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Gender-affirming surgeries tripled in the U.S. between 2016-2019, study finds

STAT

nearly tripled between 2016 and 2019, according to new national estimates from a cohort study in JAMA Network Open. Over 48,000 people got some type of gender-affirming surgery between 2016-2020, with a slight decrease in the number of surgeries performed in 2020, likely because of the pandemic.

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STAT+: Two generic drugmakers pay $49 million to settle price-fixing charges

STAT

In 2016, a number of states filed what eventually became the first in a trio of lawsuits against many of the largest generic companies for allegedly coordinating efforts to fix and maintain prices for dozens of medications to treat a variety of ailments.

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Opinion: U.S. taxpayers should stop funding clinical trials of industry-owned drugs

STAT

  I worked closely with NCI’s Investigational Drug Branch (IDB) from 1990-2016, including as a principal investigator of one of only six contracts with NCI to conduct Phase 1 clinical trials from 1990-1995, and serving as co-chair of NCI’s Investigational Drug Steering Committee from 2005-2008.

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Opinion: Why isn’t there agreement on when women need to start getting mammograms?

STAT

The task force’s newest advice , which gives a “B” grade in favor of routine mammograms for women in their 40s, reverses its 2016 statement saying the test should be optional for such women. And that 2016 opinion conflicted with earlier task force recommendations.

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Opinion: What happened to obesity after Chile slew Tony the Tiger?

STAT

With some of the highest obesity levels in South America, the country had begun enforcing strict regulations on Frosted Flakes and other foods that exceeded set thresholds for sugar, calories, salt, or saturated fat in 2016. Read the rest…

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A doctor’s humbling journey treating long Covid: ‘The second we think we know what we are doing, we fall flat on our face’

STAT

I first met Wes Ely in 2016, when I wrote about ICU delirium and Ely’s attempts, as a critical-care physician at Vanderbilt University Medical Center, to urge fellow health care workers to rethink the use of heavy sedation in ICUs. Well, a lot’s happened since 2016.

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STAT+: Pharmalittle: We’re reading about copycat weight loss drugs, ADHD prescriptions spiking, and more

STAT

In 2016, Ionis won approval for an infusion called Spinraza.  Yet there were many older children and even some adults with debilitating but more mild disease who might be treated. Much  Much has changed, though, since Zolgensma’s earliest trials. After Zolgensma was approved, Roche won approval for a pill.