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FDA approves Novo Nordisk’s Wegovy for cardiovascular risk reduction

Pharmaceutical Business Review

This label expansion follows a supplemental New Drug Application (sNDA) submitted by the company. The study, which was initiated in 2018, enrolled 17,604 adults across 41 countries to assess the efficacy of semaglutide 2.4mg in comparison to placebo as an adjunct to standard of care for MACE prevention.

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Blood Sugar, Hashimoto’s, Ozempic, Metformin and Berberine

The Thyroid Pharmacist

Ozempic is a GLP-1 agonist and is actually marketed as a diabetes drug, but many physicians are prescribing it for weight loss (off label-use). Ozempic’s label warns, “In studies with rodents, Ozempic® and medicines that work like Ozempic® caused thyroid tumors, including thyroid cancer. 2018 Aug;20(8):1951-1956. In: StatPearls.