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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

Medication Non-Adherence Polypharmacy increases the likelihood of medication non-adherence due to the complexity and confusion of managing multiple medications.Patients often struggle with the regimen, missing doses, taking incorrect dosages, or discontinuing medications altogether, which can lead to suboptimal treatment results.

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Micromedex

RX Note

In my experience, there are increasingly more off-label uses and dosages included in this resource. NeoFax is one of the most widely used neonatal drug dosing but has been discontinued in print format since June 2012 (The last copy was the 2011 edition ).

Dosage 52
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Galactagogues

RX Note

Dosage in most published studies Domperidone 10 mg 3 times daily for 4 to 10 days. Metoclopramide 10 mg 2 or 3 times daily for 7 to 14 days. Summary While there is not a strict list of foods to avoid while breastfeeding, it is generally recommended to maintain a balanced diet and limit certain foods or beverages.

Dosage 52
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The Fourth Circuit Upholds CMS’ Definition of “Line-Extension Drug” and “New Formulation”

FDA Law Blog: Biosimilars

To address concerns that manufacturers were making minor changes to drugs in order for them to be characterized as new covered outpatient drugs with updated (and higher) baseline AMPs, Congress amended the statute in 2010 to add an alternative rebate for line extensions of oral dosage form single source or innovator multiple source drugs (i.e.,

Dosage 59
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CMS Definition of “New Formulation” Upheld in Federal Court

FDA Law Blog: Biosimilars

In 2010, concerned that manufacturers were making minor changes to a drug merely so that it could be characterized as new covered outpatient drug with an updated baseline AMP, Congress added to the statute an alternative rebate for line extensions of oral dosage form innovator (i.e., NDA or BLA) drugs.

Dosage 59
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Prescribing Red Flags and Suspicious Controlled Substance Orders: Current Cautionary Tales

FDA Law Blog: Biosimilars

12, 2012). “[W]hen the circumstances surrounding the presentation of a prescription would give rise to suspicion in a ‘reasonable professional,’ there is a duty to question the prescription.” The Zarzamora decision identifies the following as prescribing red flags at issue in the case: 1. Holiday CVS, L.L.C. d/b/a CVS/Pharmacy, Nos.

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Computed tomography for in-depth investigation of freeze-dried products

European Pharmaceutical Review

X-ray technology is also increasingly used in pharmaceutical R&D, particularly for examining solid dosage forms, an application for which this technology can be seamlessly adopted. X-ray Microtomography of Solid Dosage Forms. Biomed Opt Express 2012; 3(1): 55–63 [[link] 22254168] 8. Wiesbaden: Vieweg+Teubner Verlag 2012.

Dosage 98