ALiEM - Pharm Pearls

NOVEMBER 27, 2023

A 24-year-old G1P0010 female with a PMHx of ovarian cyst (unknown laterality) and emergency contraceptive use 3 months prior presented with sudden onset abdominal pain (upper > lower) that awoke her from sleep four hours prior to presentation with associated nausea and mild lower back pain. References Moon, Y.H., Theofanakis, C.P.,

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ALiEM - Pharm Pearls

DECEMBER 4, 2023

A 49-year-old male presented to the emergency department of an academic hospital with the chief concern of penile pain. The patient was recently admitted to the hospital eight days prior to presentation for purulent urethral discharge where he received a course of topical antibiotics and was discharged. 2018 May 9;13:158-163.

Hospitals 152

Hospitals Medical Schools Diabetes 152

ALiEM - Pharm Pearls

MARCH 6, 2023

A 48-year-old female with a past medical history of opioid use disorder on suboxone presents with abdominal pain for one day. Left atrial myxoma presenting as an embolic shower: a case report and review of literature. The patient developed sharp diffuse upper abdominal pain the evening prior to arrival that resolved. Gaudreault, V.,

Hospitals 189

Hospitals 189

ALiEM - Pharm Pearls

JUNE 15, 2023

Lily of the valley poisoning is important to recognize because it presents as digitalis toxicity [3]. 2, 7] Gastrointestinal decontamination with activated charcoal may be considered in patients who present early after ingestion (up to 2-4 hours). Digoxin specific Fab fragments are recommended if significant toxicity is present.

Hospitals 246

Hospitals 246

Express Pharma

OCTOBER 23, 2024

Key speakers from Uhlmann included Sumeet Arora, Matthias Kaiser, and Varun Sethumadhavan were also present. ” Uhlmann began localising format parts in 2018-19 to reduce lead times and costs associated with imports.

Packaging 104

Packaging 104

RX Note

AUGUST 19, 2024

When infection is present, the most common bacterium is Escherichia coli , and the source is often the gastrointestinal tract. to prevent recurrent urinary tract infections in females, 2018 Summary If urinary tract infection symptoms persist, referral to a physician for empiric antibiotic therapy may be necessary.

Community Pharmacies 40

Community Pharmacies 40

ALiEM - Pharm Pearls

DECEMBER 8, 2023

A 45-year-old male status-post right nephrectomy secondary to a renal mass presented to the emergency department with right-sided flank pain. 2018 Apr;22(2):353-361. Epub 2018 Jan 27. Over the course of the past several days, the mass had become larger and more painful. Treasure Island (FL): StatPearls Publishing; 2023 Jan–.

Diabetes 152

Diabetes 152

ALiEM - Pharm Pearls

MAY 13, 2024

Early cellulitis may present as skin thickening (Figure 4). Epidermoid cyst (image courtesy of The Pocus Atlas and Dr. Robert Jones ) Abnormal: Foreign Body Soft tissue foreign bodies are a common pediatric presentation and can be easily identified on ultrasound. 2018 Jan;54(1):96-101. 2018 Nov;55(5):693-701. Lam et al.,

Medical Schools 161

Medical Schools 161

ALiEM - Pharm Pearls

MARCH 7, 2024

Severity Grading Hydronephrosis severity grading begins with dilation at the renal pelvis (grade 1 or pelviectasis), which can be present in normal individuals who have not urinated in some time. Hydronephrosis may be secondary to various obstructive etiologies such as nephrolithiasis, masses, or anatomical anomalies. Dessie et al.,

Labelling 177

Labelling Communication 177

ALiEM - Pharm Pearls

SEPTEMBER 25, 2023

66 year-old-male with a history of type 2 diabetes and hypertension presented as a transfer for rapid progression of lower extremity pain, swelling, and blue-purple discoloration of the entire limb with concern for a possible necrotizing infection. 2018 Sep 25;11(3):355-357. He had no known thromboembolic risk factors. Ann Vasc Dis.

Medical Schools 152

Medical Schools Diabetes 152

pharmaphorum

MARCH 25, 2021

However, COVID-19 is widely thought to have significantly impacted every aspect of cancer care – from diagnosis and patients’ willingness to present for treatment through to service delivery and follow-up care. Cancer incidence has been rising in the UK but deaths have been declining and survival rates increasing until the pandemic.

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Pharma Marketing Network

MAY 15, 2023

One of the biggest opportunities presented by big data in the pharmaceutical industry is the ability to gain insights into patient needs and preferences. Another opportunity presented by big data in pharmaceutical marketing is the ability to improve the efficiency of clinical trials. 8 (2018) 2. References 1. 1 (2016) 3.

Pharmaceutical Companies 59

Pharmaceutical Companies Pharmaceutical Companies Drug Development 59

ALiEM - Pharm Pearls

NOVEMBER 1, 2023

What clinical presentation and medication is associated with this urinary discoloration? 22 Aug 2018. 2000 Jun;59(6):1233-50. PMID: 10882160 The meaning behind the color of urine. The Meaning Behind the Color of Urine – Urology Care Foundation. American Urological Society. appeared first on ALiEM.

Clinical Pharmacology 161

Clinical Pharmacology Dosage Compounding 161

pharmaphorum

JUNE 1, 2022

Cambridge, Massachusetts-based GO – led by CEO Constantine Theodoropulos – was formed to develop a cancer immunotherapy platform based on targeting O-glycoproteins, a group of molecules that seem to present differently on cancer cells compared to normal cells.

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European Pharmaceutical Review

AUGUST 4, 2023

There are at present, nine US Food and Drug Administration (FDA)-approved agents, GlobalData stated. Patent litigation for adalimumab resolved in the US … Mylan’s Hulio (adalimumab), launched in Europe in 2018, is currently undergoing interchangeability studies. Worldwide sales for Humira peaked at $21.2

Biosimilars 97

Biosimilars 97

Pharma Marketing Network

MARCH 23, 2023

One of the biggest opportunities presented by big data in the pharmaceutical industry is the ability to gain insights into patient needs and preferences. Another opportunity presented by big data in pharmaceutical marketing is the ability to improve the efficiency of clinical trials. 8 (2018) 2. References 1. 1 (2016) 3.

Pharmaceutical Companies 52

Pharmaceutical Companies Pharmaceutical Companies Drug Development 52

European Pharmaceutical Review

FEBRUARY 10, 2023

Kenji Yasukawa, present Representative Director, President and CEO of Astellas, will be Representative Director, Chairman of the Board following the change. The company has worked on CSP2021 since fiscal year 2018, when Kenji Yasukawa was appointed as President and CEO.

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Pharmaceutical Technology

JUNE 21, 2023

With an estimated enrollment of 182 patients undergoing abdominoplasty, the company will present data comparing its transdermal system with a placebo in Q3 of 2023. Opioid-based medication remains the go-to option for pain management. However, the opioid epidemic in the US has catalysed a shift in focus to alternatives.

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80

Express Pharma

NOVEMBER 30, 2024

The country’s health metrics, such as the growing burden of non-communicable diseases, rising life expectancy, malnutrition, and air pollution, present a further scope for innovations in life sciences to strengthen healthcare delivery estimated to reach $60 billion by FY 2028 (1).

Communication 105

Communication 105

Express Pharma

JUNE 28, 2024

A joint IPA-McKinsey presentation pointed out that as of March 2024, as part of the quality drive in the past year, around 64 pharmacos licenses, 53 licenses were suspended, and 17 drug testing laboratories shut down for non-compliance with GMP or continued lapses.

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European Pharmaceutical Review

JANUARY 24, 2023

The Phase III trial for refractory metastatic CRC In September 2022, results of FRESCO-2, the Phase III trial of fruquintinib in refractory metastatic CRC were presented at the European Society for Medical Oncology Congress. It was launched commercially in China in November 2018 under the brand name ELUNATE ®.

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Pharmaceutical Technology

MAY 30, 2023

Valneva chief medical officer Dr Juan Carlos Jaramillo stated: “Chikungunya represents a major threat for people travelling to or living in areas where chikungunya virus and the mosquitos that transmit it are present, including popular destinations for US and Canadian travellers.

Vaccines 52

Vaccines 52

European Pharmaceutical Review

APRIL 24, 2023

New European analysis of the CAR T-cell therapy showing these results were presented at the 2023 Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT). This first dataset was compared to data from 1,115 European patients who underwent leukapheresis between 6 September 2018 and 5 September 2020.

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Pharmaceutical Business Review

MARCH 30, 2023

At present, the shares of Sensidose are listed on Spotlight Stock Market in Sweden. Sensidose has carried out sales in Sweden since the end of 2016, as well as in Norway and Denmark since 2018. The independent bid committee of Sensidose has recommended the cash offer.

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RX Note

APRIL 2, 2024

Pharmacologic Management Pharmacologic therapy should only be used during periods when symptoms are present since none of the interventions have been shown to be disease-modifying. For mild to moderate osteoarthritis, consider paracetamol or topical NSAIDs.

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European Pharmaceutical Review

JULY 12, 2022

Microbes developing resistance to disinfectants is a major emerging problem in pharmaceutical manufacturing cleanrooms and, if left unchecked, could present a threat to drug quality and, therefore, human health. However, none of the organism showed growth at MIC concentrations, suggesting resistance was not present in the isolated strains.

Pharmaceutical Manufacturing 111

Pharmaceutical Manufacturing Pharmaceutical Companies Pharmaceutical Companies 111

Pharmaceutical Technology

JULY 4, 2022

The mAb is presently in the Phase II development stage. The companies signed a partnership, option and license agreement in May 2018 under which Brii Bio gained the option for the acquisition of exclusive rights to some programmes of Vir in Greater China.

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111

RX Note

FEBRUARY 8, 2024

More than 800 case studies are presented to stimulate the reader to integrate and apply therapeutic principles in the context of specific clinical situations, cultivating the critical thinking skills essential to optimal patient outcomes. Key information in pharmacy is presented in an easy-to-understand format.

Compounding 52

Compounding Hospitals Diabetes 52

European Pharmaceutical Review

MAY 3, 2023

At present, over 140 digital technologies have and are being developed by over 100 industry stakeholders to enable the biologic manufacturing. Collaboration in the digital biomanufacturing market The research highlighted that over 75 strategic partnerships related to digital biomanufacturing have been forged since 2018.

Compounding 105

Compounding 105

European Pharmaceutical Review

FEBRUARY 23, 2024

Prior to his present role, Robert served as vice chairman and president at AbbVie. Robert’s other roles at AbbVie include: President and Chief Operating Officer in 2023 Vice Chairman and President in 2022 Vice Chairman of finance and commercial operations in 2021 Chief Financial Officer in 2018.

Hospitals 97

Hospitals 97

European Pharmaceutical Review

FEBRUARY 10, 2023

The CGT Catapult established its 7,700m 2 Medicines and Healthcare products Regulatory Agency (MHRA) licensed Manufacturing Innovation Centre (MIC) in Stevenage in 2018. The facility houses 12 segregated independent Good Manufacturing Practice (GMP) cleanroom modules and offers international connectivity and supply chain links.

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pharmaphorum

JUNE 6, 2022

Eversana now will incorporate a suite of sales rep training components developed by Limitless Minds into its life sciences learning and performance platform, including keynote speaker presentations, mindset assessment and training, mental conditioning webinars, and ongoing performance coaching.

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pharmaphorum

NOVEMBER 3, 2021

Pharma companies are producing and distributing more digital content than ever due to the pandemic, meaning the content presented needs to stand out in the crowded digital space to garner attention. Content metrics is the collection of data related to an industry or a company’s content.

Compounding 98

Compounding Communication Pharmaceutical Companies Pharmaceutical Companies 98

RX Note

JULY 15, 2023

Symptoms The lesion may be present at birth, or appear within the first month of life. It may initially present as a faint pink or red patch on the skin, often mistaken for a scratch. Introduction Infantile haemangioma (also known as strawberry naevus) is a common benign vascular tumour that affects up to 10% of neonates.

Hospitals 52

Hospitals 52

pharmaphorum

APRIL 10, 2017

Indeed, QuintilesIMS forecasts that, between 2013 and 2018, 94% of list price value growth will be in specialty medicines – with orphan drugs at the forefront of this trend.

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Pharmacy Joe

OCTOBER 27, 2021

Starting in 2018, the journal has run articles and editorials that have highlighted potential issues with chlorhexidine oral care in ventilated ICU patients. However, this article is presented in a neutral and fair manner – despite the outcome not matching the original hypothesis of the investigators.

Inpatient 40

Inpatient 40

pharmaphorum

AUGUST 18, 2022

Whereas I see now, hopefully moving forward, those topics will still be present, obviously, but the focus is going to be much more on how they are used by patients –how are they integrated into daily life for the people who really need to use these in a real-world setting?”.

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