now become far more attractive.

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Immunity Immunization Vaccines Communication 97

Pharmaceutical Technology

MAY 25, 2023

The results from a trial, published in The New England Journal of Medicine , found the vaccine was associated with a strong immune response and good safety profile. The response was more powerful than that generated by MenACWY-D – a licensed quadrivalent meningococcal vaccine marketed by GSK.

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pharmaphorum

JUNE 3, 2021

Genmab has enlisted the help of Bolt Biotherapeutics to develop a new class of immune-boosting antibody conjugates for cancer in a deal that could be worth up to $880 million. “Creating bispecific ISACs turbo-charged with potent immune stimulants is a novel concept that has tremendous potential for patients,” he added.

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Immunization Immunity 52

pharmaphorum

JANUARY 18, 2021

Quadri, formerly Merck’s head of medical and scientific affairs, immune oncology, has been charged with one count of theft of trade secrets and one count of unauthorised transmission of trade secrets, some relating to the multi-billion dollar cancer immunotherapy Keytruda (pembrolizumab).

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Documentation Immunity Immunization Pharmaceutical Companies 87

pharmaphorum

APRIL 28, 2021

Between just February and May 2020, submissions to Elsevier’s journals alone went up by 58% compared to the same period in 2019. “Text mining was also able to highlight new insights into the mechanisms of pancreatic cancer’s immune evasion, which refers to cancer cells’ ability to evade an immune response” .

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Pharmaceutical Business Review

JULY 21, 2023

It is shown that by using a further adjuvant, two doses administered over 14 days demonstrate protective levels of immune response, and this can be particularly significant in response to a public health emergency involving anthrax. In 2019, the US government commenced procuring this product for national preparedness efforts.

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European Pharmaceutical Review

JANUARY 26, 2024

It is a key component of human vaccines for shingles, malaria, coronavirus disease 2019 and others under development.” Bioengineering vaccine adjuvants The paper explained: “QS-21 is a potent vaccine adjuvant currently sourced by extraction from the Chilean soapbark tree. Martin et al. Martin et al.

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Pharmaceutical Business Review

JULY 31, 2024

Since its inception in 2019, the platform generated several promising pre-clinical programmes in oncology and beyond. These candidates show promise for treating TKI-resistant tumours, immune checkpoint inhibitor-resistant tumours, and other disease targets, indicating a broad potential impact in oncology and other therapeutic domains.

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Immunity Immunization 59

European Pharmaceutical Review

JULY 12, 2022

By binding to both CD19, an antigen expressed on B-cells, and to the CD3 receptor on T-cells, TNB-486 activates and recruits T-cells to CD19-expressing tumours where they can elicit an immune response. “By The post AstraZeneca to acquire TeneoTwo and its blood-cancer therapeutic appeared first on European Pharmaceutical Review.

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Immunity Immunization Chemotherapy 98

Pharmaceutical Technology

SEPTEMBER 21, 2022

In January 2019, the companies entered a collaboration agreement under which Pfizer agreed to use CytoReason’s technology for developing cell-based models of the immune system. With the latest development, the partnership would be worth up to $110m over the next five years.

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Immunity Immunization Drug Development 52