pharmaphorum

JANUARY 19, 2022

EQRx’s GEMSTONE-302 study evaluated the efficacy and safety of the investigational anti-PD-L1 antibody, sugemalimab, in combination with chemotherapy as a first-line treatment for patients with stage four non-small cell lung cancer (NSCLC), versus using chemotherapy alone. But prevalence still increased by 10% between 2008 and 2012.

Chemotherapy 59

Chemotherapy Immunity Immunization 59

Pharmaceutical Technology

APRIL 24, 2023

For example, a widely referenced study from 2012 reported that up to 50% of approved drugs between 1981 and 2010 were directly or indirectly from natural products, while according to the WHO, 11% of drugs considered basic or essential originated from flowering plants.

Compounding 105

Compounding Chemotherapy 105

European Pharmaceutical Review

MAY 4, 2023

Amivantamab was the first bispecific monoclonal antibody (BsMAb) approved in the EU to treat advanced NSCLC with EGFR exon 20 insertion mutations post chemotherapy. 2012; 23(8): 6 – 9. These patients face a poorer prognosis and shorter survival rates compared with lung cancer driven by more common EGFR mutations. Cancer Ther.

Immunization 98

Immunization Immunity Chemotherapy 98

RX Note

JULY 29, 2023

To illustrate, in the management of nausea and vomiting induced by cytotoxic chemotherapy or radiotherapy, the dose of IV granisetron is 10 mcg/kg in Lexicomp , but 10-40 mcg/kg (max per dose 3mg) in British National Formulary.

Chemotherapy 40

Chemotherapy Labelling 40

pharmaphorum

APRIL 20, 2021

Zytiga is the older of the two drugs and was used in the active control arm of the ACIS study, which tested the combination of Erleada (apalutamide) and Zytiga (abiraterone) in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC).

Chemotherapy 52

Chemotherapy 52

pharmaphorum

SEPTEMBER 29, 2020

China’s Junshi Biosciences has said it plans filings for a new cancer immunotherapy after its toripalimab outperformed standard chemotherapy in cancer of the upper throat in a phase 3 trial. Toripalimab is a PD-1 inhibitor that is already approved for treatment of metastatic melanoma in China.

Chemotherapy 40

Chemotherapy Biosimilars 40

European Pharmaceutical Review

JULY 4, 2023

Since the first ADC was approved by the EMA in 2012, they have generated a great deal of interest in the oncology field because of their potential to address many of the challenges of traditional chemotherapy options.

Drug Development 98

Drug Development Communication Dosage Chemotherapy 98

pharmaphorum

OCTOBER 19, 2022

It was the summer of 2012 and I had just turned 37, my son was about to celebrate his first birthday and my daughter had just started school. She told me I had advanced breast cancer and urged me to drive down to the local emergency room immediately to get additional tests and start chemotherapy that weekend.

Chemotherapy 52

Chemotherapy 52

RX Note

JULY 29, 2023

External Links Understanding Unapproved Use of Approved Drugs "Off Label" Medicines for Children - Unlicensed Medicines NICE Evidence Summaries Ten Common Questions (and Their Answers) About Off-label Drug Use, 2012 Off-label medicine use: Ethics, practice and future directions, 2021

Labelling 40

Labelling Dosage Immunity Immunization 40

ID Stewardship

DECEMBER 26, 2022

As someone who enjoys the simplicity of Sesame Street and the complexity of Antimicrobial Chemotherapy, this one was near and dear to my heart as well as a long time coming. July 2012 – @IDstewardship joined Twitter. EDITOR’S CHOICE: BEST ARTICLE OF 2022. This was the most fun article to work on this year. CONTRIBUTORS SHOUT-OUT.

Chemotherapy 52

Chemotherapy Hospitals 52

pharmaphorum

APRIL 20, 2022

In 2012, Jennifer Doudna and Emmanuelle Charpentier published a paper in Science where they outlined isolating the components of the CRISPR-Cas9 system and demonstrated how it could be used to cut specific sites in isolated DNA. This would go some way to removing the damage that chemotherapy can do to healthy cells. The pipeline.

Chemotherapy 52

Chemotherapy Immunization Immunity Drug Development 52

pharmaphorum

MARCH 9, 2021

Now, people living with particular types of lymphoma have individualised options beyond chemotherapy for the first time.”. 2012, page 4. “Although there are standards of care for first- and second-line treatments – until the arrival of cell therapy, there were limited further treatment options for some patients facing end of life.

Chemotherapy 52

Chemotherapy Communication Immunization Immunity 52

PharmaShots

MARCH 29, 2023

It is the only drug in its class of chemotherapy and is developed from the natural substance found in a sea sponge. Halaven binds to the tumor, blocks cell division, and causes cell death. During 1st cycle of treatment, Halaven is injected as an infusion over a short period of 2-5 mins once a week for two weeks and skipped for one week.

Biosimilars 49

Biosimilars Diabetes Chemotherapy Immunization 49

RX Note

AUGUST 4, 2023

You may also refresh knowledge of clinical pharmacokinetics , total parenteral nutrition or chemotherapy before entering the relevant rotations. You should be at least familiar with insulin and inhalers counselling before entering ward, inpatient or outpatient. What to do if I did not know the answer to questions from patients or doctors?

Hospitals 52

Hospitals Inpatient Community Pharmacies Dosage 52

Pharmaceutical Technology

JULY 23, 2008

With expensive new treatments, increasing numbers of patients in chemotherapy in major markets and developing nations like China, Brazil and Russia investing more in treating and diagnosing cancer, IMS predicts a compound growth rate of 12–15% and tips the global market to reach $80bn by 2012.

Pharmaceutical Companies 40

Pharmaceutical Companies Pharmaceutical Companies Compounding Biosimilars 40

The Thyroid Pharmacist

SEPTEMBER 20, 2024

Chemotherapy agents: Chemotherapy agents can lead to constipation in a variety of ways such as slowing the movements of the intestinal tract or creating inflammation that disrupts digestive function. Chemotherapy-Induced Constipation and Diarrhea: Pathophysiology, Current and Emerging Treatments. link] Published March 13, 2012.

Health and Personal Care Stores 75

Health and Personal Care Stores Diabetes Chemotherapy Medication Therapy Management (MTM) 75

The Thyroid Pharmacist

AUGUST 26, 2022

10-13) For example, research relating to cancer and the use of chemotherapy drugs found that carnitine supplementation was able to help reverse muscle damage and weakness caused by toxic side effects of anticancer drugs. (38). Published October 8, 2012. Role of carnitine in cancer chemotherapy-induced multiple organ toxicity.

Diabetes 98

Diabetes Immunity Immunization Chemotherapy 98