ALiEM - Pharm Pearls

FEBRUARY 27, 2023

Septic arthritis of the facet joints is a rarity, particularly in pediatrics and in the cervical spine; case reports largely describe a lumbar location in elderly adults with predisposing comorbidities (intravenous drug use, diabetes, immunosuppression) for spontaneous infection. doi: 10.1136/bcr-2016-218510. BMJ Case Rep.

Diabetes 161

Diabetes 161

ALiEM - Pharm Pearls

SEPTEMBER 9, 2024

A 61-year-old female with a past medical history of hypertension, hyperlipidemia, type 2 diabetes, and normal pressure hydrocephalus s/p VP shunt (last revision nine months ago) presented to the Emergency Department (ED) for evaluation after noticing a “string” coming out of her anus today. 2016 Dec 28;7(Suppl 44):S1150-S1153.

Diabetes 152

Diabetes Hospitals 152

European Pharmaceutical Review

JUNE 26, 2024

[the new facility will double] the combined square footage of all three of [Novo Nordisk]’s existing facilities in North Carolina” Overall, the expansion will support Novo Nordisk’s ability to produce injectable treatments for obesity and other chronic diseases such as diabetes.

Diabetes 104

Diabetes Pharmaceutical Companies Pharmaceutical Companies 104

pharmaphorum

JUNE 1, 2021

Novo Nordisk – which is already active in stem cell therapies with a candidate in early development for type 1 diabetes – is on the hook for up to $598 million in total licensing and milestone payments plus royalties on sales if HS-001 reaches the market.

Immunity 138

Immunity Immunization Diabetes 138

The Thyroid Pharmacist

SEPTEMBER 2, 2022

A review paper published in 2010 that discussed the relationship between thyroid dysfunction and metabolic disorders, highlighted the fact that patients with diabetes were up to three times more likely to develop a thyroid disorder. (7). Hypoglycemia is an early risk factor for developing diabetes. Type 2 Diabetes.

Diabetes 98

Diabetes Health and Personal Care Stores Immunity Immunization 98

RX Note

JUNE 10, 2023

Introduction The treatment approach for type 2 diabetes mellitus has undergo a shift from the traditional glucose-centric approach to the new cardiorenal-metabolic approach. This change emphasizes a comprehensive approach for reducing the risk of diabetes-related complications.

Diabetes 52

Diabetes Labelling Hospitals 52

The Thyroid Pharmacist

JUNE 16, 2023

Thyroid Function Although there is a lot of data on black seed oil, there had been little study in the Hashimoto’s population, until a 2016 Iranian study looked at the therapeutic use of black seed oil in people with Hashimoto’s thyroiditis. [7] A 2016 study found that TQ was able to eradicate 96.8 2016; 16: 471.

Diabetes 116

Diabetes Dosage Compounding Immunity 116

PharmD Live

DECEMBER 21, 2021

Among the approved medications are: Gemtesa (vibegron) for Overactive Bladder (OAB); Verquvo (vericiguat) Heart Failure with reduced EF; Kerendia (finerenone) for prevention of kidney disease and cardiac complications in type 2 diabetes patients. Diabetes mellitus has been a known condition for centuries. All rights reserved.

Diabetes 52

Diabetes Hospitals 52

The Thyroid Pharmacist

OCTOBER 7, 2022

I knew he was right — sugar can contribute to a yeast overgrowth, lowered immunity, blood sugar issues, weight gain, diabetes, and a whole host of health problems (1-3) — but I was a sugar addict, and it was devastating to think that I would have to let go of this old friend and not have any sweetness in my life.

Diabetes 98

Diabetes Immunity Immunization Labelling 98

pharmaphorum

JUNE 28, 2021

They are costly in terms of economic burden and quality of life, especially among older patient populations, and are closely linked to other chronic conditions such as cardiovascular disease and diabetes. From 2016 to 2019, he was the chief business officer at miRagen therapeutics.

Diabetes 105

Diabetes Drug Development 105

PharmD Live

MAY 13, 2024

However, aging also brings about physiological and pathological changes that increase the risk of developing multiple chronic diseases, such as cardiovascular disease, stroke, and diabetes. Major polypharmacy: more than 5 medications.

Long-Term Care Facilities 105

Long-Term Care Facilities Diabetes Nursing Homes Prescription Filling 105

RX Note

JUNE 30, 2023

diabetes mellitus ) and medications. Tissue removal - Any non-viable slough or necrotic tissue must be removed if the wound is to heal. Infection or inflammation - Host resistance is lowered by poor nutrition and tissue perfusion, smoking, substance use, comorbidities (e.g. steroids) should be prescribed.

Department of Veterans Affairs 52

Department of Veterans Affairs Diabetes Community Pharmacies 52

pharmaphorum

JUNE 22, 2021

Blogger Chris Aldred and Joe Delahunty from Ascensia Diabetes Care have been working together to answer that question for five years. They are both keen to discuss what they’ve learned from years of witnessing patient-industry interactions and finding ways to make these efforts work better for people with diabetes.

Diabetes 52

Diabetes Communication 52

European Pharmaceutical Review

JULY 20, 2022

Our research looked at products that were voluntarily withdrawn, or had their licence revoked or suspended within the EU for a safety reason between 2012 and 2016. The types of adverse drug reactions examined included low blood pressure, diabetes, cancer, bleeding, involuntary movements and weight loss. Study focus. 2013;27(6):642-648.

Adverse Reactions 97

Adverse Reactions Diabetes Hospitals Vaccines 97

pharmaphorum

DECEMBER 23, 2020

Initially launched as a diabetes-focused joint venture with Sanofi in 2016, the French pharma company significantly scaled back its involvement in the firm last December, retaining just a small financial stake in it. Meanwhile, the last 12 months have seen a refocusing at Onduo.

Diabetes 59

Diabetes 59

RX Note

JUNE 11, 2023

Predisposing Factors Predisposing factors include Overzealous manicuring Nail biting Picking at a hangnail Thumb sucking Ingrown nail Diabetes mellitus Occupations in which the hands are frequently immersed in water Drugs such as antiretroviral agents, systemic retinoids, epidermal growth factor receptor inhibitors (e.g.

Diabetes 52

Diabetes Community Pharmacies 52

RX Note

JANUARY 21, 2023

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

Compounding 40

Compounding Community Pharmacies Clinical Pharmacology Dosage 40

Pharmaceutical Technology

MARCH 29, 2023

The collaboration between the companies began in 2016, for the purpose of identifying modifying treatments for a wide range of neurodegenerative diseases. Last May, Evotec and Sernova signed an exclusive worldwide strategic collaboration to develop a cell therapy for treating individuals with insulin-dependent diabetes.

Diabetes 52

Diabetes 52

European Pharmaceutical Review

FEBRUARY 22, 2023

Of the 175 new drugs approved by the US Food and Drug Administration (FDA) between 2016 and 2019, most were biologics. Lack of treatment persistence and treatment nonadherence as barriers to glycaemic control in patients with type 2 diabetes. Diabetes Therapy. The Business Research Company. Guerci B, Chanan N, Kaur S, et al.

Biosimilars 105

Biosimilars Diabetes Immunity Immunization 105

Pulses

AUGUST 3, 2023

Patient is a 19-year old female presenting to the ER with signs and symptoms of DKA (diabetic ketoacidosis) as evidenced by mental disorientation, random blood glucose of 452, persistent nausea and vomiting, and urinalysis positive for ketones. 2016 Aug 17 [cited 2020 Oct 9];31(5):437-447. A lab panel is pending. 2011 Mar;86(3):359-64.

Diabetes 52

Diabetes Labelling Hospitals 52

The Thyroid Pharmacist

NOVEMBER 4, 2022

Myo-inositol has been found to provide many valuable health effects, including anti-inflammatory, anti-oxidant, anti-diabetic, and anticancer effects. (7). They also concluded that patients testing with positive thyroid antibodies should be followed closely for diabetes mellitus and cardiovascular events. (1) doi:10.1155/2016/9537632.

Diabetes 98

Diabetes Dosage Compounding Immunity 98

PharmD Live

FEBRUARY 5, 2025

Studies of ancient Egyptian mummies show signs of atherosclerosis, indicating that heart disease was common even in ancient times ( Columbia Surgery, 2016 ). Diabetes and Insulin Resistance : High blood sugar levels damage blood vessels and nerves controlling the heart [ American Diabetes Association ]. What is Heart Disease?

Mayo Clinic 52

Mayo Clinic Medication Therapy Management (MTM) Diabetes 52

Pharmaceutical Technology

MARCH 1, 2023

The FDA approval of Sarepta’s Exondys 51 to treat Duchenne muscular dystrophy (DMD) and the approval of Ionis’ Spinraza to treat spinal muscular atrophy (SMA) in 2016 marked critical milestones in the field, as the first ASO drugs to enter the market. These include antisense oligonucleotides (ASO), RNA interference (RNAi), and RNA aptamers.

Vaccines 59

Vaccines Drug Development Diabetes 59

pharmaphorum

JULY 12, 2021

Bioelectronic medicine focuses on the fact that every organ in our bodies is innervated with neural networks, so electrical interfacing with peripheral nerves can be a potential pathway for diagnosing or treating diseases such as diabetes. The post Merck makes another bioelectronics play, partnering with Innervia appeared first on.

Labelling 52

Labelling Diabetes 52

pharmaphorum

FEBRUARY 7, 2022

In a statement, Bayer said that after reviewing the data for eliapixant (formerly BAY1817080 ) it had concluded that “the overall benefit no long outweighs the risk” in the drug’s four target indications – refractory chronic cough, endometriosis, overactive bladder and diabetic neuropathic pain.

Diabetes 52

Diabetes 52

pharmaphorum

JANUARY 28, 2021

More than 30 million Americans have diabetes and another 88 million are at risk of developing it. At the same time, the average cost of insulin for patients per year almost doubled from $2,864 to $5,705 between 2012 and 2016. Currently, more than seven million patients rely on insulin, and that number is growing each year.

Biosimilars 119

Biosimilars Insurance Coverage and Processing Drug Pricing Diabetes 119

pharmaphorum

JUNE 9, 2022

Diabetic foot ulcers could also, if proven effective, be treated with endolysins. As with atopic dermatitis, endolysin therapy can fill standard-of-care gaps to effectively protect those suffering with diabetic foot ulcers while protecting the patient from developing AMR. O’ Neil, 2016. Robles Aguilar, A. Gray, et al.

Drug Development 104

Drug Development Diabetes Chemotherapy 104

RX Note

FEBRUARY 4, 2024

Prevention in Public Health Pharmacists play a crucial role in primary healthcare, offering services like disease risk assessment, screening, patient referrals, disease management and medication optimization for noncommunicable diseases like cardiovascular conditions, asthma , chronic obstructive pulmonary disease and diabetes mellitus.

Community Pharmacies 52

Community Pharmacies Medical Records Compounding Diabetes 52

pharmaphorum

AUGUST 5, 2020

In a recent analysis of data from 2016 at the Queen Elizabeth Hospital Birmingham, 75% of unplanned admissions, which account for almost 30,000 admissions per year, were for older adults. The Association’s Dr Sheuli Porkess and Professor Janet Lord from the University of Birmingham tell us more.

Hospitals 80

Hospitals Labelling Diabetes Drug Development 80

Quality Matters

SEPTEMBER 9, 2024

The area is populated with apps and other software designed to treat various ailments including mental health disorders, diabetes, asthma, insomnia, substance-use disorders, and beyond. Patients can often use them from the comfort of their homes.

Labelling 52

Labelling Diabetes 52

RX Note

AUGUST 4, 2023

Apart from Malaysian Clinical Practice Guidelines , other recommended local references include: ADR Reporters Guide Ampang Protocol, 2012 Anticoagulation MTAC Protocol, 2020 Antidote Quick Guide, 2022 Cancer Drug Counselling A Guide for Pharmacist, 2017 Clinical Pharmacokinetics Pharmacy Handbook, 2019 Code of Ethics for Pharmacists, 2018 Critical (..)

Hospitals 52

Hospitals Inpatient Community Pharmacies Dosage 52

European Pharmaceutical Review

SEPTEMBER 5, 2024

This includes Glucox Biotech’s GLX7013114, which inhibits NOX4 and is in development for diabetic retinopathy. Advanz Pharma, which markets the drug in Europe, needed confirmatory data from further clinical studies to maintain its conditional marketing authorisation granted in 2016.

Immunity 59

Immunity Immunization Diabetes 59

pharmaphorum

DECEMBER 2, 2020

Others rapidly followed, including Glucotrol, aimed at diabetics, and Procardia, an anti-hypertensive. Since the turn of the millennium, Pfizer has embarked on a series of mega-mergers, gobbling up Warner-Lambert in 2000, Pharmacia and Upjohn in 2002, Wyeth in 2009, and Medivation in 2016.

Compounding 128

Compounding Vaccines Biosimilars Diabetes 128

European Pharmaceutical Review

JULY 27, 2023

Ibon was previously the Chief Science Officer at Richmond Research Institute (RRI) in London where he conducted clinical research in cardiac health, diabetes and several other conditions. Prior to joining RRI, he was Chief Scientific Officer at Histocell, a Spanish company developing cell-based therapies.

Diabetes 98

Diabetes 98

PharmaShots

MAY 23, 2023

Libmeldy received marketing authorization from the EMA on Dec 2020 for the treatment of Metachromatic Leukodystrophy (MLD), whereas, Strimvelis obtained the EMA’s approval in May 2016 for the treatment of Adenosine Deaminase Deficiency. develops and commercializes gene therapies targeting unmet therapeutic needs.

Diabetes 58

Diabetes Immunity Immunization Pharmaceutical Companies 58

RX Note

FEBRUARY 8, 2024

The drugs available at Malaysia is not available at US drug market and hence would not be covered in this book, such as benserazide/ levodopa combination (Madopar) in Parkinson disease and gliclazide in diabetes management.

Compounding 52

Compounding Hospitals Diabetes 52

PharmaShots

FEBRUARY 13, 2023

Discontinuations due to treatment-related AEs occurred in four treatment-naïve patients (11%) since the initiation of the PATHFINDER trial in 2018, and seven patients across lines of therapy (10%) since the initiation of the EXPLORER trial in 2016.

Chemotherapy 40

Chemotherapy Diabetes Immunity Immunization 40