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First AI-generated small molecule drug enters Phase II trial

European Pharmaceutical Review

Achievement of the first dose in human patients is a “milestone” for AI-driven drug discovery and drug development , stated Feng Ren, PhD, co-CEO and Chief Scientific Officer of Insilico Medicine. In February 2021, the small molecule drug INS018_055 started a first-in-human study for IPF in November 2021.

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Paradigm Shift in Drug Development: Analytical Quality by Design and Analytical Procedure Life Cycle

Quality Matters

Paradigm Shift in Drug Development: Analytical Quality by Design and Analytical Procedure Life Cycle In today’s pharmaceutical manufacturing environment, companies face increasing pressure to respond to changing demands across the global medicines supply chain while still maintaining the quality of their drug products.

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2022 spells change for EU pharmaceutical legislation

European Pharmaceutical Review

The review was impacted by Brexit and the COVID-19 pandemic, which compounded existing issues surrounding high drug pricing and patient access that had been brewing since 2016 and highlighted several shortcomings in the EU’s pharmaceutical system. pocket expenses account for only seven percent of the overall cost of developing drugs.

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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. About the author. 5): V38-V49.

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Patents: a necessary evil?

European Pharmaceutical Review

This is the practice of modifying the product, ie, changing the dosing interval from three times daily (tid) to once daily (od) using controlled release dosage forms immediately prior to generic entry into the market – but equally it could be argued also improving patient compliance. 26 April, 2016. References. 2022;12(7):3049-3062.