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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

JAMA 2016; 316(20): 2115-25.) Healthcare providers review medication lists, adjust dosages, and coordinate care among multiple specialists. This responsibility impacts caregivers’ health and well-being, with approximately 20% reporting high physical strain and 40% experiencing emotional stress (Family Caregiver Alliance, 2016).

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Recommended Medical Reference

RX Note

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

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Episode 573: Ceiling dose of ketorolac for renal colic in the ED

Pharmacy Joe

In 1989, a study in the Journal of Clinical Pharmacology compared 10, 30, and 90 mg of IM ketorolac with placebo in 126 patients with cancer pain. In 2016, a trial by Sergey Motov confirmed this data by demonstrating IV ketorolac has an analgesic ceiling dose of 10 mg in ED patients with moderate to severe acute pain.