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In 1989, a study in the Journal of ClinicalPharmacology compared 10, 30, and 90 mg of IM ketorolac with placebo in 126 patients with cancer pain. In 2016, a trial by Sergey Motov confirmed this data by demonstrating IV ketorolac has an analgesic ceiling dose of 10 mg in ED patients with moderate to severe acute pain.
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