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Smartphone-powered trial backs J&J’s Invokana for heart failure

pharmaphorum

It enrolled patients with and without type 2 diabetes and heart failure, to see whether treatment with Invokana (canagliflozin) can improve their symptoms, function and quality of life compared to placebo. billion in 2016 before the product was linked to an increased risk of lower limb amputation.

Diabetes 105
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SGLT-2 Inhibitors

RX Note

Introduction The treatment approach for type 2 diabetes mellitus has undergo a shift from the traditional glucose-centric approach to the new cardiorenal-metabolic approach. This change emphasizes a comprehensive approach for reducing the risk of diabetes-related complications.

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Is Stevia Good or Bad for Hashimoto’s Disease?

The Thyroid Pharmacist

I knew he was right — sugar can contribute to a yeast overgrowth, lowered immunity, blood sugar issues, weight gain, diabetes, and a whole host of health problems (1-3) — but I was a sugar addict, and it was devastating to think that I would have to let go of this old friend and not have any sweetness in my life.

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Merck makes another bioelectronics play, partnering with Innervia

pharmaphorum

Bioelectronic medicine focuses on the fact that every organ in our bodies is innervated with neural networks, so electrical interfacing with peripheral nerves can be a potential pathway for diagnosing or treating diseases such as diabetes.

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Moving towards oral delivery of biologics

European Pharmaceutical Review

Of the 175 new drugs approved by the US Food and Drug Administration (FDA) between 2016 and 2019, most were biologics. Results from the first open-label, single-centre study of RT-101,6 which was conducted in Australia, were reported at the start of 2020. Diabetes Therapy. The Business Research Company. 2019;10(2):437–49.

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Educating for Empathy: Patient versus Provider Perspectives

Pulses

Patient is a 19-year old female presenting to the ER with signs and symptoms of DKA (diabetic ketoacidosis) as evidenced by mental disorientation, random blood glucose of 452, persistent nausea and vomiting, and urinalysis positive for ketones. 2016 Aug 17 [cited 2020 Oct 9];31(5):437-447. A lab panel is pending. So what can be done?

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Tackling multimorbidity through collaboration

pharmaphorum

In a recent analysis of data from 2016 at the Queen Elizabeth Hospital Birmingham, 75% of unplanned admissions, which account for almost 30,000 admissions per year, were for older adults. Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. The hallmarks of aging. EBioMedicine.