Digital Pharmacist

FEBRUARY 13, 2023

During this time he studied textbooks on the compounding of medicines and mastered his trade. Photo courtesy of APhA Mary Munson Runge (1928 – 2014) Mary Munson Runge was the daughter of a physician and pharmacy owner that was regarded as one of the most successful entrepreneurs in Donaldsonville, Louisiana.

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Community Pharmacies Hospitals Compounding 97

RX Note

JULY 8, 2023

Typically, new drugs are discovered through new insights into a disease process, unanticipated effects of existing treatment and tests of many novel molecular compounds. Lead optimization studies are carried out to identify compounds with the "best" properties (activity, toxicity, pharmacokinetic, physiochemical, etc.)

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Drug Development Compounding 52

pharmaphorum

MAY 7, 2021

For nearly 25 years, Jeremy has focused on aiding the biopharmaceutical and health sciences industry in the development of key compounds and new therapies. He has been reporting on the pharma industry since 2014 and has worked at a number of leading publications in the UK. About the interviewee. Jeremy Edwards is CEO of Xperiome.

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Drug Development Compounding 126

European Pharmaceutical Review

OCTOBER 23, 2023

In most cases, formulation compounds represent a fixed starting point from which any changes can be implemented, whereas tableting process parameters as well as machine condition, can be managed and optimised to their best, combining the knowledge of the machine manufacturer with the experience of the pharmaceutical industry.

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Compounding Pharmaceutical Manufacturing 98

RX Note

JANUARY 21, 2023

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

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Compounding Community Pharmacies Clinical Pharmacology Dosage 40

pharmaphorum

JUNE 7, 2022

The Hong Kong-based startup – one of an emerging crop of companies which are using artificial intelligence platforms to discover and design new therapeutic compounds – took its first drug into clinical trials in February.

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Compounding 52

pharmaphorum

JULY 9, 2014

The global pharmaceutical market passes a significant milestone in 2014: reaching one trillion US dollars in total value.

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Compounding 52

Eye on FDA

AUGUST 2, 2022

And since 2014 the Office of Prescription Drug Promotion (OPDP) has broken double digits only 3 times, producing only 6 letters in both 2020 an 2021. The characterization of investigative data resulted in a violation related to promotion of an unapproved compound. In 1998, there were 156 letters issued in a single year.

Communication 88

Communication Pharmaceutical Companies Pharmaceutical Companies Documentation 88

RX Note

JUNE 5, 2023

Workplace activity involves how healthcare workers use and handle the drug in the workplace - such as opening shipments, compounding, administering or cleaning up after use or spills. Oral hazardous drugs No crushing or compounding may be done in an unprotected environment. Consider having spill-response exercises or drills.

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Compounding Packaging Hospitals Chemotherapy 52

The Thyroid Pharmacist

AUGUST 18, 2023

Benefits and Uses of Curcumin Turmeric’s medicinal benefits can mostly be attributed to compounds called curcuminoids. Combining curcumin with piperine, an alkaloid found in black pepper, extends the life of curcumin in the body, making its compounds more therapeutically effective. 2014 Jul;69:182-201 [2] Prasad S, Aggarwal BB.

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Dosage Compounding Labelling Diabetes 98

pharmaphorum

JANUARY 9, 2023

It also has potential in NDD, although it was discontinued as a treatment of fragile X syndrome in 2014 after disappointing phase 2b trial results. The market potential of the CUD and NDD indications alone could top 2 billion euros ($2.12 billion) globally, the company noted. Lynn Durham.

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Compounding Drug Development 59

pharmaphorum

JANUARY 8, 2021

According to the figures compiled in the third quarter of last year, pharma brands were projected to spend around $10 billion in 2020 on digital advertising aimed at all groups including doctors, a compound annual growth rate of more than 13% since 2014.

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Communication Compounding 98

Pharmaceutical Technology

JANUARY 23, 2023

Out of the seven biologics approved to treat moderate to severe CD in adults, only the anti-TNFαs, Remicade (infliximab), and Humira (adalimumab), have been approved for paediatric patients, with Humira receiving the most recent approval in 2014.

Labelling 59

Labelling Compounding Drug Development 59

European Pharmaceutical Review

JANUARY 18, 2024

Insomnia market Dual orexin receptor antagonists (DORAs) [dual orexin receptor antagonists (DORAs)]… offer a new mechanism of action [in treating insomnia]” Across the seven major markets, the insomnia market is anticipated to grow at a compound annual growth rate (CAGR) of 2.6 percent from $3.2 billion in 2022 to $4.1

Drug Pricing 98

Drug Pricing Biosimilars Compounding 98

European Pharmaceutical Review

DECEMBER 21, 2022

Organic compounds are arguably the foundation of the pharmaceutical industry. All traditional small molecule pharmaceuticals include carbon building blocks” Organic compounds are arguably the foundation of the pharmaceutical industry. Chem Commun 2014, 50, 9650‒9652. Org Process Res Dev 2022, 26, 9, 2685–2693.

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Compounding Pharmaceutical Manufacturing Pharmaceutical Companies Pharmaceutical Companies 97

pharmaphorum

JANUARY 23, 2023

AbbVie paid Morphic $100 million upfront to claim a share of the programme in 2018, and stumped up another $20 million to opt into specific compounds in 2020, but pulled out altogether last year. The collaboration was focused on development of alpha V beta 6 drugs for fibrotic diseases, including idiopathic pulmonary fibrosis (IPF).

Compounding 52

Compounding 52

pharmaphorum

JANUARY 18, 2021

This has been compounded with the looming spectre of Brexit, which has meant the NHS lost some of its valuable workforce from overseas. Karina founded Acumentice in 2014, with a view to share this expertise through the development of clear and sustainable methodologies and frameworks.

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Compounding Hospitals 92

PharmD Live

MAY 13, 2024

It is estimated that approximately 90% of seniors aged 65 and older take at least one medication, 42% take five or more medications, and at least 18% are on ten or more drugs chronically. Data from the U.S. shows that the proportion of older adults taking five or more medications tripled from 13.8% in 1994 to 42.4%

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Long-Term Care Facilities Diabetes Nursing Homes Prescription Filling 105

The Happy PharmD

OCTOBER 28, 2024

billion in revenue by 2014, it paled in comparison to the colossal figures of CVS and Walgreens, which raked in $139 billion and $76 billion, respectively. Target’s overall profit margins were low, compounded by costly operational issues and the aftermath of shutting down its Canadian operations, which resulted in a $2.5

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Compounding Communication 52

Pharmacy Joe

OCTOBER 25, 2023

The removal appears to be in response to the publication of a 2021 article in the International Journal of Pharmaceutical Compounding. The list was originally compiled and updated by John Mitchell, PharmD, who passed away on June 10, 2014.

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Dosage Inpatient Packaging Documentation 52

pharmaphorum

JANUARY 27, 2023

An additional note of optimism is that UK biotechs achieved pivotal milestones in their development, with Verona Pharma reporting a successful phase 3 trial for Ensifentrine, the first novel compound in over 10 years to address the ongoing needs of more than 380 million patients worldwide suffering from Chronic Obstructive Pulmonary Disease (COPD).

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Compounding Pharmaceutical Companies Pharmaceutical Companies 52

The Pharmacist Blog

MARCH 28, 2015

compound interest with higher debt working against the pharmacist not accounted for). missed opportunity for compound interest). missed opportunity for free money and compound interest). Key take aways: save early, invest early, compound interest is your friend, minimize debt, live smart, and avoid being sucked into consumerism.

Pharmacy Technician 52

Pharmacy Technician Hospitals Compounding Inpatient 52

RX Note

JUNE 5, 2023

Phenylketonuria Risk Aspartame is catabolized to phenylalanine among other compounds, making it unsafe for consumption in individuals with phenylketonuria. Stability at High Temperature Aspartame is unstable at high temperatures and cannot be used for baking or cooking.

Packaging 52

Packaging Compounding Diabetes 52

RX Note

APRIL 7, 2024

Wart paints containing salicylic acid or similar compounds Acts by softening and destroying the lesion by chemically burning, thus mechanically removing affected tissue. Topical salicylic acid and liquid nitrogen cryotherapy have the best evidence for efficacy. The former is less painful. Surgical removal (e.g.

Compounding 52

Compounding Immunity Immunization Community Pharmacies 52

pharmaphorum

FEBRUARY 18, 2021

Eli Lilly’s Humalog compound and formulation patents expired in 2013 and 2014, respectively. The history of insulin captures one of the mystifying complexities of the pharmaceutical market — how long-standing drugs become more expensive with time and competition fails to hold down prices.

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Prescription Filling Drug Pricing Biosimilars Compounding 52

Quality Matters

MARCH 1, 2024

USP has a long-standing history of healthcare standards including those for compounding preparations that are tailored to meet the unique needs of patients who may not otherwise have access to their medications. Washington (DC): 2014; pharmacogenomics working group whose mission is to develop a 56. Nature 520, 609–611 (2015).

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Labelling Compounding 52

The Thyroid Pharmacist

FEBRUARY 17, 2023

A study in 2014 investigated NAC’s effectiveness in preventing the formation of biofilms, as well as in the destruction of existing ones. NAC’s sulfurous compounds can often cause a “rotten-egg” smell — but that is normal! 2014 Oct;18(19):2942-8. [20] Amino Acids. 2017;49(12):1915-1929. A systematic review. 2017;19(1):11-17.

Diabetes 98

Diabetes Immunity Immunization Dosage 98

The Thyroid Pharmacist

NOVEMBER 4, 2022

While the human body (via the liver and kidneys) can produce up to 4 g/day of inositol, it has been found that the overly processed, high glucose (and low fiber) Western diets that many people follow, only provide about 1 g/day of the compound. (7). 2014 Jan;29(1):55-63. Recommended Dosage and Precautions. Int J Endocrinol.

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Diabetes Dosage Compounding Immunity 98

The Thyroid Pharmacist

OCTOBER 21, 2022

In general, the anti-bacterial compounds derived from plant sources tend to spare the healthy gut bacteria more so than pharmacological antibiotics, which may decrease the risk of diarrhea and other digestive complications. 2014 May; 3(3): 16–24. Chedid V, Dhalla S, Clarke JO, Chander Roland B, Dunbar KB, Koh J, et al. Ventola CL.

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Dosage Compounding 131

The Thyroid Pharmacist

APRIL 21, 2023

Multitasking adaptogens Adaptogens are plant compounds that are known for helping to increase the body’s resilience to stress, and can help balance the HPA axis. doi:10.1155/2014/904834 Mahoney DE, Hiebert JB, Thimmesch A, et al. We can find magnesium in dark leafy greens, nuts, seeds, avocado, and dark chocolate. Phys Act Nutr.

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Compounding 86

The Thyroid Pharmacist

AUGUST 19, 2022

25) A 2014 study looked at the co-occurring rates of autoimmune gastritis in people with Hashimoto’s, as autoimmune gastritis may contribute to the malabsorption of thyroid medication and require a person to need a higher dose of thyroid hormone. (26). July 5, 2014. pylori bacteria and eradicate it. (39) J Physiol Pharmacol.

Health and Personal Care Stores 98

Health and Personal Care Stores Immunity Immunization Dosage 98

The Thyroid Pharmacist

SEPTEMBER 20, 2024

63] Many of the benefits of ginger are due to gingerol and shogaol, compounds called gingeroids, which may also help with bloating, belching, and discomfort after meals. [64] Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; November 17, 2014. [29] Published 2014 Feb 28. J Pediatr Gastroenterol Nutr.

Health and Personal Care Stores 75

Health and Personal Care Stores Diabetes Chemotherapy Medication Therapy Management (MTM) 75

The Thyroid Pharmacist

SEPTEMBER 2, 2022

A follow-up study in 2014 showed that the myo-inositol isoform specifically improves the metabolic profile of individuals with PCOS. Milk Thistle: Silymarin (one of the compounds in milk thistle) may be therapeutic in metabolic syndrome (insulin resistance syndrome) in its potential to improve insulin sensitivity and decrease blood sugar.

Diabetes 98

Diabetes Health and Personal Care Stores Immunity Immunization 98

European Pharmaceutical Review

JULY 13, 2023

While this is essential in the interrogation of novel compounds for which we know very little about their efficacy and safety, it is also true that some biomedical research is highly wasteful. 3 Moreover, some studies have suggested that co-administration of these compounds can modulate the effects of one another at a receptor level.

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Compounding Drug Development Clinical Pharmacology Documentation 98

The Thyroid Pharmacist

NOVEMBER 3, 2023

9] When the body is exposed to an allergen, histamine production increases and turns on inflammatory processes to protect the body from that compound. In 2014, Americans filled more than 170 million prescriptions for PPIs, and they are generally over-prescribed. [19]

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Immunity Immunization Dosage Mayo Clinic 98

PharmaShots

FEBRUARY 22, 2023

In the US, Trulicity is protected by a compound patent (2027) and by biologics data protection (2026). million patients’ journeys with type 2 diabetes since 2014. Active Ingredient: dulaglutide Dosage Forms & Strengths: Injection: 0.75 mL, 3 mg/0.5 Trulicity has been a part of over 2.8

Diabetes 64

Diabetes Compounding Dosage Communication 64

pharmaphorum

DECEMBER 2, 2020

It was at this time they set their site at Sandwich in the UK, initially just to finish processing compounds imported from America, but due to tariffs on imported products the company rapidly expanded the plant to accommodate producing medicines from scratch. Likewise, tanezumab, an anti-osteoarthritic, failed in trials.

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Compounding Vaccines Biosimilars Diabetes 128